Dirk Foell

Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells.

Early detection of severe cholestatic hepatopathy in COACH syndrome.

S100A12 (EN-RAGE) in monitoring Kawasaki disease.

Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis.

Absence of S100A12 in mouse: implications for RAGE-S100A12 interaction.

Methotrexate treatment in juvenile idiopathic arthritis: when is the right time to stop?

Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations.

Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation.

Wegener granulomatosis in childhood and adolescence.

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes.

Neutrophil-derived S100A12 is profoundly upregulated in the early stage of acute Kawasaki disease.

Early recruitment of phagocytes contributes to the vascular inflammation of giant cell arteritis.

Proinflammatory S100 proteins in arthritis and autoimmune disease.

Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells.

Differential expression and response to anti-TNFalpha treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis.

Early activation of cutaneous vessels and epithelial cells is characteristic of acute systemic onset juvenile idiopathic arthritis.

Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis.

S100 proteins in monitoring inflammation: the importance of a gold standard and a validated methodology.

Systemic juvenile rheumatoid arthritis: cognitive function and social adjustment.

Carboxylated glycans mediate colitis through activation of NF-kappa B.

S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules.

Expression of myeloid-related protein-8 and -14 in patients with acute Kawasaki disease.

Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis.

Neutrophil-derived S100A12 in acute lung injury and respiratory distress syndrome.

Mechanisms of disease: a 'DAMP' view of inflammatory arthritis.

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.

Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12.

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis.

Phagocyte-specific S100 proteins are released from affected mucosa and promote immune responses during inflammatory bowel disease.

S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin.

Monitoring disease activity by stool analyses: from occult blood to molecular markers of intestinal inflammation and damage.

Elevated human beta-defensin-2 levels indicate an activation of the innate immune system in patients with irritable bowel syndrome.

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis.

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function.

Infliximab reduces the cytokine-mediated inflammation but does not suppress cellular infiltration of the vessel wall in refractory Kawasaki disease.

The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer.

Diagnostic value of [(18)F]-FDG PET/CT in children with fever of unknown origin or unexplained signs of inflammation.

Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever.

Expression and role of myeloid-related protein-14 in clinical and experimental sepsis.

Achalasia mistaken as eating disorders: report of two children and review of the literature.

Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial.

Keratinocytes determine Th1 immunity during early experimental leishmaniasis.

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells.

Carboxylated N-glycans on RAGE promote S100A12 binding and signaling.

Body mass index and creatinine clearance are associated with steady-state serum concentrations of the cell damage marker S100B in renal transplant recipients.

Life-threatening hypersplenism due to idiopathic portal hypertension in early childhood: case report and review of the literature.

Noninvasive assessment of pediatric inflammatory bowel disease with ¹⁸F-fluorodeoxyglucose-positron emission tomography and computed tomography.

B cell depletion for autoimmune diseases in paediatric patients.

Translational research network and patient registry for auto-inflammatory diseases.

The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.

Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome.

Granulocyte macrophage-colony-stimulating factor autoantibodies and increased intestinal permeability in Crohn disease.

Therapeutic approaches in the treatment of juvenile dermatomyositis in patients with recent-onset disease and in those experiencing disease flare: an international multicenter PRINTO study.

MRP8 and MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes.

The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis.

CREMα overexpression decreases IL-2 production, induces a T(H)17 phenotype and accelerates autoimmunity.

Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation.

Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study.

Fecal phagocyte-specific S100A12 for diagnosing necrotizing enterocolitis.

Staphylococcus aureus Panton-Valentine leukocidin induces an inflammatory response in human phagocytes via the NLRP3 inflammasome.

The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis.

Phagocyte-derived S100 proteins in autoinflammation: putative role in pathogenesis and usefulness as biomarkers.

Improving relapse prediction in inflammatory bowel disease by neutrophil-derived S100A12.

Fecal S100A12: identifying intestinal distress in very-low-birth-weight infants.

Proinflammatory S100A12 can activate human monocytes via Toll-like receptor 4.

Peripheral monocyte functions and activation in patients with quiescent Crohn's disease.

Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens.

