Tongguang Wang

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation.

Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.

Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures.

Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.

3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

Protective effect of dextromethorphan against endotoxic shock in mice.

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.

MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.

Viruses and the brain: from inflammation to dementia.

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor.

Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.

3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.

Interleukin-17 in transverse myelitis and multiple sclerosis.

Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers.

Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease.

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.

Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.

Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation.

Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation.

Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses.

Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β.

Isoform-specific cleavage of neuroligin-3 reduces synapse strength.

Activated T cells induce proliferation of oligodendrocyte progenitor cells via release of vascular endothelial cell growth factor-A.

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway.

Response of human macrophages to gamma radiation is mediated via expression of endogenous retroviruses.

Retroviral Elements in Human Evolution and Neural Development.

SMARCB1 deletion in atypical teratoid rhabdoid tumors results in human endogenous retrovirus K (HML-2) expression.

Fluconazole Is Neuroprotective via Interactions with the IGF-1 Receptor.

Retrotransposon insertions associated with risk of neurologic and psychiatric diseases.

Human stem cells hold the key to the study of human neural infectious disorders.

Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.

Building a growing genomic repository for maternal and fetal health through the PING Consortium.