Department of Surgery,
Trauma and Transfusion Medicine Research Center,
Trauma and Transfusion Medicine Research Center, Department of Surgery
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Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions.
The Journal of biological chemistry Jun, 2004 | Pubmed ID: 15169791
Preinjury statin use is associated with a higher risk of multiple organ failure after injury: a propensity score adjusted analysis.
The Journal of trauma Sep, 2009 | Pubmed ID: 19741387
The use of pre-operative imaging and intraoperative parathyroid hormone level to guide surgical management of tertiary hyperparathyroidism from X-linked hypophosphatemic rickets: a case report.
Cases journal Sep, 2009 | Pubmed ID: 19918472
Tension pneumopericardium in an infant.
Surgery Mar, 2011 | Pubmed ID: 19962168
Extracellular high mobility group box-1 (HMGB1) inhibits enterocyte migration via activation of Toll-like receptor-4 and increased cell-matrix adhesiveness.
The Journal of biological chemistry Feb, 2010 | Pubmed ID: 20007974
Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium.
Gastroenterology Sep, 2010 | Pubmed ID: 20580721
Intestinal stem cells and their roles during mucosal injury and repair.
The Journal of surgical research May, 2011 | Pubmed ID: 20599211
DNA attenuates enterocyte Toll-like receptor 4-mediated intestinal mucosal injury after remote trauma.
American journal of physiology. Gastrointestinal and liver physiology May, 2011 | Pubmed ID: 21233273
Over reliance on computed tomography imaging in patients with severe abdominal injury: is the delay worth the risk?
The Journal of trauma Feb, 2011 | Pubmed ID: 21307722
An appraisal of endoscopic retrograde cholangiopancreatography (ERCP) for pancreaticobiliary disease in children: our institutional experience in 231 cases.
Surgical endoscopy Aug, 2011 | Pubmed ID: 21359895
Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease.
Annals of surgery Sep, 2011 | Pubmed ID: 21865943
Intracellular heat shock protein-70 negatively regulates TLR4 signaling in the newborn intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) May, 2012 | Pubmed ID: 22461698
Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way.
The journal of trauma and acute care surgery Apr, 2012 | Pubmed ID: 22491601
Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22733781
Massive transfusion: an evidence-based review of recent developments.
Archives of surgery (Chicago, Ill. : 1960) Jun, 2012 | Pubmed ID: 22786545
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice.
Gastroenterology Sep, 2012 | Pubmed ID: 22796522
Endoscopic retrograde cholangiopancreatography is safe and effective for the diagnosis and treatment of pancreaticobiliary disease following abdominal organ transplant in children.
Pediatric transplantation Dec, 2012 | Pubmed ID: 22905881
Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis.
The Journal of biological chemistry Oct, 2012 | Pubmed ID: 22955282
Innate immune activation after transfusion of stored red blood cells.
Transfusion medicine reviews Apr, 2013 | Pubmed ID: 23434246
A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2013 | Pubmed ID: 23455503
Use of a massive transfusion protocol in nontrauma patients: activate away.
Journal of the American College of Surgeons Jun, 2013 | Pubmed ID: 23571144
Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS-NO-nitrite signaling.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2013 | Pubmed ID: 23650378
Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors.
PloS one , 2013 | Pubmed ID: 23776545
Simultaneous extracorporeal membrane oxygenation and therapeutic plasma exchange procedures are tolerable in both pediatric and adult patients.
Transfusion Apr, 2014 | Pubmed ID: 24117674
Prehospital use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of trauma-induced coagulopathy.
Annals of surgery Aug, 2014 | Pubmed ID: 24424149
Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.
The Journal of biological chemistry Apr, 2014 | Pubmed ID: 24519940
A novel scoring system to predict the development of necrotizing enterocolitis totalis in premature infants.
Journal of pediatric surgery Jul, 2014 | Pubmed ID: 24952787
Toll-like receptor 4 regulates platelet function and contributes to coagulation abnormality and organ injury in hemorrhagic shock and resuscitation.
Circulation. Cardiovascular genetics Oct, 2014 | Pubmed ID: 25049041
Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps.
Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors January-March, 2015 | Pubmed ID: 25076119
X chromosome-linked IRAK-1 polymorphism is a strong predictor of multiple organ failure and mortality postinjury.
Annals of surgery Oct, 2014 | Pubmed ID: 25203887
Massive transfusion protocol activation does not result in preferential use of older red blood cells.
Journal of blood transfusion , 2014 | Pubmed ID: 25295222
Taking the Blood Bank to the Field: The Design and Rationale of the Prehospital Air Medical Plasma (PAMPer) Trial.
Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors Jul-Sep, 2015 | Pubmed ID: 25658881
Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4).
Tetrahedron letters Jun, 2015 | Pubmed ID: 26236050
Platelet-derived HMGB1 is a critical mediator of thrombosis.
The Journal of clinical investigation Dec, 2015 | Pubmed ID: 26551681
Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes.
Biochemical and biophysical research communications Sep, 2016 | Pubmed ID: 27449608
Dysbiosis Across Multiple Body Sites in Critically Ill Adult Surgical Patients.
Shock (Augusta, Ga.) Dec, 2016 | Pubmed ID: 27454385
Aged Human Stored Red Blood Cell Supernatant Inhibits Macrophage Phagocytosis in an HMGB1 Dependent Manner After Trauma in a Murine Model.
Shock (Augusta, Ga.) Feb, 2017 | Pubmed ID: 27488090
The confusion continues: results from an American Association for the Surgery of Trauma survey on massive transfusion practices among United States trauma centers.
Transfusion Oct, 2016 | Pubmed ID: 27515056
Abnormalities in fibrinolysis at the time of admission are associated with deep vein thrombosis, mortality, and disability in a pediatric trauma population.
The journal of trauma and acute care surgery Jan, 2017 | Pubmed ID: 27779597
Platelet Transfusion in Critical Care and Surgery: Evidence-Based Review of Contemporary Practice and Future Directions.
Shock (Augusta, Ga.) May, 2017 | Pubmed ID: 27849676
Surgical rescue: The next pillar of acute care surgery.
The journal of trauma and acute care surgery Feb, 2017 | Pubmed ID: 27893639
In vitro characterization of SynthoPlate™ (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice.
Journal of thrombosis and haemostasis : JTH Feb, 2017 | Pubmed ID: 27925685
Management of anticoagulation with rivaroxaban in trauma and acute care surgery: Complications and reversal strategies as compared to warfarin therapy.
The journal of trauma and acute care surgery Mar, 2017 | Pubmed ID: 28045742
Is Coagulopathy an Appropriate Therapeutic Target During Critical Illness Such as Trauma or Sepsis?
Shock (Augusta, Ga.) Feb, 2017 | Pubmed ID: 28234791
Should All Massively Transfused Patients Be Treated Equally? An Analysis of Massive Transfusion Ratios in the Nontrauma Setting.
Critical care medicine Aug, 2017 | Pubmed ID: 28537938
Trending Fibrinolytic Dysregulation: Fibrinolysis Shutdown in the Days After Injury Is Associated With Poor Outcome in Severely Injured Children.
Annals of surgery Sep, 2017 | Pubmed ID: 28650356
Precision Correction of Coagulopathy or Prothrombin Complex Concentrates?: Reversal Options for Dabigatran following Trauma.
Anesthesiology Nov, 2017 | Pubmed ID: 28857805
Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.
Thrombosis and haemostasis Oct, 2017 | Pubmed ID: 28981554
Principal component analysis of coagulation assays in severely injured children.
Surgery Apr, 2018 | Pubmed ID: 29248181
Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA.
Scientific reports Feb, 2018 | Pubmed ID: 29391442
Overresuscitation with plasma is associated with sustained fibrinolysis shutdown and death in pediatric traumatic brain injury.
The journal of trauma and acute care surgery Jul, 2018 | Pubmed ID: 29443859
Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage.
Scientific reports Feb, 2018 | Pubmed ID: 29449604
Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis.
The journal of trauma and acute care surgery Jun, 2018 | Pubmed ID: 29538234
Platelet HMGB1 is required for efficient bacterial clearance in intra-abdominal bacterial sepsis in mice.
Blood advances Mar, 2018 | Pubmed ID: 29563120
Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes.
Oxidative medicine and cellular longevity , 2018 | Pubmed ID: 29849867
A qualitative study of gender differences in the experiences of general surgery trainees.
The Journal of surgical research Aug, 2018 | Pubmed ID: 29907201
Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps.
BMC cancer Jun, 2018 | Pubmed ID: 29929491
Blunt cerebrovascular injury in elderly fall patients: are we screening enough?
World journal of emergency surgery : WJES , 2018 | Pubmed ID: 29997683
Design and implementation of the Western Pennsylvania regional Stop the Bleed initiative.
The journal of trauma and acute care surgery Oct, 2018 | Pubmed ID: 30020225
Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock.
The New England journal of medicine Jul, 2018 | Pubmed ID: 30044935
ADAMTS13: origins, applications, and prospects.
Transfusion Oct, 2018 | Pubmed ID: 30208220
Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism.
