Alessio Accardi

Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.

A biological role for prokaryotic ClC chloride channels.

Mechanisms of block of muscle type CLC chloride channels (Review).

Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.

Conformational changes in the pore of CLC-0.

Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.

Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.

Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.

Separate ion pathways in a Cl-/H+ exchanger.

Synergism between halide binding and proton transport in a CLC-type exchanger.

Uncoupling and turnover in a Cl-/H+ exchange transporter.

To ATP or not to ATP: this is the question.

Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.

Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.

CLC channels and transporters: proteins with borderline personalities.

Proton block of the CLC-5 Cl-/H+ exchanger.

A dystroglycan mutation associated with limb-girdle muscular dystrophy.

PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.

Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.

Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.

Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.

Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.

Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.

TMEM16 proteins: unknown structure and confusing functions.

Unveiling the secret lives of glutamate transporters: VGLUTs engage in multiple transport modes.