Long-term safety and efficacy of rilonacept in patients with systemic juvenile idiopathic arthritis.

Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome.

Granulocyte macrophage colony-stimulating factor auto-antibodies and disease relapse in inflammatory bowel disease.

MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis.

Validation of relapse risk biomarkers for routine use in patients with juvenile idiopathic arthritis.

Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout.

Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome.

Significance of hydrogen breath tests in children with suspected carbohydrate malabsorption.

A12: The Role of Serum S100A12 Protein Levels in Disease Flare After Withdrawal of Anti-tumor Necrosis Factor Therapy in Polyarticular Forms of Juvenile Idiopathic Arthritis.

A20: Understanding the Use and Biology of TNF Therapy in JIA-Clinical Outcomes.

A68: The Role of Serum S100A12 Protein Levels in Maintaining Inactive Disease on Anti-tumor Necrosis Factor Therapy in Polyarticular Forms of Juvenile Idiopathic Arthritis.

Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis).

Activated STING in a vascular and pulmonary syndrome.

Monocyte-induced development of Th17 cells and the release of S100 proteins are involved in the pathogenesis of graft-versus-host disease.

Management of juvenile idiopathic arthritis: hitting the target.

Reprogramming of monocytes by GM-CSF contributes to regulatory immune functions during intestinal inflammation.

Single amino acid charge switch defines clinically distinct proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated inflammatory diseases.

Redox distress and genetic defects conspire in systemic autoinflammatory diseases.

MRP8/14 serum levels as a predictor of response to starting and stopping anti-TNF treatment in juvenile idiopathic arthritis.

Detection of Early Murine Colorectal Cancer by MMP-2/-9-Guided Fluorescence Endoscopy.

Increased serum concentrations of neutrophil-derived protein S100A12 in heterozygous carriers of MEFV mutations.

Sleep Fragmentation and Biomarkers in Juvenile Idiopathic Arthritis.

HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.

No association of IL-12p40 pro1.1 polymorphism with juvenile idiopathic arthritis.

[Translational research in pediatric rheumatology. Current research approaches to the innate immune system].

Correlation of Secretory Activity of Neutrophils With Genotype in Patients With Familial Mediterranean Fever.

Review of biomarkers in systemic juvenile idiopathic arthritis: helpful tools or just playing tricks?

Alarmins firing arthritis: Helpful diagnostic tools and promising therapeutic targets.

Partial correction of neutrophil dysfunction by oral galactose therapy in glycogen storage disease type Ib.

Granulocyte Macrophage Colony-Stimulating Factor-Activated CD39+/CD73+ Murine Monocytes Modulate Intestinal Inflammation via Induction of Regulatory T Cells.

Proinflammatory Cytokine Environments Can Drive Interleukin-17 Overexpression by γ/δ T Cells in Systemic Juvenile Idiopathic Arthritis.

Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Munchausen by proxy syndrome mimicking systemic autoinflammatory disease: case report and review of the literature.

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.

S100A12 Is Associated with Response to Therapy in Juvenile Idiopathic Arthritis.

Identification of an Amino Acid Motif in HLA-DRβ1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis.

IL-6 blockade in systemic juvenile idiopathic arthritis - achievement of inactive disease and remission (data from the German AID-registry).

The German version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).

Treating juvenile idiopathic arthritis to target: recommendations of an international task force.

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.

Proteomics in Chronic Arthritis-Will We Finally Have Useful Biomarkers?

Calcium and zinc tune autoinflammatory Toll-like receptor 4 signaling by S100A12.

The role of S100 proteins in the pathogenesis and monitoring of autoinflammatory diseases.

Monocyte-Derived Interleukin-1β As the Driver of S100A12-Induced Sterile Inflammatory Activation of Human Coronary Artery Endothelial Cells: Implications for the Pathogenesis of Kawasaki Disease.

Evaluation of the S100 protein A12 as a biomarker of neonatal sepsis.

Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study.

Molecular signature characterisation of different inflammatory phenotypes of systemic juvenile idiopathic arthritis.

Classification criteria for autoinflammatory recurrent fevers.

The German National Registry of Primary Immunodeficiencies (2012-2017).