The journal of trauma and acute care surgery Jan, 2019 | Pubmed ID: 30239375
Reversing anti-factor Xa agents and the unmet needs in trauma patients.
Blood Dec, 2018 | Pubmed ID: 30309890
Bacterial contamination of platelets for transfusion: strategies for prevention.
Critical care (London, England) Oct, 2018 | Pubmed ID: 30367640
Risk of Venous Thromboembolism for Patients with Pancreatic Ductal Adenocarcinoma Undergoing Preoperative Chemotherapy Followed by Surgical Resection.
Annals of surgical oncology May, 2019 | Pubmed ID: 30652227
A Systematic Review of Gender-Based Differences in Hirsch Index Among Academic Surgeons.
The Journal of surgical research Apr, 2019 | Pubmed ID: 30694759
Perceptions Regarding Mentorship Among General Surgery Trainees With Academic Career Intentions.
Journal of surgical education , 2019 | Pubmed ID: 30704954
Implementation of a prehospital air medical thawed plasma program: Is it even feasible?
The journal of trauma and acute care surgery Nov, 2019 | Pubmed ID: 31205211
Early versus late venous thromboembolism: A secondary analysis of data from the PROPPR trial.
Surgery Sep, 2019 | Pubmed ID: 31230842
Platelet-derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice.
Journal of thrombosis and haemostasis : JTH Oct, 2019 | Pubmed ID: 31294514
Pass interference: Getting in the way of platelets.
Journal of thrombosis and haemostasis : JTH Sep, 2019 | Pubmed ID: 31301115
Window of Opportunity to Mitigate Trauma-induced Coagulopathy: Fibrinolysis Shutdown not Prevalent Until 1 Hour Post-injury.
Annals of surgery Sep, 2019 | Pubmed ID: 31305285
Fibrinolysis Shutdown in Trauma: Historical Review and Clinical Implications.
Anesthesia and analgesia Sep, 2019 | Pubmed ID: 31425218
Platelet Extracellular Vesicles Drive Inflammasome-IL-1β-Dependent Lung Injury in Sickle Cell Disease.
American journal of respiratory and critical care medicine 01, 2020 | Pubmed ID: 31498653
Prehospital plasma in injured patients is associated with survival principally in blunt injury: Results from two randomized prehospital plasma trials.
The journal of trauma and acute care surgery Jan, 2020 | Pubmed ID: 31524836
A comparison between the TEG 6s and TEG 5000 analyzers to assess coagulation in trauma patients.
The journal of trauma and acute care surgery Feb, 2020 | Pubmed ID: 31738314
Correlation of Thromboelastography with Apparent Rivaroxaban Concentration: Has Point-of-Care Testing Improved?
Anesthesiology Feb, 2020 | Pubmed ID: 31939843
Alterations in platelet behavior after major trauma: adaptive or maladaptive?
Platelets Apr, 2021 | Pubmed ID: 31986948
Accelerating availability of clinically-relevant parameter estimates from thromboelastogram point-of-care device.
The journal of trauma and acute care surgery May, 2020 | Pubmed ID: 32032282
Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH.
Journal of thrombosis and haemostasis : JTH Mar, 2020 | Pubmed ID: 32112533
A systematic review and meta-analysis of traumatic intracranial hemorrhage in patients taking prehospital antiplatelet therapy: Is there a role for platelet transfusions?
The journal of trauma and acute care surgery Jun, 2020 | Pubmed ID: 32118818
Massive transfusion and the response to prehospital plasma: It is all in how you define it.
The journal of trauma and acute care surgery Jul, 2020 | Pubmed ID: 32118820
Prehospital plasma is associated with distinct biomarker expression following injury.
JCI insight Apr, 2020 | Pubmed ID: 32229722
Association Between Preoperative Metformin Exposure and Postoperative Outcomes in Adults With Type 2 Diabetes.
JAMA surgery Jun, 2020 | Pubmed ID: 32267474
Forgot calcium? Admission ionized-calcium in two civilian randomized controlled trials of prehospital plasma for traumatic hemorrhagic shock.
The journal of trauma and acute care surgery May, 2020 | Pubmed ID: 32317575
Venous thromboembolism after tranexamic acid administration: legitimate risk or statistical confounder?
ANZ journal of surgery Apr, 2020 | Pubmed ID: 32339430
Whole-Blood Resuscitation of Injured Patients: Innovating from the Past.
JAMA surgery Aug, 2020 | Pubmed ID: 32401295
Effects of Gender Bias and Stereotypes in Surgical Training: A Randomized Clinical Trial.
JAMA surgery Jul, 2020 | Pubmed ID: 32432669
Traumatic injury results in prolonged circulation of ultralarge von Willebrand factor and a reduction in ADAMTS13 activity.
Transfusion Jun, 2020 | Pubmed ID: 32441353
Characterization of unexpected survivors following a prehospital plasma randomized trial.
The journal of trauma and acute care surgery Nov, 2020 | Pubmed ID: 32472902
High-School Students Can Stop the Bleed: A Randomized, Controlled Educational Trial.
Academic pediatrics Mar, 2021 | Pubmed ID: 32473216
Von Willebrand factor as a thrombotic and inflammatory mediator in critical illness.
Transfusion Jun, 2020 | Pubmed ID: 32478907
The great platelet paradox: evolution of platelet contribution to hemostasis, inflammation, and thrombosis after injury.
Blood advances Jun, 2020 | Pubmed ID: 32516417
Hepatic Surgical Stress Promotes Systemic Immunothrombosis That Results in Distant Organ Injury.
Frontiers in immunology , 2020 | Pubmed ID: 32528475
Intravascular hemolysis triggers ADP-mediated generation of platelet-rich thrombi in pre-capillary pulmonary arterioles.
JCI insight Jun, 2020 | Pubmed ID: 32544100
Defining a Research Agenda for Layperson Prehospital Hemorrhage Control: A Consensus Statement.
JAMA network open Jul, 2020 | Pubmed ID: 32663307
Platelet-Monocyte Aggregates: Understanding Mechanisms and Functions in Sepsis.
Shock (Augusta, Ga.) Feb, 2021 | Pubmed ID: 32694394
Pharmacologic Prehabilitation-What About "the Polypill"?
JAMA surgery Nov, 2020 | Pubmed ID: 32805047
The New Zealand white rabbit animal model of acute radiation syndrome: hematopoietic and coagulation-based parameters by radiation dose following supportive care.
International journal of radiation biology , 2021 | Pubmed ID: 32909860
Whole Blood is Superior to Component Transfusion for Injured Children: A Propensity Matched Analysis.
Annals of surgery Oct, 2020 | Pubmed ID: 32932312
Patient and surrogate attitudes via an interviewer-administered survey on exception from informed consent enrollment in the Prehospital Air Medical Plasma (PAMPer) trial.
BMC emergency medicine Oct, 2020 | Pubmed ID: 33004018
Tranexamic Acid During Prehospital Transport in Patients at Risk for Hemorrhage After Injury: A Double-blind, Placebo-Controlled, Randomized Clinical Trial.
JAMA surgery Oct, 2020 | Pubmed ID: 33016996
Whole-Blood Resuscitation of Injured Patients' Plasma.
JAMA surgery Jan, 2021 | Pubmed ID: 33052388
Association of Prehospital Plasma With Survival in Patients With Traumatic Brain Injury: A Secondary Analysis of the PAMPer Cluster Randomized Clinical Trial.
JAMA network open Oct, 2020 | Pubmed ID: 33057642
Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials.
Annals of surgery Mar, 2021 | Pubmed ID: 33065652
Viscoelastic monitoring in trauma resuscitation.
Transfusion Oct, 2020 | Pubmed ID: 33089933
Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness.
Research square Jan, 2021 | Pubmed ID: 33442677
Coupled Model of Blood Volume and Activated Clotting Factor Concentration during Childbirth.
IFAC-PapersOnLine , 2018 | Pubmed ID: 33598665
Age of thawed plasma does not affect clinical outcomes or biomarker expression in patients receiving prehospital thawed plasma: a PAMPer secondary analysis.
Trauma surgery & acute care open , 2021 | Pubmed ID: 33634214
Injured recipients of low-titer group O whole blood have similar clinical outcomes compared to recipients of conventional component therapy: A single-center, retrospective study.
Transfusion Jun, 2021 | Pubmed ID: 33811640
Trauma-induced coagulopathy.
Nature reviews. Disease primers Apr, 2021 | Pubmed ID: 33927200
Early Prehospital Tranexamic Acid Following Injury Is Associated With a 30-day Survival Benefit: A Secondary Analysis of a Randomized Clinical Trial.
Annals of surgery Sep, 2021 | Pubmed ID: 34132695
Does routine postoperative contrast radiography improve outcomes for patients with perforated peptic ulcer? A multicenter retrospective cohort study.
Surgery Nov, 2021 | Pubmed ID: 34175115
Anti-D alloimmunization in Rh(D) negative adults with severe traumatic injury.
Transfusion Jul, 2021 | Pubmed ID: 34269429
Preventing Thrombohemorrhagic Complications of Heparinized COVID-19 Patients Using Adjunctive Thromboelastography: A Retrospective Study.
