Institute for Cell Engineering Neuroregeneration and Stem Cell Programs,
Departments of Neurology,
Neuroscience,
and Oncology,
Departments of Neurology, Neuroscience, and Oncology
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The role of notch in promoting glial and neural stem cell fates.
Annual review of neuroscience , 2002 | Pubmed ID: 12052917
Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.
Development (Cambridge, England) Nov, 2002 | Pubmed ID: 12397105
Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning.
Development (Cambridge, England) Oct, 2003 | Pubmed ID: 12930780
Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2004 | Pubmed ID: 15509736
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.
Nature immunology Mar, 2005 | Pubmed ID: 15665828
Radial 'glial' progenitors: neurogenesis and signaling.
Current opinion in neurobiology Feb, 2005 | Pubmed ID: 15721741
Notch signaling in the mammalian central nervous system: insights from mouse mutants.
Nature neuroscience Jun, 2005 | Pubmed ID: 15917835
Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon.
Developmental neuroscience , 2006 | Pubmed ID: 16508304
Chalk one up for 'nature' during neocortical neurogenesis.
Nature neuroscience Jun, 2006 | Pubmed ID: 16732198
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Nature Feb, 2007 | Pubmed ID: 17259973
Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.
Nature Sep, 2007 | Pubmed ID: 17721509
Fibroblast growth factor receptor 2 plays an essential role in telencephalic progenitors.
Developmental neuroscience , 2008 | Pubmed ID: 18073459
Imaging hematopoietic precursor division in real time.
Cell stem cell Nov, 2007 | Pubmed ID: 18345353
Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment.
Cell stem cell May, 2008 | Pubmed ID: 18462696
Regulation of neural progenitor cell development in the nervous system.
Journal of neurochemistry Sep, 2008 | Pubmed ID: 18819190
Strange bedfellows: Reelin and Notch signaling interact to regulate cell migration in the developing neocortex.
Neuron Oct, 2008 | Pubmed ID: 18957210
PML: a tumor suppressor essential for neocortical development.
Nature neuroscience Feb, 2009 | Pubmed ID: 19172164
Preview. Meninges Play a RAdical Role in Embryonic Neural Stem Cell Regulation.
Cell stem cell Nov, 2009 | Pubmed ID: 19896433
Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop.
Journal of neurosurgery. Spine Feb, 2010 | Pubmed ID: 20121344
The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
Nature neuroscience May, 2010 | Pubmed ID: 20364144
Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injury.
Stroke; a journal of cerebral circulation Oct, 2010 | Pubmed ID: 20876509
A dynamic notch injury response activates epicardium and contributes to fibrosis repair.
Circulation research Jan, 2011 | Pubmed ID: 21106942
Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells.
Biochemical and biophysical research communications Jan, 2011 | Pubmed ID: 21108929
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2010 | Pubmed ID: 21169257
Notch3 activation promotes invasive glioma formation in a tissue site-specific manner.
Cancer research Feb, 2011 | Pubmed ID: 21245095
Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.
Neuron Feb, 2011 | Pubmed ID: 21315255
Notch in the vertebrate nervous system: an old dog with new tricks.
Neuron Mar, 2011 | Pubmed ID: 21382546
Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism.
Genes & development Jul, 2011 | Pubmed ID: 21724832
Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.
Science (New York, N.Y.) Dec, 2011 | Pubmed ID: 22116031
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