Department of Pediatric Rheumatology and Immunology
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Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2008 | Pubmed ID: 18802069
Early detection of severe cholestatic hepatopathy in COACH syndrome.
American journal of medical genetics Sep, 2002 | Pubmed ID: 12210305
S100A12 (EN-RAGE) in monitoring Kawasaki disease.
Lancet Apr, 2003 | Pubmed ID: 12699958
Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis.
Arthritis and rheumatism Sep, 2003 | Pubmed ID: 13130482
Absence of S100A12 in mouse: implications for RAGE-S100A12 interaction.
Trends in immunology Dec, 2003 | Pubmed ID: 14644132
Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?
Annals of the rheumatic diseases Feb, 2004 | Pubmed ID: 14722212
Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations.
Arthritis and rheumatism Apr, 2004 | Pubmed ID: 15077313
Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation.
Clinica chimica acta; international journal of clinical chemistry Jun, 2004 | Pubmed ID: 15149869
Wegener granulomatosis in childhood and adolescence.
European journal of pediatrics Aug, 2004 | Pubmed ID: 15168108
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.
Blood Dec, 2004 | Pubmed ID: 15331440
Neutrophil-derived S100A12 is profoundly upregulated in the early stage of acute Kawasaki disease.
The American journal of cardiology Sep, 2004 | Pubmed ID: 15374807
Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis.
The Journal of pathology Nov, 2004 | Pubmed ID: 15476267
Proinflammatory S100 proteins in arthritis and autoimmune disease.
Arthritis and rheumatism Dec, 2004 | Pubmed ID: 15593206
Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.
Blood Apr, 2005 | Pubmed ID: 15598812
Differential expression and response to anti-TNFalpha treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis.
The Journal of pathology May, 2005 | Pubmed ID: 15809977
Early activation of cutaneous vessels and epithelial cells is characteristic of acute systemic onset juvenile idiopathic arthritis.
Experimental dermatology Apr, 2005 | Pubmed ID: 15810883
Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis.
Arthritis research & therapy , 2005 | Pubmed ID: 15899044
S100 proteins in monitoring inflammation: the importance of a gold standard and a validated methodology.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2005 | Pubmed ID: 16148085
Systemic juvenile rheumatoid arthritis: cognitive function and social adjustment.
Annals of neurology Oct, 2005 | Pubmed ID: 16178013
Carboxylated glycans mediate colitis through activation of NF-kappa B.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2005 | Pubmed ID: 16210648
S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules.
Journal of leukocyte biology Jan, 2007 | Pubmed ID: 16943388
Expression of myeloid-related protein-8 and -14 in patients with acute Kawasaki disease.
Journal of the American College of Cardiology Sep, 2006 | Pubmed ID: 16979015
Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis.
Annals of the rheumatic diseases Aug, 2007 | Pubmed ID: 17223658
Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome.
Critical care medicine May, 2007 | Pubmed ID: 17414728
Mechanisms of disease: a 'DAMP' view of inflammatory arthritis.
Nature clinical practice. Rheumatology Jul, 2007 | Pubmed ID: 17599072
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
Nature medicine Sep, 2007 | Pubmed ID: 17767165
Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12.
Arthritis and rheumatism Dec, 2007 | Pubmed ID: 18050248
RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis.
Carcinogenesis Oct, 2008 | Pubmed ID: 18689872
Phagocyte-specific S100 proteins are released from affected mucosa and promote immune responses during inflammatory bowel disease.
The Journal of pathology Oct, 2008 | Pubmed ID: 18729068
S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin.
Arthritis and rheumatism Dec, 2008 | Pubmed ID: 19035478
Monitoring disease activity by stool analyses: from occult blood to molecular markers of intestinal inflammation and damage.
Gut Jun, 2009 | Pubmed ID: 19136508
Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome.
The American journal of gastroenterology Feb, 2009 | Pubmed ID: 19174795
The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis.
Arthritis and rheumatism Mar, 2009 | Pubmed ID: 19248102
Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function.
