Kezhong Zhang

Genetic mechanisms of age regulation of protein C and blood coagulation.

New function for age-related stability element in conferring strict tissue-specific expression of human factor IX and protein C genes.

Limitation in use of heterologous reporter genes for gene promoter analysis. Silencer activity associated with the cloramphenicol acetyltransferase reporter gene.

Bone marrow stromal cells as a genetic platform for systemic delivery of therapeutic proteins in vivo: human factor IX model.

TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia.

Unfolding the toxicity of cholesterol.

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

Signaling the unfolded protein response from the endoplasmic reticulum.

The unfolded protein response--a stress signaling pathway of the endoplasmic reticulum.

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

ER stress signaling by regulated splicing: IRE1/HAC1/XBP1.

The unfolded protein response: a stress signaling pathway critical for health and disease.

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.

From endoplasmic-reticulum stress to the inflammatory response.

Identification and characterization of endoplasmic reticulum stress-induced apoptosis in vivo.

Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.

Association study of semaphorin 5A with risk of Parkinson's disease in a Chinese Han population.

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion.

An age-related homeostasis mechanism is essential for spontaneous amelioration of hemophilia B Leyden.

Regulation of apoptosis by the unfolded protein response.

ER stress controls iron metabolism through induction of hepcidin.

Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential.

Integration of ER stress, oxidative stress and the inflammatory response in health and disease.

The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease.

Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues.

Role of unfolded protein response in lipogenesis.

Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease.

Unfolded protein response in cancer: the physician's perspective.

Real-world exposure of airborne particulate matter triggers oxidative stress in an animal model.

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis.

Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice.

Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation.

Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model.

Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes.

ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.

Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells.

Endoplasmic reticulum stress and lipid metabolism.

Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model.

Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancer.

Aquaporin-assisted and ER-mediated mitochondrial fission: a hypothesis.

Exposure to fine airborne particulate matter induces macrophage infiltration, unfolded protein response, and lipid deposition in white adipose tissue.

The association between glycogen synthase kinase 3 beta (GSK3-β) polymorphisms and Parkinson's disease susceptibility: A meta-analysis.

Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis.

The serine-threonine kinase Inositol-requiring enzyme 1 α (IRE1α) promotes IL-4 production in T helper cells.

Diabetes mellitus is associated with hepatocellular carcinoma: a retrospective case-control study in hepatitis endemic area.

Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21.

Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health Study.

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis.

Correlations between plasma levels of amino acids and nonmotor symptoms in Parkinson's disease.

PM2.5 in Beijing - temporal pattern and its association with influenza.

Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells.

Endoplasmic reticulum stress response and transcriptional reprogramming.

Cross talk between ER stress, oxidative stress, and inflammation in health and disease.

Genome-wide identification, evolutionary, and expression analyses of histone H3 variants in plants.

SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model.

Reduced plasma taurine level in Parkinson's disease: association with motor severity and levodopa treatment.

Plasma antioxidant status and motor features in de novo Chinese Parkinson's disease patients.

Reduced plasma serotonin and 5-hydroxyindoleacetic acid levels in Parkinson's disease are associated with nonmotor symptoms.

Petroleum coke in the urban environment: a review of potential health effects.

COPII-Dependent ER Export: A Critical Component of Insulin Biogenesis and β-Cell ER Homeostasis.

Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models.

Lysine Acetylation of CREBH Regulates Fasting-Induced Hepatic Lipid Metabolism.

Regional homogeneity alterations differentiate between tremor dominant and postural instability gait difficulty subtypes of Parkinson's disease.

[Study on changes of plasma levels of oxidative stress biomarkers and its relation with cognition function in patients with parkinson's disease].

Microarray analysis of microRNA expression in bone marrow-derived progenitor cells from mice with type 2 diabetes.

Alterations of functional and structural connectivity of freezing of gait in Parkinson's disease.

A novel ER-microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression.

Nogo-B receptor deficiency increases liver X receptor alpha nuclear translocation and hepatic lipogenesis through an adenosine monophosphate-activated protein kinase alpha-dependent pathway.

CREBH Couples Circadian Clock With Hepatic Lipid Metabolism.

COX7AR is a Stress-inducible Mitochondrial COX Subunit that Promotes Breast Cancer Malignancy.

Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas.

Glucagon regulates hepatic lipid metabolism via cAMP and Insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosis.

Inositol Requiring Enzyme 1 Facilitates Diabetic Wound Healing through Modulating microRNAs.

Toll-like Receptor (TLR) Signaling Interacts with CREBH to Modulate High-density Lipoprotein (HDL) in Response to Bacterial Endotoxin.

Relationship between the plasma levels of neurodegenerative proteins and motor subtypes of Parkinson's disease.

ER Stress-induced Inflammasome Activation Contributes to Hepatic Inflammation and Steatosis.