Jukka Takala

Department of Intensive Care Medicine, University and Bern University Hospital (Inselspital)

Affiliated withUniversity and Bern University Hospital (Inselspital)

Research Area

Medicine

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2014

Other Publications

Article	Year
Delayed heart perforation after blunt trauma. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 11788280	2002
Dangers of growth hormone therapy in critically ill patients. Current opinion in clinical nutrition and metabolic care\| PubMed ID: 11844988	2002
ARDS. Monitoring tissue perfusion. Critical care clinics\| PubMed ID: 11910727	2002
Effect of dopamine-induced changes in splanchnic blood flow on MEGX production from lidocaine in septic and cardiac surgery patients. Shock (Augusta, Ga.)\| PubMed ID: 12095126	2002
Effects of dopamine on systemic and regional blood flow and metabolism in septic and cardiac surgery patients. Shock (Augusta, Ga.)\| PubMed ID: 12095139	2002
Jejunal luminal microdialysate lactate in cardiac tamponade--effect of low systemic blood flow on gut mucosa. Intensive care medicine\| PubMed ID: 12122536	2002
Splanchnic vasoregulation during mesenteric ischemia and reperfusion in pigs. Shock (Augusta, Ga.)\| PubMed ID: 12166777	2002
Safe long-distance interhospital ground transfer of critically ill patients with acute severe unstable respiratory and circulatory failure. Intensive care medicine\| PubMed ID: 12185435	2002
Change in stroke volume in response to fluid challenge: assessment using esophageal Doppler. Intensive care medicine\| PubMed ID: 12684746	2003
Pulmonary capillary pressure. Intensive care medicine\| PubMed ID: 12736776	2003
Changes in regional blood flow and pCO(2) gradients during isolated abdominal aortic blood flow reduction. Intensive care medicine\| PubMed ID: 13680116	2003
Pulmonary capillary pressures during the acute respiratory distress syndrome. Intensive care medicine\| PubMed ID: 14586495	2003
Diagnosis and management of electrolyte emergencies. Best practice & research. Clinical endocrinology & metabolism\| PubMed ID: 14687593	2003
Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients w... Critical care medicine\| PubMed ID: 14707554	2004
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Critical care medicine\| PubMed ID: 14707556	2004
Severe hypercapnia due to pulmonary embolism of polymethylmethacrylate during vertebroplasty. Anesthesia and analgesia\| PubMed ID: 15041623	2004
Changes in splanchnic circulation during an alveolar recruitment maneuver in healthy porcine lungs. Anesthesia and analgesia\| PubMed ID: 15105226	2004
A european, multicenter, observational study to assess the value of gastric-to-end tidal PCO2 difference in predicting postoperative complications. Anesthesia and analgesia\| PubMed ID: 15281524	2004
Measuring depth of sedation with auditory evoked potentials during controlled infusion of propofol and remifentanil in healthy volunteers. Anesthesia and analgesia\| PubMed ID: 15562062	2004
Estimation of central venous pressure by ultrasound. Resuscitation\| PubMed ID: 15680529	2005
Hepatosplanchnic blood flow control and oxygen extraction are modified by the underlying mechanism of impaired perfusion. Critical care medicine\| PubMed ID: 15753759	2005
Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment. Blood\| PubMed ID: 15827126	2005
Comparison of continuous and intermittent renal replacement therapy for acute renal failure. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association\| PubMed ID: 15886217	2005
High-frequency ventilation versus conventional ventilation for the treatment of acute lung injury and acute respiratory distress syndrome: a systematic review and cochrane analysis. Anesthesia and analgesia\| PubMed ID: 15920211	2005
Does fluid loading influence measurements of intestinal permeability? Critical care (London, England)\| PubMed ID: 15987395	2005
Severe transfusion-related acute lung injury. Anesthesia and analgesia\| PubMed ID: 16037167	2005
Moving knowledge of global burden into preventive action. American journal of industrial medicine\| PubMed ID: 16299702	2005
Review of estimates of the global burden of injury and illness due to occupational exposures. American journal of industrial medicine\| PubMed ID: 16299705	2005
Highs and lows in high-risk surgery: the controversy of goal-directed haemodynamic management. Critical care (London, England)\| PubMed ID: 16356256	2005
Tracheal tear and tension pneumothorax complicating bronchoscopy-guided percutaneous tracheostomy. Heart & lung : the journal of critical care\| PubMed ID: 16543045	2006
A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive ca... Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 16619152	2006
Effects of low abdominal blood flow and dobutamine on blood flow distribution and on the hepatic arterial buffer response in anaesthetized pigs. Shock (Augusta, Ga.)\| PubMed ID: 16670644	2006
Ethicalization in bioscience--a pilot study in Finland. Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees\| PubMed ID: 16862930	2006
