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Gene Expression Division
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An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.
The Journal of biological chemistry Sep, 2002 | Pubmed ID: 12138096
NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain.
The Journal of biological chemistry Nov, 2003 | Pubmed ID: 12954634
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.
Journal of molecular biology Feb, 2004 | Pubmed ID: 14757047
Coactivators in gene regulation by STAT5.
Vitamins and hormones , 2005 | Pubmed ID: 15727811
Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.
The Journal of biological chemistry Oct, 2005 | Pubmed ID: 16126725
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling.
The EMBO journal Mar, 2006 | Pubmed ID: 16511561
FAD mutants unable to increase neurotoxic Abeta 42 suggest that mutation effects on neurodegeneration may be independent of effects on Abeta.
Journal of neurochemistry May, 2007 | Pubmed ID: 17254019
Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor.
The Journal of biological chemistry Jun, 2007 | Pubmed ID: 17428795
Peptide EphB2/CTF2 generated by the gamma-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-methyl-D-aspartate receptors.
The Journal of biological chemistry Oct, 2009 | Pubmed ID: 19661068
Interaction of STAT6 with its co-activator SRC-1/NCoA-1 is regulated by dephosphorylation of the latter via PP2A.
Nucleic acids research Apr, 2011 | Pubmed ID: 21148148
Bio-Rad Laboratories
Adam M. McCoy1,
Claudia Litterst1,
Michelle L. Collins1,
Luis A. Ugozzoli1
1Gene Expression Division, Bio-Rad Laboratories
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