BMC biochemistry , 2009 | Pubmed ID: 19386136
Infliximab reduces the cytokine-mediated inflammation but does not suppress cellular infiltration of the vessel wall in refractory Kawasaki disease.
Pediatric research Jun, 2009 | Pubmed ID: 19430379
The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer.
Journal of leukocyte biology Sep, 2009 | Pubmed ID: 19451397
Diagnostic value of [(18)F]-FDG PET/CT in children with fever of unknown origin or unexplained signs of inflammation.
European journal of nuclear medicine and molecular imaging Jan, 2010 | Pubmed ID: 19526234
Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever.
Annals of the rheumatic diseases Apr, 2010 | Pubmed ID: 19762364
Expression and role of myeloid-related protein-14 in clinical and experimental sepsis.
American journal of respiratory and critical care medicine Dec, 2009 | Pubmed ID: 19762566
Achalasia mistaken as eating disorders: report of two children and review of the literature.
European journal of gastroenterology & hepatology Jul, 2010 | Pubmed ID: 19809334
Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial.
JAMA : the journal of the American Medical Association Apr, 2010 | Pubmed ID: 20371785
Keratinocytes determine Th1 immunity during early experimental leishmaniasis.
PLoS pathogens Apr, 2010 | Pubmed ID: 20442861
The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells.
Nature medicine Jun, 2010 | Pubmed ID: 20473308
Carboxylated N-glycans on RAGE promote S100A12 binding and signaling.
Journal of cellular biochemistry Jun, 2010 | Pubmed ID: 20512925
Body mass index and creatinine clearance are associated with steady-state serum concentrations of the cell damage marker S100B in renal transplant recipients.
Medical science monitor : international medical journal of experimental and clinical research Jul, 2010 | Pubmed ID: 20581773
Life-threatening hypersplenism due to idiopathic portal hypertension in early childhood: case report and review of the literature.
BMC gastroenterology , 2010 | Pubmed ID: 20961440
Noninvasive assessment of pediatric inflammatory bowel disease with ¹⁸F-fluorodeoxyglucose-positron emission tomography and computed tomography.
European journal of gastroenterology & hepatology Jan, 2011 | Pubmed ID: 21042220
B cell depletion for autoimmune diseases in paediatric patients.
Clinical rheumatology Jan, 2011 | Pubmed ID: 21120559
Translational research network and patient registry for auto-inflammatory diseases.
Rheumatology (Oxford, England) Jan, 2011 | Pubmed ID: 21148158
The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.
American journal of physiology. Gastrointestinal and liver physiology May, 2011 | Pubmed ID: 21311028
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome.
Arthritis and rheumatism Mar, 2011 | Pubmed ID: 21360513
Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease.
Journal of pediatric gastroenterology and nutrition May, 2011 | Pubmed ID: 21502824
Therapeutic approaches in the treatment of juvenile dermatomyositis in patients with recent-onset disease and in those experiencing disease flare: an international multicenter PRINTO study.
Arthritis and rheumatism Oct, 2011 | Pubmed ID: 21647864
MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes.
Annals of the rheumatic diseases Dec, 2011 | Pubmed ID: 21908452
The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.
Annals of the rheumatic diseases Jun, 2012 | Pubmed ID: 22267331
CREMα overexpression decreases IL-2 production, induces a T(H)17 phenotype and accelerates autoimmunity.
Journal of molecular cell biology Apr, 2012 | Pubmed ID: 22355096
Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation.
Arthritis and rheumatism Sep, 2012 | Pubmed ID: 22549726
Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study.
Annals of the rheumatic diseases Dec, 2012 | Pubmed ID: 22689317
Fecal phagocyte-specific S100A12 for diagnosing necrotizing enterocolitis.
The Journal of pediatrics Dec, 2012 | Pubmed ID: 22796048
Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome.
Journal of leukocyte biology Nov, 2012 | Pubmed ID: 22892107
The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis.
The EMBO journal Jan, 2013 | Pubmed ID: 23188082
Phagocyte-derived S100 proteins in autoinflammation: putative role in pathogenesis and usefulness as biomarkers.
