Department of Cancer Biology
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c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis.
The EMBO journal Jul, 2002 | Pubmed ID: 12110583
The FLIP side of cancer cell death.
Cancer biology & therapy Jul-Aug, 2002 | Pubmed ID: 12432256
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12525502
DEDD and DEDD2 associate with caspase-8/10 and signal cell death.
Oncogene Jan, 2003 | Pubmed ID: 12527898
Activation of procaspases by FK506 binding protein-mediated oligomerization.
Science's STKE : signal transduction knowledge environment Jan, 2003 | Pubmed ID: 12554853
Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases.
The Journal of biological chemistry May, 2003 | Pubmed ID: 12637514
Interdimer processing mechanism of procaspase-8 activation.
The EMBO journal Aug, 2003 | Pubmed ID: 12912912
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein.
The Journal of biological chemistry May, 2004 | Pubmed ID: 14990586
Interdimer processing and linearity of procaspase-3 activation. A unifying mechanism for the activation of initiator and effector caspases.
The Journal of biological chemistry Mar, 2005 | Pubmed ID: 15664982
The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62.
FEBS letters May, 2005 | Pubmed ID: 15878163
Association of caspase-2 with the promyelocytic leukemia protein nuclear bodies.
Cancer biology & therapy Jun, 2005 | Pubmed ID: 15917662
Lymphocyte life and death: the caspase-8 connection.
Cancer biology & therapy Jul, 2005 | Pubmed ID: 16082181
cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas.
The Journal of clinical investigation Jan, 2006 | Pubmed ID: 16395405
CIAP2 inhibits anigen receptor signaling by targeting Bcl10 for degredation.
Cell cycle (Georgetown, Tex.) Jul, 2006 | Pubmed ID: 16775419
A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma.
Genes, chromosomes & cancer Sep, 2006 | Pubmed ID: 16804917
Critical role for Daxx in regulating Mdm2.
Nature cell biology Aug, 2006 | Pubmed ID: 16845383
Lys63-linked polyubiquitin chains: linking more than just ubiquitin.
Cancer biology & therapy Oct, 2006 | Pubmed ID: 16969079
TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis.
Cell May, 2008 | Pubmed ID: 18455983
Ubiquitination mediated by inhibitor of apoptosis proteins.
Methods in enzymology , 2008 | Pubmed ID: 18603125
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation.
Molecular cell Aug, 2008 | Pubmed ID: 18691973
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
Nature immunology Dec, 2008 | Pubmed ID: 18997794
Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF through a mitochondrial ROS pathway in vitro.
Investigative ophthalmology & visual science Jan, 2010 | Pubmed ID: 19696171
Distinct MHC gene expression patterns during progression of melanoma.
Genes, chromosomes & cancer Feb, 2010 | Pubmed ID: 19862823
Daxx is reciprocally regulated by Mdm2 and Hausp.
Biochemical and biophysical research communications Mar, 2010 | Pubmed ID: 20153724
tRNA binds to cytochrome c and inhibits caspase activation.
Molecular cell Mar, 2010 | Pubmed ID: 20227371
tRNA and cytochrome c in cell death and beyond.
Cell cycle (Georgetown, Tex.) Aug, 2010 | Pubmed ID: 20676046
Apoptotic regulation and tRNA.
Protein & cell Sep, 2010 | Pubmed ID: 21113408
[Study on effect of total saponins from Semen Nigellae on inflammatory mediators and ERK/MAPK pathway in stimulated macrophage].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica Oct, 2010 | Pubmed ID: 21174772
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase.
Nature cell biology Mar, 2011 | Pubmed ID: 21336310
Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21768358
The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2.
The Journal of biological chemistry Oct, 2011 | Pubmed ID: 21849505
Effects of a novel peptide derived from human thrombomodulin on endotoxin-induced uveitis in vitro and in vivo.
FEBS letters Nov, 2011 | Pubmed ID: 22001200
[Mitochondrial dysfunction induced by excessive ROS/RNS-metabolic cardiovascular disease and traditional Chinese medicines intervention].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica Sep, 2011 | Pubmed ID: 22121816
Chemical composition of volatile oil from Artemisia ordosica and its allelopathic effects on desert soil microalgae, Palmellococcus miniatus.
Plant physiology and biochemistry : PPB / Société française de physiologie végétale Feb, 2012 | Pubmed ID: 22153252
Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2011 | Pubmed ID: 22158899
A novel peptide derived from human pancreatitis-associated protein inhibits inflammation in vivo and in vitro and blocks NF-kappa B signaling pathway.
PloS one , 2011 | Pubmed ID: 22195011
A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma.
Cancer discovery Feb, 2012 | Pubmed ID: 22585859
Dissecting the complex regulation of Mad4 in glioblastoma multiforme cells.
Cancer biology & therapy Nov, 2012 | Pubmed ID: 22895069
Gd complexes of diethylenetriaminepentaacetic acid conjugates of low-molecular-weight chitosan oligosaccharide as a new liver-specific MRI contrast agent.
Magnetic resonance imaging May, 2013 | Pubmed ID: 23102519
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence.
Nature Jan, 2013 | Pubmed ID: 23334421
Regulation of cell death by transfer RNA.
Antioxidants & redox signaling Aug, 2013 | Pubmed ID: 23350625
Effects of a thrombomodulin-derived peptide on monocyte adhesion and intercellular adhesion molecule-1 expression in lipopolysaccharide-induced endothelial cells.
Molecular vision , 2013 | Pubmed ID: 23401649
Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
PloS one , 2013 | Pubmed ID: 23405218
Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity.
The Journal of biological chemistry Jun, 2013 | Pubmed ID: 23671280
TAp73 enhances the pentose phosphate pathway and supports cell proliferation.
Nature cell biology Aug, 2013 | Pubmed ID: 23811687
A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation.
Cell cycle (Georgetown, Tex.) Dec, 2013 | Pubmed ID: 24270845
p53 and regulation of tumor metabolism.
Journal of carcinogenesis , 2013 | Pubmed ID: 24379735
Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells.
Cell cycle (Georgetown, Tex.) , 2014 | Pubmed ID: 24552816
MicroRNA-93 inhibits inflammatory cytokine production in LPS-stimulated murine macrophages by targeting IRAK4.
FEBS letters May, 2014 | Pubmed ID: 24642374
Stabilized human TRIM5α protects human T cells from HIV-1 infection.
Molecular therapy : the journal of the American Society of Gene Therapy Jun, 2014 | Pubmed ID: 24662946
A cellular system that degrades misfolded proteins and protects against neurodegeneration.
Molecular cell Jul, 2014 | Pubmed ID: 24882209
Olive leaf extract inhibits lead poisoning-induced brain injury.
Neural regeneration research Aug, 2013 | Pubmed ID: 25206510
Peptidyl-prolyl isomerization targets rice Aux/IAAs for proteasomal degradation during auxin signalling.
Nature communications , 2015 | Pubmed ID: 26096057
PAPep, a small peptide derived from human pancreatitis-associated protein, attenuates corneal inflammation in vivo and in vitro through the IKKα/β/IκBα/NF-κB signaling pathway.
Pharmacological research Dec, 2015 | Pubmed ID: 26388492
Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction.
The Journal of biological chemistry May, 2016 | Pubmed ID: 26961879
Isolation and evaluation of endophytic Streptomyces endus OsiSh-2 with potential application for biocontrol of rice blast disease.
Journal of the science of food and agriculture Jun, 2016 | Pubmed ID: 27293085
Two SNAP-25 genetic variants in the binding site of multiple microRNAs and susceptibility of ADHD: A meta-analysis.
Journal of psychiatric research Jun, 2016 | Pubmed ID: 27380186
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