Henning Urlaub

Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry

Affiliated withMax Planck Institute for Biophysical Chemistry University Medical Center, Göttingen

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2015

Other Publications

Article	Year
A two-tracked approach to analyze RNA-protein crosslinking sites in native, nonlabeled small nuclear ribonucleoprotein particles. Methods (San Diego, Calif.)\| PubMed ID: 12054894	2002
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell\| PubMed ID: 12230974	2002
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. The EMBO journal\| PubMed ID: 12234937	2002
Hierarchical, clustered protein interactions with U4/U6 snRNA: a biochemical role for U4/U6 proteins. The EMBO journal\| PubMed ID: 12374753	2002
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science (New York, N.Y.)\| PubMed ID: 12411573	2002
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12477934	2002
An unusual mechanism of bacterial gene expression revealed for the RNase P protein of Thermus strains. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12719542	2003
Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing. The Journal of biological chemistry\| PubMed ID: 12736260	2003
Analysis of mammalian gene function using small interfering RNAs. Nucleic acids research. Supplement (2001)\| PubMed ID: 14510516	2003
The zinc finger-associated domain of the Drosophila transcription factor grauzone is a novel zinc-coordinating protein-protein interaction module. Structure (London, England : 1993)\| PubMed ID: 14604529	2003
Analysis of site-specific protein-RNA cross-links in isolated RNP complexes, combining affinity selection and mass spectrometry. RNA (New York, N.Y.)\| PubMed ID: 14624009	2003
The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA (New York, N.Y.)\| PubMed ID: 15146077	2004
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. The EMBO journal\| PubMed ID: 15175653	2004
Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding. The Biochemical journal\| PubMed ID: 15279620	2004
Purification, crystallization and preliminary crystallographic data of the m3G cap-binding domain of human snRNP import factor snurportin 1. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 15333938	2004
Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Molecular cell\| PubMed ID: 15574333	2004
Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells. Microbiology (Reading, England)\| PubMed ID: 15632438	2005
Proteomic analysis of reaper 5' untranslated region-interacting factors isolated by tobramycin affinity-selection reveals a role for La antigen in reaper mRNA translation. Proteomics\| PubMed ID: 15789343	2005
Functional analysis of seven genes encoding eight translation initiation factor 4E (eIF4E) isoforms in Drosophila. Mechanisms of development\| PubMed ID: 15804566	2005
Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif. The Journal of biological chemistry\| PubMed ID: 16006558	2005
Identification of novel argonaute-associated proteins. Current biology : CB\| PubMed ID: 16289642	2005
Complete MALDI-ToF MS analysis of cross-linked peptide-RNA oligonucleotides derived from nonlabeled UV-irradiated ribonucleoprotein particles. RNA (New York, N.Y.)\| PubMed ID: 16314460	2005
DDX6 recruits translational silenced human reticulocyte 15-lipoxygenase mRNA to RNP granules. RNA (New York, N.Y.)\| PubMed ID: 20884783	2010
RNA structure and RNA-protein interactions in purified yeast U6 snRNPs. Journal of molecular biology\| PubMed ID: 16410014	2006
Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression. The Journal of biological chemistry\| PubMed ID: 16621800	2006
Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase. RNA (New York, N.Y.)\| PubMed ID: 16790842	2006
Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Molecular and cellular biology\| PubMed ID: 16809785	2006
The Methanothermobacter thermautotrophicus ExoIII homologue Mth212 is a DNA uridine endonuclease. Nucleic acids research\| PubMed ID: 17012282	2006
Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA (New York, N.Y.)\| PubMed ID: 17095540	2007
Molecular anatomy of a trafficking organelle. Cell\| PubMed ID: 17110340	2006
Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nature cell biology\| PubMed ID: 17173041	2007
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO journal\| PubMed ID: 17332742	2007
Detection of protein-RNA crosslinks by NanoLC-ESI-MS/MS using precursor ion scanning and multiple reaction monitoring (MRM) experiments. Journal of the American Society for Mass Spectrometry\| PubMed ID: 17349801	2007