Decreasing gut wall glucose as an early marker of impaired intestinal perfusion. Critical care medicine\| PubMed ID: 16878039	2006
Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function. Critical care (London, England)\| PubMed ID: 16895596	2006
Membrane microdialysis: Evaluation of a new method to assess splanchnic tissue metabolism. Critical care medicine\| PubMed ID: 16915109	2006
The pulmonary artery catheter: the tool versus treatments based on the tool. Critical care (London, England)\| PubMed ID: 16953899	2006
Recent trends in ILO conventions related to occupational safety and health. International journal of occupational safety and ergonomics : JOSE\| PubMed ID: 16984785	2006
The effects of dexmedetomidine/remifentanil and midazolam/remifentanil on auditory-evoked potentials and electroencephalogram at light-to-moderate sedation levels in healthy subjects. Anesthesia and analgesia\| PubMed ID: 17056949	2006
Causes of death and determinants of outcome in critically ill patients. Critical care (London, England)\| PubMed ID: 17083735	2006
Global estimates of fatal work-related diseases. American journal of industrial medicine\| PubMed ID: 17154410	2007
Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study. Critical care (London, England)\| PubMed ID: 17212816	2007
Effect of endotoxin, dobutamine and dopamine on muscle mitochondrial respiration in vitro. Journal of endotoxin research\| PubMed ID: 17254390	2006
The ratification status of ILO conventions related to occupational safety and health and its relationship with reported occupational fatality rates. Journal of occupational health\| PubMed ID: 17314469	2007
Hypoxemia due to increased venous admixture: influence of cardiac output on oxygenation. Intensive care medicine\| PubMed ID: 17342520	2007
Effects of vasopressin on microcirculatory blood flow in the gastrointestinal tract in anesthetized pigs in septic shock. Anesthesiology\| PubMed ID: 17525591	2007
Variability in outcome and resource use in intensive care units. Intensive care medicine\| PubMed ID: 17541552	2007
Intraperitoneal microdialysis: critique of an editorial. Critical care medicine\| PubMed ID: 17581382	2007
Hemodynamic management of the critically ill patient: craft meets science. Current opinion in critical care\| PubMed ID: 17762229	2007
Sedation and weaning from mechanical ventilation: effects of process optimization outside a clinical trial. Journal of critical care\| PubMed ID: 17869972	2007
Tonometry revisited: perfusion-related, metabolic, and respiratory components of gastric mucosal acidosis in acute cardiorespiratory failure. Shock (Augusta, Ga.)\| PubMed ID: 18004228	2008
Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow. Critical care (London, England)\| PubMed ID: 18078508	2007
Early prognostic value of the medical emergency team calling criteria in patients admitted to intensive care from the emergency department. Critical care medicine\| PubMed ID: 18209673	2008
The immediate and sustained effects of volume challenge on regional blood flows in pigs. Anesthesia and analgesia\| PubMed ID: 18227321	2008
Development and simultaneous application of multiple care protocols in critical care: a multicenter feasibility study. Intensive care medicine\| PubMed ID: 18385977	2008
Outcome after acute traumatic subdural and epidural haematoma in Switzerland: a single-centre experience. Swiss medical weekly\| PubMed ID: 18491241	2008
Orthogonal polarization spectroscopy to detect mesenteric hypoperfusion. Intensive care medicine\| PubMed ID: 18516589	2008
Resource use and outcome in critically ill patients with hematological malignancy: a retrospective cohort study. Critical care (London, England)\| PubMed ID: 18538003	2008
Thermodilution and esophageal Doppler ultrasound in the assessment of blood flow changes induced by endotoxin and dobutamine. The Journal of trauma\| PubMed ID: 18580513	2008
Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Critical care (London, England)\| PubMed ID: 18625036	2008
Can outcome prediction data change patient outcomes and organizational outcomes? Current opinion in critical care\| PubMed ID: 18787442	2008
Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive care medicine\| PubMed ID: 18795253	2009
Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study. Critical care (London, England)\| PubMed ID: 18796156	2008
The pulmonary artery catheter: in medio virtus. Critical care medicine\| PubMed ID: 18824901	2008
Science, medicine and industry: are we getting out of the black hole in sepsis research? Intensive care medicine\| PubMed ID: 18839139	2008
Inverse thermodilution with conventional pulmonary artery catheters for the assessment of cerebral, hepatic, renal, and femoral blood flow. Shock (Augusta, Ga.)\| PubMed ID: 19033887	2009
Better conduct of clinical trials: the control group in critical care trials. Critical care medicine\| PubMed ID: 19104230	2009
Increased splanchnic oxygen extraction because of routine nursing procedures. Critical care medicine\| PubMed ID: 19114883	2009
Shedding light on microcirculation? Intensive care medicine\| PubMed ID: 19125231	2009
