Sabrina Ehnert

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice.

Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.

The possible use of stem cells in regenerative medicine: dream or reality?

Neohepatocytes from alcoholics and controls express hepatocyte markers and display reduced fibrogenic TGF-ß/Smad3 signaling: advantage for cell transplantation?

TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I.

In vitro differentiated adult human liver progenitor cells display mature hepatic metabolic functions: a potential tool for in vitro pharmacotoxicological testing.

TGF-β1 as possible link between loss of bone mineral density and chronic inflammation.

Cell therapeutic options in liver diseases: cell types, medical devices and regulatory issues.

Hepatotropic growth factors protect hepatocytes during inflammation by upregulation of antioxidative systems.

Comparative analysis of phase I and II enzyme activities in 5 hepatic cell lines identifies Huh-7 and HCC-T cells with the highest potential to study drug metabolism.

L-carnosine inhibits high-glucose-mediated matrix accumulation in human mesangial cells by interfering with TGF-β production and signalling.

Breast milk contains relevant neurotrophic factors and cytokines for enteric nervous system development.

Human hepatocytes: isolation, culture, and quality procedures.

Green tea protects human osteoblasts from cigarette smoke-induced injury: possible clinical implication.

Quercetin protects primary human osteoblasts exposed to cigarette smoke through activation of the antioxidative enzymes HO-1 and SOD-1.

The microenvironment in the Hirschsprung's disease gut supports myenteric plexus growth.

Monocytes do not transdifferentiate into proper osteoblasts.

EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepatocyte-like cells.

Hyperinsulinemia reduces osteoblast activity in vitro via upregulation of TGF-β.

Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?

Response to the "enhancement of human peripheral blood mononuclear cell transplantation-mediated bone formation" by Yang et al.

Modeling hepatic osteodystrophy in Abcb4 deficient mice.

Darbepoetin inhibits proliferation of hepatic cancer cells in the presence of TGF-β.

Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics.

Therapeutic peritoneal lavage with warm saline solution as an option for a critical hypothermic trauma patient.

Chronic CCl4 intoxication causes liver and bone damage similar to the human pathology of hepatic osteodystrophy: a mouse model to analyse the liver-bone axis.

5-azacytidine improves the osteogenic differentiation potential of aged human adipose-derived mesenchymal stem cells by DNA demethylation.

The right choice of antihypertensives protects primary human hepatocytes from ethanol- and recombinant human TGF-β1-induced cellular damage.

Increased oxidative stress response in granulocytes from older patients with a hip fracture may account for slow regeneration.

Factors circulating in the blood of type 2 diabetes mellitus patients affect osteoblast maturation - description of a novel in vitro model.

Pluripotency gene expression and growth control in cultures of peripheral blood monocytes during their conversion into programmable cells of monocytic origin (PCMO): evidence for a regulatory role of autocrine activin and TGF-β.

Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.

Crucial Role of Vitamin D in the Musculoskeletal System.

BMP9 a possible alternative drug for the recently withdrawn BMP7? New perspectives for (re-)implementation by personalized medicine.

Distinct Gene Expression Patterns Defining Human Osteoblasts' Response to BMP2 Treatment: Is the Therapeutic Success All a Matter of Timing?