Department of Pharmacology
Jochen Klein has not added Biography.
If you are Jochen Klein and would like to personalize this page please email our Author Liaison for assistance.
A homeostatic mechanism counteracting K(+) -evoked choline release in adult brain.
Journal of neurochemistry Mar, 2002 | Pubmed ID: 11948248
Dual modulation of striatal acetylcholine release by hyperforin, a constituent of St. John's wort.
The Journal of pharmacology and experimental therapeutics May, 2002 | Pubmed ID: 11961077
Breakdown of choline-containing phospholipids in rat brain during severe weight loss.
Neuroscience letters Jun, 2002 | Pubmed ID: 12052529
Stability of phospholipase D in primary astrocytes.
Biochemical and biophysical research communications Sep, 2002 | Pubmed ID: 12270129
NMDA-induced acetylcholine release in mouse striatum: role of NO synthase isoforms.
Journal of neurochemistry Sep, 2002 | Pubmed ID: 12354305
ADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosis.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12519790
Effects of septal grafts on acetylcholine release from rat hippocampus after 192 IgG-saporin lesion.
Neurochemical research Apr, 2003 | Pubmed ID: 12675132
Nitrergic modulation of hippocampal acetylcholine release is independent of endothelial NO synthase activity.
Neurochemical research Apr, 2003 | Pubmed ID: 12675148
Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis.
Resuscitation Aug, 2003 | Pubmed ID: 12909384
Mitogenic effects of phospholipase D and phosphatidic acid in transiently permeabilized astrocytes: effects of ethanol.
Journal of neurochemistry Oct, 2003 | Pubmed ID: 12969256
Stimulation of hippocampal acetylcholine release by hyperforin, a constituent of St. John's Wort.
Neuroscience letters Jul, 2004 | Pubmed ID: 15196674
Effects of norepinephrine and cardiotrophin-1 on phospholipase D activity and incorporation of myristic acid into phosphatidylcholine in rat heart.
Journal of pharmacological sciences Jul, 2004 | Pubmed ID: 15272209
Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients.
Neurobiology of aging Nov-Dec, 2004 | Pubmed ID: 15465626
Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes.
BMC pharmacology Feb, 2005 | Pubmed ID: 15694004
Microarray analysis and response of the lungs to inhaled insulin.
Diabetes technology & therapeutics Jun, 2005 | Pubmed ID: 15929684
NGP1-01, a lipophilic polycyclic cage amine, is neuroprotective in focal ischemia.
Neuroscience letters Jul 22-29, 2005 | Pubmed ID: 15936510
Functions and pathophysiological roles of phospholipase D in the brain.
Journal of neurochemistry Sep, 2005 | Pubmed ID: 16042758
NGP1-01 is a brain-permeable dual blocker of neuronal voltage- and ligand-operated calcium channels.
Neurochemical research Mar, 2006 | Pubmed ID: 16733815
NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort.
Journal of pharmacological sciences Sep, 2006 | Pubmed ID: 16936454
Effects of chloride flux modulators in an in vitro model of brain edema formation.
Brain research Nov, 2006 | Pubmed ID: 17014830
Role of GABAergic antagonism in the neuroprotective effects of bilobalide.
Brain research Jan, 2007 | Pubmed ID: 17134681
Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity.
Journal of neurochemistry Mar, 2007 | Pubmed ID: 17212694
Phenserine.
Expert opinion on investigational drugs Jul, 2007 | Pubmed ID: 17594192
Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice.
Neurochemistry international May, 2008 | Pubmed ID: 18023504
Neuroprotection in mice by NGP1-01 after transient focal brain ischemia.
Brain research Feb, 2008 | Pubmed ID: 18234166
Role of glycine receptors and glycine release for the neuroprotective activity of bilobalide.
Brain research Mar, 2008 | Pubmed ID: 18325484
Metabolism of boswellic acids in vitro and in vivo.
Drug metabolism and disposition: the biological fate of chemicals Jun, 2008 | Pubmed ID: 18356270
Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques , 2009 | Pubmed ID: 19470293
Neurotransmitters and energy metabolites in amyloid-bearing APP(SWE)xPSEN1dE9 Mouse Brain.
