Lucie Parent

Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channel.

Outer pore topology of the ECaC-TRPV5 channel by cysteine scan mutagenesis.

[Nobel Prize for Chemistry 2003. Water channels and ionic channels].

Negatively charged residues in the N-terminal of the AID helix confer slow voltage dependent inactivation gating to CaV1.2.

New insights on the voltage dependence of the KCa3.1 channel block by internal TBA.

The C-terminal residues in the alpha-interacting domain (AID) helix anchor CaV beta subunit interaction and modulation of CaV2.3 channels.

A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels.

The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.

Structural determinants of the closed KCa3.1 channel pore in relation to channel gating: results from a substituted cysteine accessibility analysis.

The role of distal S6 hydrophobic residues in the voltage-dependent gating of CaV2.3 channels.

Topology of the selectivity filter of a TRPV channel: rapid accessibility of contiguous residues from the external medium.

Hydrophobic interactions as key determinants to the KCa3.1 channel closed configuration. An analysis of KCa3.1 mutants constitutively active in zero Ca2+.

Inhibition of the KCa3.1 channels by AMP-activated protein kinase in human airway epithelial cells.

Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies.

Molecular determinants of the CaVbeta-induced plasma membrane targeting of the CaV1.2 channel.

Toward the rational design of constitutively active KCa3.1 mutant channels.

Double mutant cycle analysis identified a critical leucine residue in the IIS4S5 linker for the activation of the Ca(V)2.3 calcium channel.

The C-terminus of human Ca(v)2.3 voltage-gated calcium channel interacts with alternatively spliced calmodulin-2 expressed in two human cell lines.

A quartet of leucine residues in the guanylate kinase domain of CaVβ determines the plasma membrane density of the CaV2.3 channel.

Contribution of the KCa3.1 channel-calmodulin interactions to the regulation of the KCa3.1 gating process.

Cooperative activation of the T-type CaV3.2 channel: interaction between Domains II and III.

Aromatic-aromatic interactions between residues in KCa3.1 pore helix and S5 transmembrane segment control the channel gating process.

Functional characterization of CaVα2δ mutations associated with sudden cardiac death.

Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity.