Georgia Pennarossa

Laboratory of Biomedical Embryology,
Unistem,
Centre for Stem Cell Research,
Department of Health,
Animal Science and Food Safety and Center for Stem Cell Research,
Laboratory of Biomedical Embryology, Unistem, Centre for Stem Cell Research,
Laboratory of Biomedical Embryology, Department of Health, Animal Science and Food Safety and Center for Stem Cell Research

Università degli Studi di Milano

BIOGRAPHY

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PUBLICATIONS

Parthenogenesis as an approach to pluripotency: advantages and limitations involved.

Stem cell reviews Sep, 2008 | Pubmed ID: 18548354

Cell lines derived from human parthenogenetic embryos can display aberrant centriole distribution and altered expression levels of mitotic spindle check-point transcripts.

Stem cell reviews Dec, 2009 | Pubmed ID: 20058199

Culture conditions and signalling networks promoting the establishment of cell lines from parthenogenetic and biparental pig embryos.

Stem cell reviews Sep, 2010 | Pubmed ID: 20407852

Parthenogenetic cell lines: an unstable equilibrium between pluripotency and malignant transformation.

Current pharmaceutical biotechnology Feb, 2011 | Pubmed ID: 21044006

Centrosome amplification and chromosomal instability in human and animal parthenogenetic cell lines.

Stem cell reviews Dec, 2012 | Pubmed ID: 22661117

Characterization of the constitutive pig ovary heat shock chaperone machinery and its response to acute thermal stress or to seasonal variations.

Biology of reproduction Nov, 2012 | Pubmed ID: 23018186

Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells.

Proceedings of the National Academy of Sciences of the United States of America May, 2013 | Pubmed ID: 23696663

Direct comparative analysis of conventional and directional freezing for the cryopreservation of whole ovaries.

Fertility and sterility Oct, 2013 | Pubmed ID: 23830108

Morphological and molecular changes of human granulosa cells exposed to 5-azacytidine and addressed toward muscular differentiation.

Stem cell reviews Oct, 2014 | Pubmed ID: 24858410

Intercellular bridges are essential for human parthenogenetic cell survival.

Mechanisms of development May, 2015 | Pubmed ID: 25700933

Extended ex vivo culture of fresh and cryopreserved whole sheep ovaries.

Reproduction, fertility, and development Jun, 2015 | Pubmed ID: 26072996

Erase and Rewind: Epigenetic Conversion of Cell Fate.

Stem cell reviews Nov, 2015 | Pubmed ID: 26589198

5-azacytidine affects TET2 and histone transcription and reshapes morphology of human skin fibroblasts.

Scientific reports 11, 2016 | Pubmed ID: 27841324

Epigenetic Erasing and Pancreatic Differentiation of Dermal Fibroblasts into Insulin-Producing Cells are Boosted by the Use of Low-Stiffness Substrate.

Stem cell reviews and reports , | Pubmed ID: 29285667

Safety and Efficacy of Epigenetically Converted Human Fibroblasts Into Insulin-Secreting Cells: A Preclinical Study.

Advances in experimental medicine and biology , 2018 | Pubmed ID: 29500792

Use of a PTFE Micro-Bioreactor to Promote 3D Cell Rearrangement and Maintain High Plasticity in Epigenetically Erased Fibroblasts.

Stem cell reviews and reports 02, 2019 | Pubmed ID: 30397853

Rho Signaling-Directed YAP/TAZ Regulation Encourages 3D Spheroid Colony Formation and Boosts Plasticity of Parthenogenetic Stem Cells.

Advances in experimental medicine and biology , 2020 | Pubmed ID: 31376140

Whole-ovary decellularization generates an effective 3D bioscaffold for ovarian bioengineering.

Journal of assisted reproduction and genetics Jun, 2020 | Pubmed ID: 32361917

INSTITUTIONS

Università degli Studi di Milano

JOVE ARTICLES

Epigenetic Conversion as a Safe and Simple Method to Obtain Insulin-secreting Cells from Adult Skin Fibroblasts

Tiziana A.L. Brevini¹,

Georgia Pennarossa¹,

Sara Maffei¹,

Alessandro Zenobi¹,

Fulvio Gandolfi¹

¹Laboratory of Biomedical Embryology, Unistem, Centre for Stem Cell Research, Università degli Studi di Milano

Developmental Biology

A Two-Step Strategy that Combines Epigenetic Modification and Biomechanical Cues to Generate Mammalian Pluripotent Cells

Georgia Pennarossa¹,

Sergio Ledda²,

Sharon Arcuri¹,

Fulvio Gandolfi³,

Tiziana A. L. Brevini¹

¹Laboratory of Biomedical Embryology, Department of Health, Animal Science and Food Safety and Center for Stem Cell Research, Università degli Studi di Milano,

²Department of Veterinary Medicine, University of Sassari,

³Department of Agricultural and Environmental Sciences - Production, Landscape, Agroenergy and Center for Stem Cell Research, Università degli Studi di Milano

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