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Institute for Cell Engineering Neuroregeneration and Stem Cell Programs,
Departments of Neurology,
Neuroscience,
and Oncology,
Departments of Neurology, Neuroscience, and Oncology
Nicholas Gaiano has not added Biography.
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The role of notch in promoting glial and neural stem cell fates.
Annual review of neuroscience , 2002 | Pubmed ID: 12052917
Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.
Development (Cambridge, England) Nov, 2002 | Pubmed ID: 12397105
Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning.
Development (Cambridge, England) Oct, 2003 | Pubmed ID: 12930780
Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2004 | Pubmed ID: 15509736
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.
Nature immunology Mar, 2005 | Pubmed ID: 15665828
Radial 'glial' progenitors: neurogenesis and signaling.
Current opinion in neurobiology Feb, 2005 | Pubmed ID: 15721741
Notch signaling in the mammalian central nervous system: insights from mouse mutants.
Nature neuroscience Jun, 2005 | Pubmed ID: 15917835
Notch3 signaling promotes radial glial/progenitor character in the mammalian telencephalon.
Developmental neuroscience , 2006 | Pubmed ID: 16508304
Chalk one up for 'nature' during neocortical neurogenesis.
Nature neuroscience Jun, 2006 | Pubmed ID: 16732198
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Nature Feb, 2007 | Pubmed ID: 17259973
Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.
Nature Sep, 2007 | Pubmed ID: 17721509
Fibroblast growth factor receptor 2 plays an essential role in telencephalic progenitors.
Developmental neuroscience , 2008 | Pubmed ID: 18073459
Imaging hematopoietic precursor division in real time.
Cell stem cell Nov, 2007 | Pubmed ID: 18345353
Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment.
Cell stem cell May, 2008 | Pubmed ID: 18462696
Regulation of neural progenitor cell development in the nervous system.
Journal of neurochemistry Sep, 2008 | Pubmed ID: 18819190
Strange bedfellows: Reelin and Notch signaling interact to regulate cell migration in the developing neocortex.
Neuron Oct, 2008 | Pubmed ID: 18957210
PML: a tumor suppressor essential for neocortical development.
Nature neuroscience Feb, 2009 | Pubmed ID: 19172164
Preview. Meninges Play a RAdical Role in Embryonic Neural Stem Cell Regulation.
Cell stem cell Nov, 2009 | Pubmed ID: 19896433
Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop.
Journal of neurosurgery. Spine Feb, 2010 | Pubmed ID: 20121344
The exon junction complex component Magoh controls brain size by regulating neural stem cell division.
Nature neuroscience May, 2010 | Pubmed ID: 20364144
Neonatal stroke in mice causes long-term changes in neuronal Notch-2 expression that may contribute to prolonged injury.
Stroke; a journal of cerebral circulation Oct, 2010 | Pubmed ID: 20876509
A dynamic notch injury response activates epicardium and contributes to fibrosis repair.
Circulation research Jan, 2011 | Pubmed ID: 21106942
Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells.
Biochemical and biophysical research communications Jan, 2011 | Pubmed ID: 21108929
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2010 | Pubmed ID: 21169257
Notch3 activation promotes invasive glioma formation in a tissue site-specific manner.
Cancer research Feb, 2011 | Pubmed ID: 21245095
Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.
Neuron Feb, 2011 | Pubmed ID: 21315255
Notch in the vertebrate nervous system: an old dog with new tricks.
Neuron Mar, 2011 | Pubmed ID: 21382546
Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism.
Genes & development Jul, 2011 | Pubmed ID: 21724832
Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.
Science (New York, N.Y.) Dec, 2011 | Pubmed ID: 22116031
Johns Hopkins University School of Medicine
Tarran J. Pierfelice1,
Nicholas Gaiano1,2
1Institute for Cell Engineering Neuroregeneration and Stem Cell Programs, Johns Hopkins University School of Medicine,
2Departments of Neurology, Neuroscience, and Oncology, Johns Hopkins University School of Medicine
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