Vladimir Kefalov

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis

Affiliated withWashington University in St. Louis Washington University in St. Louis

Research Area

Neuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2015

Other Publications

Article	Year
Signaling States of Rhodopsin in Rod Disk Membranes Lacking Transducin Î²Î³-Complex. Investigative ophthalmology & visual science\| PubMed ID: 22266510	2012
Use of retinal analogues for the study of visual pigment function. Methods in enzymology\| PubMed ID: 11665574	2002
Role of visual pigment properties in rod and cone phototransduction. Nature\| PubMed ID: 14523449	2003
Breaking the covalent bond--a pigment property that contributes to desensitization in cones. Neuron\| PubMed ID: 15953417	2005
Molecular properties of rhodopsin and rod function. The Journal of biological chemistry\| PubMed ID: 17194706	2007
Signaling properties of a short-wave cone visual pigment and its role in phototransduction. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17881515	2007
Quantal noise from human red cone pigment. Nature neuroscience\| PubMed ID: 18425122	2008
Intra-retinal visual cycle required for rapid and complete cone dark adaptation. Nature neuroscience\| PubMed ID: 19182795	2009
Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19657028	2009
An alternative pathway mediates the mouse and human cone visual cycle. Current biology : CB\| PubMed ID: 19781940	2009
Functional interchangeability of rod and cone transducin alpha-subunits. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19815523	2009
Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability. Investigative ophthalmology & visual science\| PubMed ID: 19834036	2010
Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20164334	2010
Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20552424	2010
Age-related deterioration of rod vision in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20720130	2010
Membrane anchoring subunits specify selective regulation of RGS9Â·Gbeta5 GAP complex in photoreceptor neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20943919	2010
The cone-specific visual cycle. Progress in retinal and eye research\| PubMed ID: 21111842	2011
Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21430170	2011
Variation in rhodopsin kinase expression alters the dim flash response shut off and the light adaptation in rod photoreceptors. Investigative ophthalmology & visual science\| PubMed ID: 21474765	2011
The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21613504	2011
Role of guanylyl cyclase modulation in mouse cone phototransduction. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21632921	2011
G-protein betagamma-complex is crucial for efficient signal amplification in vision. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21632928	2011
Rod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approaches. The Journal of biological chemistry\| PubMed ID: 22074928	2012
Store-operated channels regulate intracellular calcium in mammalian rods. The Journal of physiology\| PubMed ID: 22674725	2012
Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization. The Journal of clinical investigation\| PubMed ID: 23221340	2013
Reprogramming of adult rod photoreceptors prevents retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23319618	2013
Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23637185	2013
Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23864662	2013
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis. Human molecular genetics\| PubMed ID: 24214395	2014
An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina. PloS one\| PubMed ID: 24349243	2013
R9AP overexpression alters phototransduction kinetics in iCre75 mice. Investigative ophthalmology & visual science\| PubMed ID: 24526444	2014
DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24812086	2014
FASEB Science Research Conference on Biology and Chemistry of Vision. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24891609	2014
Ex vivo ERG analysis of photoreceptors using an in vivo ERG system. Vision research\| PubMed ID: 24959652	2014
Chromophore supply rate-limits mammalian photoreceptor dark adaptation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25143602	2014
Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 25351983	2015
Human infrared vision is triggered by two-photon chromophore isomerization. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25453064	2014
CRALBP supports the mammalian retinal visual cycle and cone vision. The Journal of clinical investigation\| PubMed ID: 25607845	2015
Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling. PloS one\| PubMed ID: 25659125	2015
Regulation of Mammalian cone phototransduction by recoverin and rhodopsin kinase. The Journal of biological chemistry\| PubMed ID: 25673692	2015
Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations. Human molecular genetics\| PubMed ID: 25712131	2015
Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior. eLife\| PubMed ID: 25879270	2015