In vitro RNA editing in plant mitochondria does not require added energy. FEBS letters\| PubMed ID: 17531229	2007
Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17601773	2007
Improved identification of enriched peptide RNA cross-links from ribonucleoprotein particles (RNPs) by mass spectrometry. Nucleic acids research\| PubMed ID: 17652325	2007
Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO reports\| PubMed ID: 17932509	2007
Two DEAD-box proteins may be part of RNA-dependent high-molecular-mass protein complexes in Arabidopsis mitochondria. Plant physiology\| PubMed ID: 17951454	2007
GraFix: sample preparation for single-particle electron cryomicroscopy. Nature methods\| PubMed ID: 18157137	2008
'Proteomic basics--sample preparation and separation': the 1st European Summer School in Kloster Neustift, 12-18 August, 2007 Brixen/Bressanone, South Tyrol, Italy. Proteomics\| PubMed ID: 18203264	2008
Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity. Molecular and cellular biology\| PubMed ID: 18285457	2008
Isolation of an active step I spliceosome and composition of its RNP core. Nature\| PubMed ID: 18322460	2008
CASK Functions as a Mg2+-independent neurexin kinase. Cell\| PubMed ID: 18423203	2008
Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome. Nature structural & molecular biology\| PubMed ID: 18425142	2008
Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. Molecular cell\| PubMed ID: 18538659	2008
Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Molecular and cellular biology\| PubMed ID: 18981222	2009
Analyzing RNA-protein crosslinking sites in unlabeled ribonucleoprotein complexes by mass spectrometry. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18982295	2008
Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation. RNA (New York, N.Y.)\| PubMed ID: 19029308	2009
Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis. The Journal of biological chemistry\| PubMed ID: 19038966	2009
SAP18 promotes Krüppel-dependent transcriptional repression by enhancer-specific histone deacetylation. The Journal of biological chemistry\| PubMed ID: 19049982	2009
Structural and functional analysis of the E. coli NusB-S10 transcription antitermination complex. Molecular cell\| PubMed ID: 19111659	2008
Atmospheric pressure free liquid infrared MALDI mass spectrometry: toward a combined ESI/ MALDI-liquid chromatography interface. Analytical chemistry\| PubMed ID: 19125446	2009
The neuropeptidome of Rhodnius prolixus brain. Proteomics\| PubMed ID: 19137558	2009
Enrichment of protein-RNA crosslinks from crude UV-irradiated mixtures for MS analysis by on-line chromatography using titanium dioxide columns. Biopolymers\| PubMed ID: 19140157	2009
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell\| PubMed ID: 19167051	2009
SLP-65 phosphorylation dynamics reveals a functional basis for signal integration by receptor-proximal adaptor proteins. Molecular & cellular proteomics : MCP\| PubMed ID: 19372136	2009
iTRAQ-labeling of in-gel digested proteins for relative quantification. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19544025	2009
SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes. Genes & development\| PubMed ID: 19605687	2009
The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides. The Journal of biological chemistry\| PubMed ID: 19667070	2009
Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography. BMC structural biology\| PubMed ID: 19706171	2009
"ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides. Molecular & cellular proteomics : MCP\| PubMed ID: 19721078	2009
In vivo expression and purification of aptamer-tagged small RNA regulators. Nucleic acids research\| PubMed ID: 19726584	2009
Multimerization and H3K9me3 binding are required for CDYL1b heterochromatin association. The Journal of biological chemistry\| PubMed ID: 19808672	2009
A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells. PloS one\| PubMed ID: 19847302	2009
The B-lymphoid Grb2 interaction code. Immunological reviews\| PubMed ID: 19909361	2009
Proteomic basics - Quantification and post-translational modifications of proteins: The 3rd European summer school in Kloster Neustift. Journal of proteomics\| PubMed ID: 19931431	2009
Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components. Nature structural & molecular biology\| PubMed ID: 19935684	2009
The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Molecular cell\| PubMed ID: 19941820	2009
Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20053882	2010
Essential role of a trypanosome U4-specific Sm core protein in small nuclear ribonucleoprotein assembly and splicing. Eukaryotic cell\| PubMed ID: 20081062	2010
Crystal structure of an intramolecular chaperone mediating triple-beta-helix folding. Nature structural & molecular biology\| PubMed ID: 20118935	2010
Human PRP4 kinase is required for stable tri-snRNP association during spliceosomal B complex formation. Nature structural & molecular biology\| PubMed ID: 20118938	2010
Molecular architecture of the human Prp19/CDC5L complex. Molecular and cellular biology\| PubMed ID: 20176811	2010
A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. The Journal of cell biology\| PubMed ID: 20176924	2010
Determination of protein stoichiometry within protein complexes using absolute quantification and multiple reaction monitoring. Analytical chemistry\| PubMed ID: 20225856	2010
Extraction of proteins from formalin-fixed, paraffin-embedded tissue using the Qproteome extraction technique and preparation of tryptic peptides for liquid chromatography/mass spectrometry ... Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]\| PubMed ID: 20373500	2010
Exon definition complexes contain the tri-snRNP and can be directly converted into B-like precatalytic splicing complexes. Molecular cell\| PubMed ID: 20417601	2010
Mapping the binding site of snurportin 1 on native U1 snRNP by cross-linking and mass spectrometry. Nucleic acids research\| PubMed ID: 20421206	2010
Merging molecular electron microscopy and mass spectrometry by carbon film-assisted endoproteinase digestion. Molecular & cellular proteomics : MCP\| PubMed ID: 20530635	2010
The archaeal Lsm protein binds to small RNAs. The Journal of biological chemistry\| PubMed ID: 20826804	2010
The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique. Nucleic acids research\| PubMed ID: 20852261	2011
Pseudo-neutral-loss scan for selective detection of phosphopeptides and N-glycopeptides using liquid chromatography coupled with a hybrid linear ion-trap/orbitrap mass spectrometer. Proteomics\| PubMed ID: 20925059	2010
Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20926670	2010
A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation. RNA (New York, N.Y.)\| PubMed ID: 20962039	2010
Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. RNA (New York, N.Y.)\| PubMed ID: 20980672	2010
PERILIPIN-dependent control of lipid droplet structure and fat storage in Drosophila. Cell metabolism\| PubMed ID: 21035762	2010
Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic acids research\| PubMed ID: 21071408	2011
7SK small nuclear RNA directly affects HMGA1 function in transcription regulation. Nucleic acids research\| PubMed ID: 21087998	2011
Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA. The Journal of biological chemistry\| PubMed ID: 21220421	2011
Fc gamma receptor IIb modulates the molecular Grb2 interaction network in activated B cells. Cellular signalling\| PubMed ID: 21262349	2011
RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure. Development (Cambridge, England)\| PubMed ID: 21350015	2011
Complex phosphorylation dynamics control the composition of the Syk interactome in B cells. European journal of immunology\| PubMed ID: 21469132	2011
A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS biology\| PubMed ID: 21526221	2011
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis method. Molecular and cellular biology\| PubMed ID: 21536652	2011
Functional proteomics of neuropeptidome dynamics during the feeding process of Rhodnius prolixus. Journal of proteome research\| PubMed ID: 21699238	2011
B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster. Immunity\| PubMed ID: 21703542	2011
Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells. The EMBO journal\| PubMed ID: 21725281	2011
Sumoylation inhibits alpha-synuclein aggregation and toxicity. The Journal of cell biology\| PubMed ID: 21746851	2011
Pabp binds to the osk 3'UTR and specifically contributes to osk mRNA stability and oocyte accumulation. Developmental biology\| PubMed ID: 21782810	2011
The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85. The EMBO journal\| PubMed ID: 21822214	2011
Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns. Molecular & cellular proteomics : MCP\| PubMed ID: 21836164	2011
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nature biotechnology\| PubMed ID: 21909082	2011
Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis. The EMBO journal\| PubMed ID: 21983901	2011