Clinical immunology (Orlando, Fla.) Jun, 2013 | Pubmed ID: 23269200
Improving relapse prediction in inflammatory bowel disease by neutrophil-derived S100A12.
Inflammatory bowel diseases May, 2013 | Pubmed ID: 23377171
Fecal S100A12: identifying intestinal distress in very-low-birth-weight infants.
Journal of pediatric gastroenterology and nutrition Aug, 2013 | Pubmed ID: 23549327
Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4.
American journal of respiratory and critical care medicine Jun, 2013 | Pubmed ID: 23611140
Peripheral monocyte functions and activation in patients with quiescent Crohn's disease.
PloS one , 2013 | Pubmed ID: 23658649
Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens.
Arthritis research & therapy May, 2013 | Pubmed ID: 23718630
Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis.
Arthritis and rheumatism Sep, 2013 | Pubmed ID: 23754188
Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome.
Arthritis and rheumatism Nov, 2013 | Pubmed ID: 23983059
Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease.
The American journal of gastroenterology Dec, 2013 | Pubmed ID: 24145675
MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.
Annals of the rheumatic diseases Dec, 2013 | Pubmed ID: 24297376
Validation of relapse risk biomarkers for routine use in patients with juvenile idiopathic arthritis.
Arthritis care & research Jun, 2014 | Pubmed ID: 24339418
Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout.
Arthritis & rheumatology (Hoboken, N.J.) May, 2014 | Pubmed ID: 24470119
Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome.
World journal of gastroenterology : WJG Jan, 2014 | Pubmed ID: 24574706
Significance of hydrogen breath tests in children with suspected carbohydrate malabsorption.
BMC pediatrics , 2014 | Pubmed ID: 24575947
A12: The Role of Serum S100A12 Protein Levels in Disease Flare After Withdrawal of Anti-tumor Necrosis Factor Therapy in Polyarticular Forms of Juvenile Idiopathic Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) Mar, 2014 | Pubmed ID: 24677901
A20: Understanding the Use and Biology of TNF Therapy in JIA-Clinical Outcomes.
Arthritis & rheumatology (Hoboken, N.J.) Mar, 2014 | Pubmed ID: 24677947
A68: The Role of Serum S100A12 Protein Levels in Maintaining Inactive Disease on Anti-tumor Necrosis Factor Therapy in Polyarticular Forms of Juvenile Idiopathic Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) Mar, 2014 | Pubmed ID: 24677999
Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis).
Pediatric rheumatology online journal , 2014 | Pubmed ID: 24891844
Activated STING in a vascular and pulmonary syndrome.
The New England journal of medicine Aug, 2014 | Pubmed ID: 25029335
Monocyte-induced development of Th17 cells and the release of S100 proteins are involved in the pathogenesis of graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2014 | Pubmed ID: 25187661
Management of juvenile idiopathic arthritis: hitting the target.
Nature reviews. Rheumatology May, 2015 | Pubmed ID: 25561365
Reprogramming of monocytes by GM-CSF contributes to regulatory immune functions during intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2015 | Pubmed ID: 25653427
Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.
The Journal of allergy and clinical immunology Nov, 2015 | Pubmed ID: 26025129
Redox distress and genetic defects conspire in systemic autoinflammatory diseases.
Nature reviews. Rheumatology Nov, 2015 | Pubmed ID: 26241183
MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis.
Arthritis research & therapy Aug, 2015 | Pubmed ID: 26249667
Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy.
Inflammatory bowel diseases Jan, 2016 | Pubmed ID: 26457379
Increased serum concentrations of neutrophil-derived protein S100A12 in heterozygous carriers of MEFV mutations.
Clinical and experimental rheumatology Nov-Dec, 2015 | Pubmed ID: 26486615
Sleep Fragmentation and Biomarkers in Juvenile Idiopathic Arthritis.
Biological research for nursing May, 2016 | Pubmed ID: 26512051
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2015 | Pubmed ID: 26598658
No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis.
