William Matsui

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine

Affiliated withJohns Hopkins University School of Medicine

Research Area

Biology

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2010

Other Publications

Article	Year
The role of growth factors in the activity of pharmacological differentiation agents. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research\| PubMed ID: 12114217	2002
Anti-tumour activity of interferon-alpha in multiple myeloma: role of interleukin 6 and tumor cell differentiation. British journal of haematology\| PubMed ID: 12694246	2003
Characterization of clonogenic multiple myeloma cells. Blood\| PubMed ID: 14630803	2004
Cancer stem cells: are we missing the target? Journal of the National Cancer Institute\| PubMed ID: 15100335	2004
Enhanced cytotoxicity of rituximab following genetic and biochemical disruption of glycosylphosphatidylinositol anchored proteins. Leukemia & lymphoma\| PubMed ID: 15160958	2004
Association of Foxp3 regulatory gene expression with graft-versus-host disease. Blood\| PubMed ID: 15172973	2004
Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors. Cancer research\| PubMed ID: 15753403	2005
Requirement for myeloid growth factors in the differentiation of acute promyelocytic leukaemia. British journal of haematology\| PubMed ID: 15755292	2005
Do neoplastic stem cells underlie the pathogenesis of cutaneous lymphomas? Archives of dermatology\| PubMed ID: 15897396	2005
Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors. British journal of haematology\| PubMed ID: 16042686	2005
The paradox of response and survival in cancer therapeutics. Blood\| PubMed ID: 16150939	2006
Graft-versus-host reactions and the effectiveness of donor lymphocyte infusions. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 16545725	2006
Strategies to eliminate cancer stem cells: clinical implications. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 16644203	2006
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer research\| PubMed ID: 16885340	2006
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer research\| PubMed ID: 17332349	2007
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17360475	2007
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem cells (Dayton, Ohio)\| PubMed ID: 17628016	2007
Induction of autologous graft-versus-host disease: results of a randomized prospective clinical trial in patients with poor risk lymphoma. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 17889355	2007
The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity. Blood\| PubMed ID: 17942756	2008
Therapeutic implications of leukemic stem cell pathways. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18006753	2007
Cancer Stem Cells: From Bench to Bedside. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 18167509	2007
Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer research\| PubMed ID: 18172311	2008
Myeloablative allogeneic bone marrow transplant using T cell depleted allografts followed by post-transplant GM-CSF in high-risk myelodysplastic syndromes. Leukemia research\| PubMed ID: 18261793	2008
HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 18489989	2008
Multiple myeloma cancer stem cells. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 18539970	2008
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer. Molecular cancer therapeutics\| PubMed ID: 18790753	2008
Cancer stem cells in multiple myeloma. Cancer letters\| PubMed ID: 18809245	2009
Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH. Experimental hematology\| PubMed ID: 19013003	2009
A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development. Molecular cancer therapeutics\| PubMed ID: 19174553	2009
Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer. Cancer research\| PubMed ID: 19176379	2009
Circulating clonotypic B cells in classic Hodgkin lymphoma. Blood\| PubMed ID: 19188663	2009
GLI1 是直接的 EWS FLI1 基因转录目标。 The Journal of biological chemistry\| PubMed ID: 19189974	2009
Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19258443	2009
Higher serum folate levels are associated with a lower risk of atopy and wheeze. The Journal of allergy and clinical immunology\| PubMed ID: 19409604	2009
Smoothening the controversial role of hedgehog in hematopoiesis. Cell stem cell\| PubMed ID: 19497273	2009
DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation. Stem cells (Dayton, Ohio)\| PubMed ID: 19544453	2009
Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma. Stem cells (Dayton, Ohio)\| PubMed ID: 19544456	2009
Cancer stem cells: controversies in multiple myeloma. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 19760278	2009
Nonmyeloablative HLA-haploidentical bone marrow transplantation with high-dose posttransplantation cyclophosphamide: effect of HLA disparity on outcome. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 19925877	2010
Urothelial carcinoma: stem cells on the edge. Cancer metastasis reviews\| PubMed ID: 20012172	2009
High-dose cyclophosphamide for severe aplastic anemia: long-term follow-up. Blood\| PubMed ID: 20018919	2010
Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors. Blood\| PubMed ID: 20107231	2010
High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease. Blood\| PubMed ID: 20124511	2010
Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma. Journal of the National Cancer Institute\| PubMed ID: 20164446	2010
Multiple myeloma: a paradigm for translation of the cancer stem cell hypothesis. Anti-cancer agents in medicinal chemistry\| PubMed ID: 20184542	2010
Targeting Hedgehog--a cancer stem cell pathway. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 20530699	2010
Mantle cell lymphoma activation enhances bortezomib sensitivity. Blood\| PubMed ID: 20570863	2010
Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF. Leukemia research\| PubMed ID: 20598742	2011
A combination of DR5 agonistic monoclonal antibody with gemcitabine targets pancreatic cancer stem cells and results in long-term disease control in human pancreatic cancer model. Molecular cancer therapeutics\| PubMed ID: 20660600	2010
Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres. The American journal of pathology\| PubMed ID: 20671264	2010
Tumor-initiating cells are rare in many human tumors. Cell stem cell\| PubMed ID: 20804964	2010
Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms. PloS one\| PubMed ID: 20824134	2010
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer research\| PubMed ID: 20841480	2010
Characterization of chronic myeloid leukemia stem cells. American journal of hematology\| PubMed ID: 21132730	2011
Hedgehog signaling in hematopoiesis. Critical reviews in eukaryotic gene expression\| PubMed ID: 21133842	2010
Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926. PloS one\| PubMed ID: 21203400	2010
Concise review: Emerging concepts in clinical targeting of cancer stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 21509907	2011
Development and maintenance of cancer stem cells under chronic inflammation. Journal of Nihon Medical School = Nihon Ika Daigaku zasshi\| PubMed ID: 21720087	2011
High-dose cyclophosphamide and rituximab without stem cell transplant: a feasibility study for low grade B-cell, transformed and mantle cell lymphomas. Leukemia & lymphoma\| PubMed ID: 21756035	2011
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models. Cancer biology & therapy\| PubMed ID: 21768779	2011
The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels. Blood\| PubMed ID: 22039262	2011
Perspective: A model disease. Nature\| PubMed ID: 22169808	2011
Autologous stem cell transplantation and multiple myeloma cancer stem cells. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 22226109	2012
Cancer stem cells: relevance to clinical transplantation. Current opinion in oncology\| PubMed ID: 22314617	2012
Biological and clinical relevance of stem cells in pancreatic adenocarcinoma. Journal of gastroenterology and hepatology\| PubMed ID: 22320910	2012