Oncology
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Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences.
Journal of cellular biochemistry , 2002 | Pubmed ID: 11787071
Activated ras regulates the proliferation/apoptosis balance and early survival of developing micrometastases.
Cancer research Feb, 2002 | Pubmed ID: 11830548
Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy.
Cancer research Apr, 2002 | Pubmed ID: 11929839
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling.
Journal of the National Cancer Institute Apr, 2002 | Pubmed ID: 11929952
Dissemination and growth of cancer cells in metastatic sites.
Nature reviews. Cancer Aug, 2002 | Pubmed ID: 12154349
Plasma osteopontin: associations with survival and metastasis to bone in men with hormone-refractory prostate carcinoma.
Cancer Aug, 2002 | Pubmed ID: 12209742
Cancer spread and micrometastasis development: quantitative approaches for in vivo models.
BioEssays : news and reviews in molecular, cellular and developmental biology Oct, 2002 | Pubmed ID: 12325121
Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways.
Oncogene Feb, 2003 | Pubmed ID: 12606946
Transcriptional regulation of osteopontin and the metastatic phenotype: evidence for a Ras-activated enhancer in the human OPN promoter.
Clinical & experimental metastasis , 2003 | Pubmed ID: 12650610
Osteopontin and colon cancer progression.
Clinical & experimental metastasis , 2003 | Pubmed ID: 12650611
Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis.
Journal of immunology (Baltimore, Md. : 1950) Jul, 2003 | Pubmed ID: 12847283
Estrous cycle influences organ-specific metastasis of B16F10 melanoma cells.
Cancer research Aug, 2003 | Pubmed ID: 12941790
Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin.
Molecular cancer research : MCR Sep, 2003 | Pubmed ID: 14517343
The role of apoptosis in tumor progression and metastasis.
Current molecular medicine Nov, 2003 | Pubmed ID: 14601637
Evaluating the role of serine protease inhibition in the management of tumor micrometastases.
Oncology (Williston Park, N.Y.) Oct, 2003 | Pubmed ID: 14606367
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases.
Breast cancer research and treatment Dec, 2003 | Pubmed ID: 14703067
Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2004 | Pubmed ID: 14734468
Osteopontin identified as colon cancer tumor progression marker.
Comptes rendus biologies Oct-Nov, 2003 | Pubmed ID: 14744111
Surface-enhanced laser desorption/ionization-time of flight-mass spectrometry (SELDI-TOF-MS): a new proteomic urinary test for patients with urolithiasis.
Journal of clinical laboratory analysis , 2004 | Pubmed ID: 15103681
A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines.
The Journal of nutrition Jun, 2004 | Pubmed ID: 15173424
Mapping of the functional microcirculation in vital organs using contrast-enhanced in vivo video microscopy.
American journal of physiology. Heart and circulatory physiology Jan, 2005 | Pubmed ID: 15388500
In vivo videomicroscopy reveals differential effects of the vascular-targeting agent ZD6126 and the anti-angiogenic agent ZD6474 on vascular function in a liver metastasis model.
Angiogenesis , 2004 | Pubmed ID: 15516836
Therapeutic targets for antimetastatic therapy.
Expert opinion on therapeutic targets Dec, 2004 | Pubmed ID: 15584860
Detection and quantification of circulating tumor cells in mouse models of human breast cancer using immunomagnetic enrichment and multiparameter flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology May, 2005 | Pubmed ID: 15810015
Dietary genistein reduces metastasis in a postsurgical orthotopic breast cancer model.
Cancer research Apr, 2005 | Pubmed ID: 15833874
Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression.
Molecular carcinogenesis Aug, 2005 | Pubmed ID: 15864800
Three-dimensional high-frequency ultrasound imaging for longitudinal evaluation of liver metastases in preclinical models.
Cancer research Jun, 2005 | Pubmed ID: 15958568
Re: Medroxyprogesterone acetate and metastases: of mice and (wo)men.
Journal of the National Cancer Institute Aug, 2005 | Pubmed ID: 16106028
Plasma osteopontin levels are predictive of disease stage in patients with transitional cell carcinoma of the bladder.
