Department of Microbiology and Immunology
Research in our laboratory focuses on the molecular biology and in the evasion of the innate immune response by negative strand RNA viruses.
Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses.
Journal of virology Feb, 2011 | Pubmed ID: 21123370
The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response.
Journal of virology Dec, 2011 | Pubmed ID: 21976642
Host-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 protein.
PloS one , 2011 | Pubmed ID: 22174864
The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: a new class of adjuvant?
Journal of immunology (Baltimore, Md. : 1950) Dec, 2014 | Pubmed ID: 25392529
Replication-competent influenza A viruses expressing a red fluorescent protein.
Virology Feb, 2015 | Pubmed ID: 25553516
Competitive detection of influenza neutralizing antibodies using a novel bivalent fluorescence-based microneutralization assay (BiFMA).
Vaccine Jul, 2015 | Pubmed ID: 26044496
Development and applications of single-cycle infectious influenza A virus (sciIAV).
Virus research May, 2016 | Pubmed ID: 26220478
Replication-competent fluorescent-expressing influenza B virus.
Virus research Feb, 2016 | Pubmed ID: 26590325
Replication-Competent Influenza A and B Viruses Expressing a Fluorescent Dynamic Timer Protein for In Vitro and In Vivo Studies.
PloS one , 2016 | Pubmed ID: 26809059
Reverse Genetics Approaches to Control Arenavirus.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 27076139
Replication-Competent Influenza A Viruses Expressing Reporter Genes.
Viruses 06, 2016 | Pubmed ID: 27347991
Reverse Genetics Approaches for the Development of Influenza Vaccines.
International journal of molecular sciences Dec, 2016 | Pubmed ID: 28025504
A live-attenuated influenza vaccine for H3N2 canine influenza virus.
Virology 04, 2017 | Pubmed ID: 28167384
Development of Recombinant Arenavirus-Based Vaccines.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28374247
Lassa Virus Reverse Genetics.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28508222
Reverse Genetics of Influenza B Viruses.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28508223
Plasmid-Based Reverse Genetics of Influenza A Virus.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28508225
Interplay of PA-X and NS1 Proteins in Replication and Pathogenesis of a Temperature-Sensitive 2009 Pandemic H1N1 Influenza A Virus.
Journal of virology 09, 2017 | Pubmed ID: 28637750
A bivalent live-attenuated influenza vaccine for the control and prevention of H3N8 and H3N2 canine influenza viruses.
Vaccine 08, 2017 | Pubmed ID: 28709557
The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression.
Journal of virology 11, 2017 | Pubmed ID: 28835506
Development of a novel equine influenza virus live-attenuated vaccine.
Virology 03, 2018 | Pubmed ID: 29331866
Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage.
American journal of physiology. Lung cellular and molecular physiology 03, 2018 | Pubmed ID: 29351447
A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody.
Scientific reports Mar, 2018 | Pubmed ID: 29531320
An Alanine-to-Valine Substitution in the Residue 175 of Zika Virus NS2A Protein Affects Viral RNA Synthesis and Attenuates the Virus In Vivo.
Viruses 10, 2018 | Pubmed ID: 30301244
Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine.
Viruses 10, 2018 | Pubmed ID: 30326610
Reverse Genetic Approaches for the Generation of Recombinant Zika Virus.
Viruses 10, 2018 | Pubmed ID: 30384426
Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins.
Viruses 12, 2018 | Pubmed ID: 30545063
Novel Approaches for The Development of Live Attenuated Influenza Vaccines.
Viruses 02, 2019 | Pubmed ID: 30813325
Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells.
mBio 03, 2019 | Pubmed ID: 30862743
A Novel Fluorescent and Bioluminescent Bireporter Influenza A Virus To Evaluate Viral Infections.
Journal of virology May, 2019 | Pubmed ID: 30867298
New Advances on Zika Virus Research.
Viruses 03, 2019 | Pubmed ID: 30875715
1Department of Microbiology, Icahn School of Medicine at Mount Sinai,
2Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai,
3Department of Medicine, Icahn School of Medicine at Mount Sinai,
4Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester
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