Tongguang Wang

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation.

Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase.

Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures.

Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.

3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

Protective effect of dextromethorphan against endotoxic shock in mice.

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage.

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.

MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.

Viruses and the brain: from inflammation to dementia.

Granzyme B mediates neurotoxicity through a G-protein-coupled receptor.

Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.

3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro.

Interleukin-17 in transverse myelitis and multiple sclerosis.

Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers.

Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease.

HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.

Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.

Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation.

Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation.