Gary Splitter

Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis.

Encephalomyocarditis and Mengo viruses productively infect murine T-lymphocyte cell lines but not fresh ex vivo derived T lymphocytes.

Molecular and immunological characterisation of recombinant Brucella abortus glyceraldehyde-3-phosphate-dehydrogenase, a T- and B-cell reactive protein that induces partial protection when co-administered with an interleukin-12-expressing plasmid in a DNA vaccine formulation.

Identification and characterization of a Brucella abortus ATP-binding cassette transporter homolog to Rhizobium meliloti ExsA and its role in virulence and protection in mice.

Molecular and cellular interactions between Brucella abortus antigens and host immune responses.

Virulence criteria for Brucella abortus strains as determined by interferon regulatory factor 1-deficient mice.

Rough lipopolysaccharide from Brucella abortus and Escherichia coli differentially activates the same mitogen-activated protein kinase signaling pathways for tumor necrosis factor alpha in RAW 264.7 macrophage-like cells.

Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans.

Microarray analysis of mRNA levels from RAW264.7 macrophages infected with Brucella abortus.

The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.

Role of Toll-like receptor 4 in induction of cell-mediated immunity and resistance to Brucella abortus infection in mice.

Bovine herpesvirus tegument protein VP22 enhances thymidine kinase/ganciclovir suicide gene therapy for neuroblastomas compared to herpes simplex virus VP22.

Comparative whole-genome hybridization reveals genomic islands in Brucella species.

Comparison of bovine leukemia virus (BLV) and CMV promoter-driven reporter gene expression in BLV-infected and non-infected cells.

Denitrification genes regulate Brucella virulence in mice.

The role of integrase/recombinase xerD and monofunctional biosynthesis peptidoglycan transglycosylase genes in the pathogenicity of Brucella abortus infection in vitro and in vivo.

Isolation of Brucella abortus total RNA from B. abortus-infected murine RAW macrophages.

Bovine herpesvirus VP22 induces apoptosis in neuroblastoma cells by upregulating the expression ratio of Bax to Bcl-2.

Nuclear and mitochondrial localization signals overlap within bovine herpesvirus 1 tegument protein VP22.

Enhancement of antigen acquisition by dendritic cells and MHC class II-restricted epitope presentation to CD4+ T cells using VP22 DNA vaccine vectors that promote intercellular spreading following initial transfection.

Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections.

Unraveling Brucella genomics and pathogenesis in immunocompromised IRF-1-/- mice.

Attenuated bioluminescent Brucella melitensis mutants GR019 (virB4), GR024 (galE), and GR026 (BMEI1090-BMEI1091) confer protection in mice.

CGHScan: finding variable regions using high-density microarray comparative genomic hybridization data.

DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B- and T-cell responses in outbred animals.

Brucella: functional genomics and host-pathogen interactions.

Blue-light-activated histidine kinases: two-component sensors in bacteria.

DNA recognition properties of the cell-to-cell movement protein (MP) of soybean isolate of Mungbean yellow mosaic India virus (MYMIV-Sb).

Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella.

Genomic island 2 of Brucella melitensis is a major virulence determinant: functional analyses of genomic islands.

TBK1 does not play a role in the control of in vitro Burkholderia pseudomallei growth.

Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella.

Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP.

Brucella regulators: self-control in a hostile environment.

Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo.

Brucella melitensis, B. neotomae and B. ovis elicit common and distinctive macrophage defense transcriptional responses.

Biochemical and functional analysis of TIR domain containing protein from Brucella melitensis.

Modulation of microtubule dynamics by a TIR domain protein from the intracellular pathogen Brucella melitensis.

Brucella melitensis cyclic di-GMP phosphodiesterase BpdA controls expression of flagellar genes.