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Influenza A Virus Studies in a Mouse Model of Infection

DOI :

10.3791/55898-v

September 7th, 2017

September 7th, 2017

26,961 Views

1Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry

Influenza A viruses (IAVs) are important human respiratory pathogens. To understand the pathogenicity of IAVs and to perform preclinical testing of novel vaccine approaches, animal models mimicking human physiology are required. Here, we describe techniques to evaluate IAV pathogenesis, humoral responses and vaccine efficacy using a mouse model of infection.

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Influenza A Virus

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