BJU international Oct, 2005 | Pubmed ID: 16153205
A new model for lymphatic metastasis: development of a variant of the MDA-MB-468 human breast cancer cell line that aggressively metastasizes to lymph nodes.
Clinical & experimental metastasis , 2005 | Pubmed ID: 16170671
Expression of osteopontin and HGF/met in adult soft tissue tumors.
Cancer biology & therapy Dec, 2005 | Pubmed ID: 16258259
In vivo magnetic resonance imaging of single cells in mouse brain with optical validation.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Jan, 2006 | Pubmed ID: 16342157
Ovarian cancer biomarkers in urine.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2006 | Pubmed ID: 16428467
Time-course characterization of the computed tomography contrast enhancement of an iodinated blood-pool contrast agent in mice using a volumetric flat-panel equipped computed tomography scanner.
Investigative radiology Apr, 2006 | Pubmed ID: 16523021
Enhanced cell surface CD44 variant (v6, v9) expression by osteopontin in breast cancer epithelial cells facilitates tumor cell migration: novel post-transcriptional, post-translational regulation.
Clinical & experimental metastasis , 2005 | Pubmed ID: 16691370
Serial plasma osteopontin levels have prognostic value in metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Jun, 2006 | Pubmed ID: 16740755
Molecular mechanisms of metastasis.
Cancer metastasis reviews Jun, 2006 | Pubmed ID: 16770533
Osteopontin induction of hyaluronan synthase 2 expression promotes breast cancer malignancy.
The Journal of biological chemistry Aug, 2006 | Pubmed ID: 16807238
Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer.
The American journal of pathology Jul, 2006 | Pubmed ID: 16816376
Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435.
Clinical & experimental metastasis , 2006 | Pubmed ID: 16830223
Dormancy of solitary metastatic cells.
Cell cycle (Georgetown, Tex.) Aug, 2006 | Pubmed ID: 16861927
Breast cancer metastasis progression as revealed by intravital videomicroscopy.
Expert review of anticancer therapy Sep, 2006 | Pubmed ID: 17020460
Tumor dormancy and the role of metastasis suppressor genes in regulating ectopic growth.
Future oncology (London, England) Oct, 2006 | Pubmed ID: 17026454
In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Nov, 2006 | Pubmed ID: 17029229
In vivo inhibition of growth of human tumor lines by flavonoid fractions from cranberry extract.
Nutrition and cancer , 2006 | Pubmed ID: 17176222
Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kappaB activation.
Molecular cancer , 2007 | Pubmed ID: 17227585
The biology of metastasis to a sanctuary site.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2007 | Pubmed ID: 17363518
Tumor dormancy and cancer stem cells: implications for the biology and treatment of breast cancer metastasis.
Breast disease , 2006-2007 | Pubmed ID: 17473368
Brain metastases of breast cancer.
Breast disease , 2006-2007 | Pubmed ID: 17473372
Tumour dormancy in breast cancer: an update.
Breast cancer research : BCR , 2007 | Pubmed ID: 17561992
Osteopontin overexpression in breast cancer: knowledge gained and possible implications for clinical management.
Journal of cellular biochemistry Nov, 2007 | Pubmed ID: 17721886
Osteopontin expression in normal skin and non-melanoma skin tumors.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Jan, 2008 | Pubmed ID: 17938278
A new breast cancer model for lymphatic metastasis.
Cancer treatment and research , 2007 | Pubmed ID: 17953414
Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo.
Molecular therapy : the journal of the American Society of Gene Therapy Jan, 2008 | Pubmed ID: 17998900
The thrombin inhibitor Argatroban reduces breast cancer malignancy and metastasis via osteopontin-dependent and osteopontin-independent mechanisms.
Breast cancer research and treatment Nov, 2008 | Pubmed ID: 18097747
Noninvasive quantification of tumor volume in preclinical liver metastasis models using contrast-enhanced x-ray computed tomography.