Phosphorylation site localization in peptides by MALDI MS/MS and the Mascot Delta Score. Analytical and bioanalytical chemistry\| PubMed ID: 22038583	2012
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Molecular biology of the cell\| PubMed ID: 22114354	2012
BC1-FMRP interaction is modulated by 2'-O-methylation: RNA-binding activity of the tudor domain and translational regulation at synapses. Nucleic acids research\| PubMed ID: 22238374	2012
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity. Immunity\| PubMed ID: 22265677	2012
Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis. Annals of neurology\| PubMed ID: 22367995	2012
Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. The EMBO journal\| PubMed ID: 22407296	2012
OKB, a novel family of brain-gut neuropeptides from insects. Insect biochemistry and molecular biology\| PubMed ID: 22480496	2012
The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end. Nature structural & molecular biology\| PubMed ID: 22522823	2012
The guanine nucleotide exchange factor Vav2 is a negative regulator of parathyroid hormone receptor/Gq signaling. Molecular pharmacology\| PubMed ID: 22554804	2012
Investigation of protein-RNA interactions by mass spectrometry--Techniques and applications. Journal of proteomics\| PubMed ID: 22575267	2012
Quantitative mass spectrometry-based proteomics: an overview. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22665296	2012
Absolute quantification of proteins using standard peptides and multiple reaction monitoring. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22665306	2012
Identification of endogenous SUMO1 accepter sites by mass spectrometry. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 22665316	2012
Determinants of interaction specificity of the Bacillus subtilis GlcT antitermination protein: functionality and phosphorylation specificity depend on the arrangement of the regulatory domai... The Journal of biological chemistry\| PubMed ID: 22722928	2012
Structure and activity of the only human RNase T2. Nucleic acids research\| PubMed ID: 22735700	2012
Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals. Free radical biology & medicine\| PubMed ID: 22771470	2012
Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion. Nature communications\| PubMed ID: 22871813	2012
Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. EMBO reports\| PubMed ID: 22878415	2012
The claudin Megatrachea protein complex. The Journal of biological chemistry\| PubMed ID: 22930751	2012
The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA. Genes & development\| PubMed ID: 23124066	2012
The human cytomegalovirus DNA polymerase processivity factor UL44 is modified by SUMO in a DNA-dependent manner. PloS one\| PubMed ID: 23166733	2012
Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes. The EMBO journal\| PubMed ID: 23202855	2013
Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants. The Journal of biological chemistry\| PubMed ID: 23209282	2013
In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23213215	2012
The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters. The Journal of biological chemistry\| PubMed ID: 23223229	2013
EF-P is essential for rapid synthesis of proteins containing consecutive proline residues. Science (New York, N.Y.)\| PubMed ID: 23239624	2013
Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry. Molecular & cellular proteomics : MCP\| PubMed ID: 23242554	2013
Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex. PloS one\| PubMed ID: 23285124	2012
Identification of DEAD-box RNA helicase 6 (DDX6) as a cellular modulator of vascular endothelial growth factor expression under hypoxia. The Journal of biological chemistry\| PubMed ID: 23293030	2013
SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression. Nature cell biology\| PubMed ID: 23314863	2013
Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes. Nature communications\| PubMed ID: 23340427	2013
Mass spectrometry imaging: linking molecule profiles to tissue spatial distribution. Expert review of proteomics\| PubMed ID: 23414355	2013
Dissection of the factor requirements for spliceosome disassembly and the elucidation of its dissociation products using a purified splicing system. Genes & development\| PubMed ID: 23431055	2013
Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion\| PubMed ID: 23438705	2013
An automated in-gel digestion/iTRAQ-labeling workflow for robust quantification of gel-separated proteins. Proteomics\| PubMed ID: 23456960	2013
