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Department of Anesthesiology,
Department of Physiology and Biophysics,
Department of Biochemistry
Alessio Accardi has not added Biography.
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Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.
Molecular pharmacology Aug, 2002 | Pubmed ID: 12130677
A biological role for prokaryotic ClC chloride channels.
Nature Oct, 2002 | Pubmed ID: 12384697
Mechanisms of block of muscle type CLC chloride channels (Review).
Molecular membrane biology Oct-Dec, 2002 | Pubmed ID: 12512775
Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.
Neuron Apr, 2003 | Pubmed ID: 12691663
Conformational changes in the pore of CLC-0.
The Journal of general physiology Sep, 2003 | Pubmed ID: 12913090
Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2003 | Pubmed ID: 14569011
Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.
The Journal of general physiology Feb, 2004 | Pubmed ID: 14718478
Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels.
Nature Feb, 2004 | Pubmed ID: 14985752
Separate ion pathways in a Cl-/H+ exchanger.
The Journal of general physiology Dec, 2005 | Pubmed ID: 16316975
Synergism between halide binding and proton transport in a CLC-type exchanger.
Journal of molecular biology Sep, 2006 | Pubmed ID: 16949616
Uncoupling and turnover in a Cl-/H+ exchange transporter.
The Journal of general physiology Apr, 2007 | Pubmed ID: 17389248
To ATP or not to ATP: this is the question.
The Journal of general physiology Feb, 2008 | Pubmed ID: 18227270
Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2008 | Pubmed ID: 18678918
Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.
Nature structural & molecular biology Dec, 2009 | Pubmed ID: 19898476
CLC channels and transporters: proteins with borderline personalities.
Biochimica et biophysica acta Aug, 2010 | Pubmed ID: 20188062
Proton block of the CLC-5 Cl-/H+ exchanger.
The Journal of general physiology Jun, 2010 | Pubmed ID: 20513761
A dystroglycan mutation associated with limb-girdle muscular dystrophy.
The New England journal of medicine Mar, 2011 | Pubmed ID: 21388311
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2011 | Pubmed ID: 21753018
Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H(+)/Cl(-) exchanger.
Nature structural & molecular biology May, 2012 | Pubmed ID: 22484316
Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.
Nature communications , 2013 | Pubmed ID: 23996062
Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2013 | Pubmed ID: 24167264
Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.
Nature structural & molecular biology May, 2014 | Pubmed ID: 24747941
Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
The Biochemical journal Nov, 2014 | Pubmed ID: 25184538
TMEM16 proteins: unknown structure and confusing functions.
Journal of molecular biology Jan, 2015 | Pubmed ID: 25451786
Unveiling the secret lives of glutamate transporters: VGLUTs engage in multiple transport modes.
Neuron Dec, 2014 | Pubmed ID: 25521371
Weill Cornell Medical College
Daniel Basilio1,
Alessio Accardi1,2,3
1Department of Anesthesiology, Weill Cornell Medical College,
2Department of Physiology and Biophysics, Weill Cornell Medical College,
3Department of Biochemistry, Weill Cornell Medical College
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