Investigative radiology Feb, 2008 | Pubmed ID: 18197061
Experimental metastasis assays in the chick embryo.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] Feb, 2004 | Pubmed ID: 18228449
Molecular cytogenetic characterization of human breast cancer cell line MDA-MB-468 and its variant 468LN, which displays aggressive lymphatic metastasis.
Cancer genetics and cytogenetics Feb, 2008 | Pubmed ID: 18262045
Influence of diet on metastasis and tumor dormancy.
Clinical & experimental metastasis , 2009 | Pubmed ID: 18386136
Changes over time of extracellular domain of HER2 (ECD/HER2) serum levels have prognostic value in metastatic breast cancer.
Breast cancer research and treatment Apr, 2009 | Pubmed ID: 18437556
Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1.
International journal of cancer. Journal international du cancer Aug, 2008 | Pubmed ID: 18470911
BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation.
Clinical & experimental metastasis , 2008 | Pubmed ID: 18543067
Contrast-enhanced microcomputed tomography using intraperitoneal contrast injection for the assessment of tumor-burden in liver metastasis models.
Investigative radiology Jul, 2008 | Pubmed ID: 18580331
Ex-vivo cellular MRI with b-SSFP: quantitative benefits of 3T over 1.5 T.
Magma (New York, N.Y.) Jul, 2008 | Pubmed ID: 18581153
Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays.
Breast cancer research : BCR , 2008 | Pubmed ID: 18638373
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.
Cancer research Aug, 2008 | Pubmed ID: 18676848
Distinct karyotypes in three breast cancer cell lines --21PTCi, 21NTCi, and 21MT-1 --derived from the same patient and representing different stages of tumor progression.
Cancer genetics and cytogenetics Oct, 2008 | Pubmed ID: 18786440
New clinical and experimental approaches for studying tumor dormancy: does tumor dormancy offer a therapeutic target?
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica Jul-Aug, 2008 | Pubmed ID: 18834402
Introduction to special issue on 'epigenetic and physiological regulation of metastasis'.
Clinical & experimental metastasis , 2009 | Pubmed ID: 18925360
Chapter 9. Intravital videomicroscopy in angiogenesis research.
Methods in enzymology , 2008 | Pubmed ID: 19007666
Effect of anti-fibrinolytic therapy on experimental melanoma metastasis.
Clinical & experimental metastasis , 2009 | Pubmed ID: 19082867
Putative growth characteristics of micrometastatic breast cancer.
Breast cancer research : BCR , 2008 | Pubmed ID: 19090969
New dual monoclonal ELISA for measuring plasma osteopontin as a biomarker associated with survival in prostate cancer: clinical validation and comparison of multiple ELISAs.
Clinical chemistry May, 2009 | Pubmed ID: 19325010
MDA-MB-435 and M14 cell lines: identical but not M14 melanoma?
Cancer research Jul, 2009 | Pubmed ID: 19549886
Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment.
International journal of oncology Aug, 2009 | Pubmed ID: 19578743
Tumor dormancy and metastasis.
Advances in cancer research , 2009 | Pubmed ID: 19595307
Micrometastatic disease and metastatic outgrowth: clinical issues and experimental approaches.
Future oncology (London, England) Sep, 2009 | Pubmed ID: 19792975
Three-dimensional imaging and quantification of both solitary cells and metastases in whole mouse liver by magnetic resonance imaging.
Cancer research Nov, 2009 | Pubmed ID: 19843857
Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number.
PloS one , 2010 | Pubmed ID: 20084286
Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth.
European journal of cancer (Oxford, England : 1990) May, 2010 | Pubmed ID: 20304630
Human 21T breast epithelial cell lines mimic breast cancer progression in vivo and in vitro and show stage-specific gene expression patterns.
Laboratory investigation; a journal of technical methods and pathology Aug, 2010 | Pubmed ID: 20458274
Role of the metastasis-promoting protein osteopontin in the tumour microenvironment.
Journal of cellular and molecular medicine Aug, 2010 | Pubmed ID: 20597997
Does tumour dormancy offer a therapeutic target?
Nature reviews. Cancer Dec, 2010 | Pubmed ID: 21048784
The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis.
Clinical & experimental metastasis Mar, 2011 | Pubmed ID: 21234655
Gene signatures of breast cancer progression and metastasis.
Breast cancer research : BCR , 2011 | Pubmed ID: 21345283
Nuclear localization of maspin is essential for its inhibition of tumor growth and metastasis.
Laboratory investigation; a journal of technical methods and pathology Aug, 2011 | Pubmed ID: 21502940
Pre- and post-translational regulation of osteopontin in cancer.
Journal of cell communication and signaling Jun, 2011 | Pubmed ID: 21516514
Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer.
Molecular cancer research : MCR Jul, 2011 | Pubmed ID: 21665937
In vivo single scan detection of both iron-labeled cells and breast cancer metastases in the mouse brain using balanced steady-state free precession imaging at 1.5 T.
Journal of magnetic resonance imaging : JMRI Jul, 2011 | Pubmed ID: 21698713
In vivo characterization of changing blood-tumor barrier permeability in a mouse model of breast cancer metastasis: a complementary magnetic resonance imaging approach.
Investigative radiology Nov, 2011 | Pubmed ID: 21788908
Osteopontin increases breast cancer cell sensitivity to specific signaling pathway inhibitors in preclinical models.
Cancer biology & therapy Oct, 2011 | Pubmed ID: 21795853
Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line.
International journal of cancer. Journal international du cancer Jul, 2012 | Pubmed ID: 21823118
β1-integrin: a potential therapeutic target in the battle against cancer recurrence.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2011 | Pubmed ID: 21900388
An emerging role for the nuclear localization of maspin in the suppression of tumor progression and metastasis (1) (1) This article is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal's usual peer review process.
Biochemistry and cell biology = Biochimie et biologie cellulaire Nov, 2011 | Pubmed ID: 22047058
Imaging the impact of chemically inducible proteins on cellular dynamics in vivo.
PloS one , 2012 | Pubmed ID: 22276156
Co-expression of α9β1 integrin and VEGF-D confers lymphatic metastatic ability to a human breast cancer cell line MDA-MB-468LN.
PloS one , 2012 | Pubmed ID: 22545097
Assessing cancer cell migration and metastatic growth in vivo in the chick embryo using fluorescence intravital imaging.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22700400
In Vivo Magnetic Resonance Imaging for Investigating the Development and Distribution of Experimental Brain Metastases due to Breast Cancer.
Translational oncology Jun, 2012 | Pubmed ID: 22741041
Brain metastases from breast cancer: lessons from experimental magnetic resonance imaging studies and clinical implications.
Journal of molecular medicine (Berlin, Germany) Jan, 2014 | Pubmed ID: 24306136
Hypoxia promotes tumor cell motility via RhoA and ROCK1 signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2014 | Pubmed ID: 24398519
Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial.
Breast cancer research : BCR , 2014 | Pubmed ID: 24451146
Radiation-induced lung injury after concurrent neoadjuvant chemoradiotherapy for locally advanced breast cancer.
Acta oncologica (Stockholm, Sweden) May, 2014 | Pubmed ID: 24456500
A method to validate quantitative high-frequency power doppler ultrasound with fluorescence in vivo video microscopy.
Ultrasound in medicine & biology Aug, 2014 | Pubmed ID: 24798391
Cyclin A2, a novel regulator of EMT.
Cellular and molecular life sciences : CMLS Dec, 2014 | Pubmed ID: 24879294
BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis.
Molecular oncology Dec, 2014 | Pubmed ID: 24974076
Tumor-α9β1 integrin-mediated signaling induces breast cancer growth and lymphatic metastasis via the recruitment of cancer-associated fibroblasts.
Journal of molecular medicine (Berlin, Germany) Dec, 2014 | Pubmed ID: 25099519
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.
Cell reports Sep, 2014 | Pubmed ID: 25176655
Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway.
Scientific reports , 2014 | Pubmed ID: 25204426
An open letter to the FDA and other regulatory agencies: Preclinical drug development must consider the impact on metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2009 | Pubmed ID: 25278743
CORRIGENDUM: Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway.
Scientific reports , 2015 | Pubmed ID: 25613050
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