Detecting endogenous SUMO targets in mammalian cells and tissues. Nature structural & molecular biology\| PubMed ID: 23503365	2013
β2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis. Blood\| PubMed ID: 23509157	2013
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta neuropathologica\| PubMed ID: 23604588	2013
Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Neuron\| PubMed ID: 23622064	2013
Mover is a homomeric phospho-protein present on synaptic vesicles. PloS one\| PubMed ID: 23723986	2013
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. The EMBO journal\| PubMed ID: 23727888	2013
Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma. Nature communications\| PubMed ID: 23828504	2013
Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions. Nucleic acids research\| PubMed ID: 23851565	2013
Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell reports\| PubMed ID: 23933260	2013
Increased proteome coverage by combining PAGE and peptide isoelectric focusing: comparative study of gel-based separation approaches. Proteomics\| PubMed ID: 23943586	2013
The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Molecular and cellular biology\| PubMed ID: 23979592	2013
Differential roles of postsynaptic density-93 isoforms in regulating synaptic transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24068818	2013
The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9. The Journal of biological chemistry\| PubMed ID: 24072711	2013
Immunostimulatory activity of murine keratinocyte-derived exosomes. Experimental dermatology\| PubMed ID: 24079734	2013
Structure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complex. Nature structural & molecular biology\| PubMed ID: 24121231	2013
Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry. Nucleic acids research\| PubMed ID: 24165877	2014
Cutting edge: feed-forward activation of phospholipase Cγ2 via C2 domain-mediated binding to SLP65. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24166973	2013
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure (London, England : 1993)\| PubMed ID: 24183573	2013
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. The EMBO journal\| PubMed ID: 24413018	2014
Mass spectrometry-based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spe... RNA (New York, N.Y.)\| PubMed ID: 24448447	2014
A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (crispr)-derived rnas (crrnas) in Haloferax vo... The Journal of biological chemistry\| PubMed ID: 24459147	2014
In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex. Nucleic acids research\| PubMed ID: 24500198	2014
The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation. Genes & development\| PubMed ID: 24696456	2014
Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D. Development (Cambridge, England)\| PubMed ID: 24718986	2014
Separation methodology to improve proteome coverage depth. Expert review of proteomics\| PubMed ID: 24834482	2014
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science (New York, N.Y.)\| PubMed ID: 24876496	2014
Biophysical and biochemical analysis of hnRNP K: arginine methylation, reversible aggregation and combinatorial binding to nucleic acids. Biological chemistry\| PubMed ID: 25003387	2014
Analyzing the protein assembly and dynamics of the human spliceosome with SILAC. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 25059615	2014
Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. RNA biology\| PubMed ID: 25117179	2014
Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins. Nature methods\| PubMed ID: 25173706	2014
Modulation of TCR responsiveness by the Grb2-family adaptor, Gads. Cellular signalling\| PubMed ID: 25452106	2015
RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular cell\| PubMed ID: 25457165	2014
Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. RNA biology\| PubMed ID: 25483036	2014
Dual tagging as an approach to isolate endogenous chromatin remodeling complexes from Saccharomyces cerevisiae. Biochimica et biophysica acta\| PubMed ID: 25486077	2015
Effects of mycophenolate mofetil on kidney function and phosphorylation status of renal proteins in Alport COL4A3-deficient mice. Proteome science\| PubMed ID: 25525413	2014
Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics\| PubMed ID: 25546807	2014
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature structural & molecular biology\| PubMed ID: 25599396	2015
FLT3-ITD and TLR9 employ Bruton's tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation. Blood\| PubMed ID: 25605370	2015