Arterial blood pressure during early sepsis and outcome. Intensive care medicine\| PubMed ID: 19189077	2009
Intra- and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventiona... Critical care (London, England)\| PubMed ID: 19228415	2009
Assessment of splanchnic blood flow using magnetic resonance imaging. European journal of gastroenterology & hepatology\| PubMed ID: 19293721	2009
Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock (Augusta, Ga.)\| PubMed ID: 19295491	2009
Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study. Critical care (London, England)\| PubMed ID: 19331653	2009
Norepinephrine-induced hypertension dilates vasospastic basilar artery after subarachnoid haemorrhage in rabbits. Acta neurochirurgica\| PubMed ID: 19343267	2009
Global trend according to estimated number of occupational accidents and fatal work-related diseases at region and country level. Journal of safety research\| PubMed ID: 19433205	2009
Physical and occupational therapy during sedation stops. Lancet\| PubMed ID: 19446327	2009
Peri-operative adrenocortical response to low-dose (1 microg) ACTH and relation to postoperative complications in patients undergoing elective abdominal surgery. Surgery\| PubMed ID: 19541014	2009
Effects of endotoxin and catecholamines on hepatic mitochondrial respiration. Inflammation\| PubMed ID: 19603262	2009
Auditory event-related potentials, bispectral index, and entropy for the discrimination of different levels of sedation in intensive care unit patients. Anesthesia and analgesia\| PubMed ID: 19690250	2009
Hypoxia inducible factor-1 alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver international : official journal of the International Association for the Study of the Liver\| PubMed ID: 19744167	2009
Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure. Intensive care medicine\| PubMed ID: 19760204	2010
Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study. Critical care (London, England)\| PubMed ID: 19799772	2009
When drugs disappear from the patient: elimination of intravenous medication by hemodiafiltration. Anesthesia and analgesia\| PubMed ID: 19843802	2009
Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Critical care (London, England)\| PubMed ID: 19917106	2009
Effect of fluid resuscitation on mortality and organ function in experimental sepsis models. Critical care (London, England)\| PubMed ID: 19930656	2009
Effects of lung recruitment maneuvers on splanchnic organ perfusion during endotoxin-induced pulmonary arterial hypertension. Shock (Augusta, Ga.)\| PubMed ID: 20357696	2010
Splanchnic vasoregulation after major abdominal surgery in pigs. World journal of surgery\| PubMed ID: 20383500	2010
Physiologic response to changing positive end-expiratory pressure during neurally adjusted ventilatory assist in sedated, critically ill adults. Chest\| PubMed ID: 20435654	2010
Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions. PloS one\| PubMed ID: 20539755	2010
Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study. Critical care (London, England)\| PubMed ID: 20540730	2010
Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study. Critical care (London, England)\| PubMed ID: 20576099	2010
Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures. BMC gastroenterology\| PubMed ID: 20598159	2010
Extra-intracranial blood shunt mimicking aneurysm rupture: intracranial-pressure-controlled rabbit subarachnoid hemorrhage model. Journal of neuroscience methods\| PubMed ID: 20624427	2010
Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion\| PubMed ID: 20691286	2011
Brain herniation in a patient with apparently normal intracranial pressure: a case report. Journal of medical case reports\| PubMed ID: 20807427	2010
Current approach to the haemodynamic management of septic shock patients in European intensive care units: a cross-sectional, self-reported questionnaire-based survey. European journal of anaesthesiology\| PubMed ID: 21088597	2011
Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm. Acta neurochirurgica. Supplement\| PubMed ID: 21116933	2011
Should we target blood pressure in sepsis? Critical care medicine\| PubMed ID: 21164405	2010
Influenza A(H1N1) infection and severe cardiac dysfunction in adults: A case series. Wiener klinische Wochenschrift\| PubMed ID: 21240687	2011
Risk assessment in the first fifteen minutes: a prospective cohort study of a simple physiological scoring system in the emergency department. Critical care (London, England)\| PubMed ID: 21244659	2011
Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest. Resuscitation\| PubMed ID: 21292380	2011
Hydroxyethyl starches: what do we still know? Anesthesia and analgesia\| PubMed ID: 21296859	2011
Global estimates of fatal work-related diseases by region and disease group, 2002. International journal of occupational and environmental health\| PubMed ID: 21344819	2011
Surgery: risky business? Anesthesia and analgesia\| PubMed ID: 21430031	2011
CO(2)-Dependent vasomotor reactivity of cerebral arteries in patients with severe traumatic brain injury: time course and effect of augmentation of cardiac output with dobutamine. Journal of neurotrauma\| PubMed ID: 21501044	2012
Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs. Innate immunity\| PubMed ID: 21525237	2012
Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: a multi-center randomized controlled trial. Critical care (London, England)\| PubMed ID: 21676229	2011
Identification of adequate neurally adjusted ventilatory assist (NAVA) during systematic increases in the NAVA level. IEEE transactions on bio-medical engineering\| PubMed ID: 21690003	2011
Postoperative splanchnic blood flow redistribution in response to fluid challenges in the presence and absence of endotoxemia in a porcine model. Shock (Augusta, Ga.)\| PubMed ID: 21993445	2012
Neurally adjusted ventilatory assist in patients with critical illness-associated polyneuromyopathy. Intensive care medicine\| PubMed ID: 22048718	2011
Impact of reimbursement schemes on quality of care: a European perspective. American journal of respiratory and critical care medicine\| PubMed ID: 22246700	2012
Hemodynamic support: focus on monitoring tools or treatments? Critical care medicine\| PubMed ID: 22425842	2012
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA\| PubMed ID: 22436955	2012
Effects of cardiac preload reduction and dobutamine on hepatosplanchnic blood flow regulation in porcine endotoxemia. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 22556139	2012
A new rabbit model for the study of early brain injury after subarachnoid hemorrhage. Journal of neuroscience methods\| PubMed ID: 22595025	2012
Randomized, double-blind trial of the effect of fluid composition on electrolyte, acid-base, and fluid homeostasis in patients early after subarachnoid hemorrhage. Neurocritical care\| PubMed ID: 22872427	2013
Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Critical care medicine\| PubMed ID: 22890256	2012
Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PloS one\| PubMed ID: 23028840	2012
Haemodynamic variables and functional outcome in hypothermic patients following out-of-hospital cardiac arrest. Resuscitation\| PubMed ID: 23092896	2013
Continuous flow left ventricular assist devices: a valid option for heart failure patients. Swiss medical weekly\| PubMed ID: 23135811	2012
Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Critical care (London, England)\| PubMed ID: 23363690	2013
Mitochondrial function in sepsis. European journal of clinical investigation\| PubMed ID: 23496374	2013
Target blood pressure in sepsis: between a rock and a hard place. Critical care (London, England)\| PubMed ID: 23692986	2013
Intensive care sedation: the past, present and the future. Critical care (London, England)\| PubMed ID: 23758942	2013
Hemodynamic assessment of critically ill patients using a miniaturized transesophageal echocardiography probe. Critical care (London, England)\| PubMed ID: 23786797	2013
Safety of modern starches used during surgery: misleading conclusions. Anesthesia and analgesia\| PubMed ID: 23881375	2013
Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Intensive care medicine\| PubMed ID: 23921976	2013
No evidence for a local renin-angiotensin system in liver mitochondria. Scientific reports\| PubMed ID: 23959064	2013
Sedation level and prevalence of delirium: response to Brummel and Ely. Intensive care medicine\| PubMed ID: 24061632	2014
Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Critical care (London, England)\| PubMed ID: 24103466	2013
Global estimates of the burden of injury and illness at work in 2012. Journal of occupational and environmental hygiene\| PubMed ID: 24219404	2014
Different contribution of splanchnic organs to hyperlactatemia in fecal peritonitis and cardiac tamponade. BioMed research international\| PubMed ID: 24228242	2013
Left ventricular torsion abnormalities in septic shock and corrective effect of volume loading: a pilot study. The Canadian journal of cardiology\| PubMed ID: 24267806	2013
Night-time intensivists - waste of resources or failure of process optimization? Critical care (London, England)\| PubMed ID: 24369938	2013
Of delirium and sedation. American journal of respiratory and critical care medicine\| PubMed ID: 24628309	2014
Angiotensin II in septic shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Critical care medicine\| PubMed ID: 24797374	2014
Clinical significance of monitoring perfusion in non-vital organs. Intensive care medicine\| PubMed ID: 24871502	2014
Reply: Is the glass of delirium half full or half empty? American journal of respiratory and critical care medicine\| PubMed ID: 24881945	2014
Interference of angiotensin II and enalapril with hepatic blood flow regulation. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 25059826	2014
Early changes of muscle membrane properties in porcine faecal peritonitis. Critical care (London, England)\| PubMed ID: 25145497	2014
Biatrial enlargement: 6,000 ml intracardiac blood volume. Intensive care medicine\| PubMed ID: 25183566	2014
Heart-lung interactions during neurally adjusted ventilatory assist. Critical care (London, England)\| PubMed ID: 25212533	2014