Pediatric rheumatology online journal Dec, 2015 | Pubmed ID: 26667304
[Translational research in pediatric rheumatology. Current research approaches to the innate immune system].
Zeitschrift fur Rheumatologie Apr, 2016 | Pubmed ID: 26800663
Correlation of Secretory Activity of Neutrophils With Genotype in Patients With Familial Mediterranean Fever.
Arthritis & rheumatology (Hoboken, N.J.) 12, 2016 | Pubmed ID: 27333294
Review of biomarkers in systemic juvenile idiopathic arthritis: helpful tools or just playing tricks?
Arthritis research & therapy 07, 2016 | Pubmed ID: 27411444
Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets.
Joint, bone, spine : revue du rhumatisme Jul, 2017 | Pubmed ID: 27659403
Partial correction of neutrophil dysfunction by oral galactose therapy in glycogen storage disease type Ib.
International immunopharmacology Mar, 2017 | Pubmed ID: 28126686
Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39+/CD73+ Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells.
Cellular and molecular gastroenterology and hepatology Jul, 2015 | Pubmed ID: 28210690
Proinflammatory Cytokine Environments Can Drive Interleukin-17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) 07, 2017 | Pubmed ID: 28296284
Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
Arthritis & rheumatology (Hoboken, N.J.) 07, 2017 | Pubmed ID: 28371513
Munchausen by proxy syndrome mimicking systemic autoinflammatory disease: case report and review of the literature.
Pediatric rheumatology online journal Apr, 2017 | Pubmed ID: 28381287
Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.
Blood 03, 2018 | Pubmed ID: 29326099
S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.
The Journal of rheumatology 04, 2018 | Pubmed ID: 29335345
Identification of an Amino Acid Motif in HLA-DRβ1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis.
Arthritis & rheumatology (Hoboken, N.J.) 07, 2018 | Pubmed ID: 29513936
IL-6 blockade in systemic juvenile idiopathic arthritis - achievement of inactive disease and remission (data from the German AID-registry).
Pediatric rheumatology online journal Apr, 2018 | Pubmed ID: 29622022
The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).
Rheumatology international Apr, 2018 | Pubmed ID: 29637325
Treating juvenile idiopathic arthritis to target: recommendations of an international task force.
Annals of the rheumatic diseases 06, 2018 | Pubmed ID: 29643108
JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.
The Journal of clinical investigation 07, 2018 | Pubmed ID: 29649002
Proteomics in Chronic Arthritis-Will We Finally Have Useful Biomarkers?
Current rheumatology reports 07, 2018 | Pubmed ID: 30008153
Calcium and zinc tune autoinflammatory Toll-like receptor 4 signaling by S100A12.
The Journal of allergy and clinical immunology 10, 2018 | Pubmed ID: 30010542
The role of S100 proteins in the pathogenesis and monitoring of autoinflammatory diseases.
Molecular and cellular pediatrics Sep, 2018 | Pubmed ID: 30255357
Monocyte-Derived Interleukin-1β As the Driver of S100A12-Induced Sterile Inflammatory Activation of Human Coronary Artery Endothelial Cells: Implications for the Pathogenesis of Kawasaki Disease.
Arthritis & rheumatology (Hoboken, N.J.) May, 2019 | Pubmed ID: 30447136
Evaluation of the S100 protein A12 as a biomarker of neonatal sepsis.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Dec, 2018 | Pubmed ID: 30563403
Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study.
The Lancet. Child & adolescent health Apr, 2019 | Pubmed ID: 30819662
Molecular signature characterisation of different inflammatory phenotypes of systemic juvenile idiopathic arthritis.
Annals of the rheumatic diseases Aug, 2019 | Pubmed ID: 31005900
Classification criteria for autoinflammatory recurrent fevers.
Annals of the rheumatic diseases Aug, 2019 | Pubmed ID: 31018962
The German National Registry of Primary Immunodeficiencies (2012-2017).
Frontiers in immunology , 2019 | Pubmed ID: 31379802
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