The Journal of pharmacology and experimental therapeutics Feb, 2010 | Pubmed ID: 19846589
Nicotine exacerbates brain edema during in vitro and in vivo focal ischemic conditions.
The Journal of pharmacology and experimental therapeutics Feb, 2010 | Pubmed ID: 19889792
Metabolic and transmitter changes in core and penumbra after middle cerebral artery occlusion in mice.
Brain research Feb, 2010 | Pubmed ID: 19961839
Quantitative determination of acetylcholine and choline in microdialysis samples by MALDI-TOF MS.
Analytical chemistry Feb, 2010 | Pubmed ID: 20058877
Acute depression of energy metabolism after microdialysis probe implantation is distinct from ischemia-induced changes in mouse brain.
Neurochemical research Jan, 2011 | Pubmed ID: 20878232
Lactate levels in the brain are elevated upon exposure to volatile anesthetics: a microdialysis study.
Neurochemistry international Dec, 2010 | Pubmed ID: 20933036
The ketogenic diet changes metabolite levels in hippocampal extracellular fluid.
Neurochemistry international Jan, 2011 | Pubmed ID: 21070829
Brain permeability of bilobalide as probed by microdialysis before and after middle cerebral artery occlusion in mice.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques , 2010 | Pubmed ID: 21486534
In vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery.
Expert opinion on drug discovery Feb, 2011 | Pubmed ID: 21532928
Neuroprotective effects of bilobalide are accompanied by a reduction of ischemia-induced glutamate release in vivo.
Brain research Nov, 2011 | Pubmed ID: 22032877
Ginkgo extract EGb761 confers neuroprotection by reduction of glutamate release in ischemic brain.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques , 2012 | Pubmed ID: 22365091
Uptake of lithium into rat brain after acute and chronic administration.
Neuroscience letters Jul, 2012 | Pubmed ID: 22659074
Near-complete adaptation of the PRiMA knockout to the lack of central acetylcholinesterase.
Journal of neurochemistry Sep, 2012 | Pubmed ID: 22747514
Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition.
Neuropharmacology Apr, 2013 | Pubmed ID: 23147415
Neuroprotective effects of lactate in brain ischemia: dependence on anesthetic drugs.
Neurochemistry international Feb, 2013 | Pubmed ID: 23298645
Blood gases and energy metabolites in mouse blood before and after cerebral ischemia: the effects of anesthetics.
Experimental biology and medicine (Maywood, N.J.) Jan, 2013 | Pubmed ID: 23479767
Neurodegeneration after transient brain ischemia in aged mice: beneficial effects of bilobalide.
Brain research Sep, 2013 | Pubmed ID: 23850645
Phospholipase D is a target for inhibition of astroglial proliferation by ethanol.
Neuropharmacology Apr, 2014 | Pubmed ID: 24262632
Choline acetyltransferase and organic cation transporters are responsible for synthesis and propionate-induced release of acetylcholine in colon epithelium.
European journal of pharmacology Jun, 2014 | Pubmed ID: 24698650
Impaired brain development and reduced cognitive function in phospholipase D-deficient mice.
Neuroscience letters Jun, 2014 | Pubmed ID: 24813107
Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2014 | Pubmed ID: 24843119
Dynamics of hippocampal acetylcholine release during lithium-pilocarpine-induced status epilepticus in rats.
Journal of neurochemistry Oct, 2014 | Pubmed ID: 24909269
Self-built microdialysis probes with improved recoveries of ATP and neuropeptides.
Journal of neuroscience methods Nov, 2014 | Pubmed ID: 25172804
Detection and Site Localization of Phosphorylcholine-Modified Peptides by NanoLC-ESI-MS/MS Using Precursor Ion Scanning and Multiple Reaction Monitoring Experiments.
Journal of the American Society for Mass Spectrometry Mar, 2015 | Pubmed ID: 25487775
Role of phospholipases D1 and 2 in astroglial proliferation: effects of specific inhibitors and genetic deletion.
European journal of pharmacology May, 2015 | Pubmed ID: 25967349
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved