Department of Molecular Physiology and Biophysics
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Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11781323
Regulation of corepressor function by nuclear NADH.
Science (New York, N.Y.) Mar, 2002 | Pubmed ID: 11847309
The efficiency of two-photon photolysis of a "caged" fluorophore, o-1-(2-nitrophenyl)ethylpyranine, in relation to photodamage of synaptic terminals.
European biophysics journal : EBJ Feb, 2002 | Pubmed ID: 11908850
Pancreatic islet beta-cells transiently metabolize pyruvate.
The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12070148
A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin.
The Journal of biological chemistry Sep, 2002 | Pubmed ID: 12101177
Bioluminescence resonance energy transfer assays for protein-protein interactions in living cells.
Methods in molecular biology (Clifton, N.J.) , 2002 | Pubmed ID: 12136748
Control of glucose phosphorylation in L6 myotubes by compartmentalization, hexokinase, and glucose transport.
The Biochemical journal Feb, 2003 | Pubmed ID: 12410639
Phase sensitive demodulation in multiphoton microscopy.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada Jun, 2002 | Pubmed ID: 12533235
Bioluminescence resonance energy transfer: monitoring protein-protein interactions in living cells.
Methods in enzymology , 2003 | Pubmed ID: 12622156
Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase.
The Journal of cell biology Apr, 2003 | Pubmed ID: 12707306
Intrasequence GFP in class I MHC molecules, a rigid probe for fluorescence anisotropy measurements of the membrane environment.
Biophysical journal Jun, 2003 | Pubmed ID: 12770911
Chemically resolved imaging of biological cells and thin films by infrared scanning near-field optical microscopy.
Biophysical journal Oct, 2003 | Pubmed ID: 14507733
Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity.
The Biochemical journal Feb, 2004 | Pubmed ID: 14556651
Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines.
The Journal of biological chemistry Mar, 2004 | Pubmed ID: 14688272
Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye.
The Journal of cell biology Feb, 2004 | Pubmed ID: 14745001
An improved cyan fluorescent protein variant useful for FRET.
Nature biotechnology Apr, 2004 | Pubmed ID: 14990965
Quantitative NAD(P)H/flavoprotein autofluorescence imaging reveals metabolic mechanisms of pancreatic islet pyruvate response.
The Journal of biological chemistry Jul, 2004 | Pubmed ID: 15148320
Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH.
BMC endocrine disorders Jun, 2004 | Pubmed ID: 15193158
Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2004 | Pubmed ID: 15317941
High-contrast imaging of fluorescent protein FRET by fluorescence polarization microscopy.
Biophysical journal Feb, 2005 | Pubmed ID: 15613634
Substrate binding stoichiometry and kinetics of the norepinephrine transporter.
The Journal of biological chemistry May, 2005 | Pubmed ID: 15757904
Imaging Beta cell development in real-time using pancreatic explants from mice with green fluorescent protein-labeled pancreatic Beta cells.
In vitro cellular & developmental biology. Animal Jan-Feb, 2005 | Pubmed ID: 15926862
When two is better than one: elements of intravital microscopy.
PLoS biology Jun, 2005 | Pubmed ID: 15941359
Impaired glucagon secretory responses in mice lacking the type 1 sulfonylurea receptor.
American journal of physiology. Endocrinology and metabolism Oct, 2005 | Pubmed ID: 15941784
Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene.
Genesis (New York, N.Y. : 2000) Oct, 2005 | Pubmed ID: 16108006
Regulation of two insulin granule populations within the reserve pool by distinct calcium sources.
Journal of cell science Dec, 2005 | Pubmed ID: 16317050
Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice.
BMC endocrine disorders , 2005 | Pubmed ID: 16336655
Imaging pancreatic beta-cells in the intact pancreas.
American journal of physiology. Endocrinology and metabolism May, 2006 | Pubmed ID: 16368785
Critical role of gap junction coupled KATP channel activity for regulated insulin secretion.
PLoS biology Feb, 2006 | Pubmed ID: 16402858
Mechanisms of time-dependent potentiation of insulin release: involvement of nitric oxide synthase.
Diabetes Apr, 2006 | Pubmed ID: 16567525
Redox sensor CtBP mediates hypoxia-induced tumor cell migration.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2006 | Pubmed ID: 16740659
The coming of age of two-photon excitation imaging for intravital microscopy.
Advanced drug delivery reviews Sep, 2006 | Pubmed ID: 16971019
Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2007 | Pubmed ID: 17213307
Optimization of pairings and detection conditions for measurement of FRET between cyan and yellow fluorescent proteins.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada Jun, 2006 | Pubmed ID: 17481360
Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells.
Molecular biology of the cell Aug, 2007 | Pubmed ID: 17553928
Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction.
Diabetes Sep, 2007 | Pubmed ID: 17575085
X-ray structure of Cerulean GFP: a tryptophan-based chromophore useful for fluorescence lifetime imaging.
Biochemistry Sep, 2007 | Pubmed ID: 17685554
Leptin requires canonical migratory signaling pathways for induction of monocyte and macrophage chemotaxis.
American journal of physiology. Cell physiology Nov, 2007 | Pubmed ID: 17728393
Fluorescent protein FRET: the good, the bad and the ugly.
Trends in biochemical sciences Sep, 2007 | Pubmed ID: 17764955
FRET by fluorescence polarization microscopy.
Methods in cell biology , 2008 | Pubmed ID: 18155473
Two-photon excitation microscopy for the study of living cells and tissues.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] Nov, 2003 | Pubmed ID: 18228433
Optical lock-in detection of FRET using synthetic and genetically encoded optical switches.
Biophysical journal Jun, 2008 | Pubmed ID: 18281383
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
American journal of physiology. Endocrinology and metabolism Jun, 2008 | Pubmed ID: 18413672
Kinetics of a collagen-like polypeptide fragmentation after mid-IR free-electron laser ablation.
Biophysical journal Aug, 2008 | Pubmed ID: 18441025
Turning fluorescent proteins into energy-saving light bulbs.
Nature methods Jun, 2008 | Pubmed ID: 18511915
Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth.
Clinical & experimental metastasis , 2008 | Pubmed ID: 18787962
Gap junction coupling and calcium waves in the pancreatic islet.
Biophysical journal Dec, 2008 | Pubmed ID: 18805925
Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets.
The Journal of clinical investigation Nov, 2008 | Pubmed ID: 18846254
Subcutaneous transplantation of embryonic pancreas for correction of type 1 diabetes.
American journal of physiology. Endocrinology and metabolism Feb, 2009 | Pubmed ID: 19066321
Single-photon-counting detector for increased sensitivity in two-photon laser scanning microscopy.
Optics letters Dec, 2008 | Pubmed ID: 19079484
Chapter 4: Combining microfluidics and quantitative fluorescence microscopy to examine pancreatic islet molecular physiology.
Methods in cell biology , 2008 | Pubmed ID: 19118673
Rapid and inexpensive fabrication of polymeric microfluidic devices via toner transfer masking.
Lab on a chip Apr, 2009 | Pubmed ID: 19350094
Photoconversion in orange and red fluorescent proteins.
Nature methods May, 2009 | Pubmed ID: 19363494
Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.
The Biochemical journal Aug, 2009 | Pubmed ID: 19450229
Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass.
Journal of molecular and cellular cardiology Feb, 2010 | Pubmed ID: 19835880
Quantitative measurement of zinc secretion from pancreatic islets with high temporal resolution using droplet-based microfluidics.
Analytical chemistry Nov, 2009 | Pubmed ID: 19874061
Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo.
American journal of physiology. Endocrinology and metabolism Apr, 2010 | Pubmed ID: 20071562
Fluorescent protein tracking and detection: fluorescent protein structure and color variants.
Cold Spring Harbor protocols Dec, 2009 | Pubmed ID: 20150100
Fluorescent protein tracking and detection: applications using fluorescent proteins in living cells.
Cold Spring Harbor protocols Dec, 2009 | Pubmed ID: 20150101
Glucose suppression of glucagon secretion: metabolic and calcium responses from alpha-cells in intact mouse pancreatic islets.
The Journal of biological chemistry May, 2010 | Pubmed ID: 20231269
Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents.
Cancer research May, 2010 | Pubmed ID: 20430759
Gαo represses insulin secretion by reducing vesicular docking in pancreatic beta-cells.
Diabetes Oct, 2010 | Pubmed ID: 20622165
Rapid extravasation and establishment of breast cancer micrometastases in the liver microenvironment.
Molecular cancer research : MCR Oct, 2010 | Pubmed ID: 20724460
Fluorescence anisotropy of protein complexes in living cells.
Biophysical journal Sep, 2010 | Pubmed ID: 20858411
Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.
Nature medicine Dec, 2010 | Pubmed ID: 21076393
Fluorescent proteins at a glance.
Journal of cell science Jan, 2011 | Pubmed ID: 21187342
Quantification of factors influencing fluorescent protein expression using RMCE to generate an allelic series in the ROSA26 locus in mice.
Disease models & mechanisms Jul, 2011 | Pubmed ID: 21324933
Amphiregulin exosomes increase cancer cell invasion.
Current biology : CB May, 2011 | Pubmed ID: 21514161
Raman-shifted alexandrite laser for soft tissue ablation in the 6- to 7-µm wavelength range.
Biomedical optics express , 2011 | Pubmed ID: 21559139
Gap junctions and other mechanisms of cell-cell communication regulate basal insulin secretion in the pancreatic islet.
The Journal of physiology Nov, 2011 | Pubmed ID: 21930600
Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant.
Diabetes Feb, 2012 | Pubmed ID: 22315305
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