Journal of clinical medicine Jul, 2021 | Pubmed ID: 34300263
Utilizing natural language processing in the diagnosis and treatment of venous thromboembolism.
Surgery Oct, 2021 | Pubmed ID: 34325905
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
The New England journal of medicine Aug, 2021 | Pubmed ID: 34351721
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19.
The New England journal of medicine Aug, 2021 | Pubmed ID: 34351722
The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation.
Platelets May, 2022 | Pubmed ID: 34369848
Bioinspired artificial platelets: past, present and future.
Platelets Jan, 2022 | Pubmed ID: 34455908
Platelets amplify endotheliopathy in COVID-19.
Science advances Sep, 2021 | Pubmed ID: 34516880
Platelet HMGB1 in Platelet-Rich Plasma (PRP) promotes tendon wound healing.
PloS one , 2021 | Pubmed ID: 34529657
The emerging therapeutic potential of extracellular vesicles in trauma.
Journal of leukocyte biology Jan, 2022 | Pubmed ID: 34533241
Evaluating the Cost-effectiveness of Prehospital Plasma Transfusion in Unstable Trauma Patients: A Secondary Analysis of the PAMPer Trial.
JAMA surgery Dec, 2021 | Pubmed ID: 34550318
Rapid detection of platelet inhibition and dysfunction in traumatic brain injury: A prospective observational study.
The journal of trauma and acute care surgery Jan, 2022 | Pubmed ID: 34629458
The Epidemiology of Extremity Threat and Amputation after Vasopressor-Dependent Sepsis.
Annals of the American Thoracic Society Apr, 2022 | Pubmed ID: 34644242
Reduced cleavage of von willebrand factor by ADAMTS13 is associated with microangiopathic acute kidney injury following trauma.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis Jan, 2022 | Pubmed ID: 34889809
The Pathobiological Basis for Thrombotic Complications in COVID-19: a Review of the Literature.
Current pathobiology reports , 2021 | Pubmed ID: 34900401
Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses.
Cell reports. Medicine Dec, 2021 | Pubmed ID: 35028617
Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19: A Randomized Clinical Trial.
JAMA Jan, 2022 | Pubmed ID: 35040887
Hemorrhagic Resuscitation Guided by Viscoelastography in Far-Forward Combat and Austere Civilian Environments: Goal-Directed Whole-Blood and Blood-Component Therapy Far from the Trauma Center.
Journal of clinical medicine Jan, 2022 | Pubmed ID: 35054050
Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding.
Science translational medicine Jan, 2022 | Pubmed ID: 35080915
The National Blood Shortage-An Impetus for Change.
Annals of surgery Apr, 2022 | Pubmed ID: 35081570
Prehospital low titer group O whole blood is feasible and safe: Results of a prospective randomized pilot trial.
The journal of trauma and acute care surgery May, 2022 | Pubmed ID: 35081595
Low Titer Group O Whole Blood In Injured Children Requiring Massive Transfusion.
Annals of surgery Apr, 2023 | Pubmed ID: 35129530
Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices.
Journal of clinical medicine Feb, 2022 | Pubmed ID: 35160311
Investigation into the Cost-Effectiveness of Extended Posttraumatic Thromboprophylaxis.
Journal of the American College of Surgeons Jan, 2022 | Pubmed ID: 35213466
Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
JAMA Apr, 2022 | Pubmed ID: 35315874
Neutrophil extracellular traps regulate ischemic stroke brain injury.
The Journal of clinical investigation May, 2022 | Pubmed ID: 35358095
Prehospital synergy: Tranexamic acid and blood transfusion in patients at risk for hemorrhage.
The journal of trauma and acute care surgery Jul, 2022 | Pubmed ID: 35393385
Author Correction: Trauma-induced coagulopathy.
Nature reviews. Disease primers Apr, 2022 | Pubmed ID: 35459275
Immuno-Thrombotic Complications of COVID-19: Implications for Timing of Surgery and Anticoagulation.
Frontiers in surgery , 2022 | Pubmed ID: 35599794
An adaptive platform trial for evaluating treatments in patients with life-threatening hemorrhage from traumatic injuries: Planning and execution.
Transfusion Aug, 2022 | Pubmed ID: 35748672
Platelet dysfunction after trauma: From mechanisms to targeted treatment.
Transfusion Aug, 2022 | Pubmed ID: 35748694
Emerging clinical trial designs may accelerate translation in hematology: lessons from COVID-19.
Blood advances Aug, 2022 | Pubmed ID: 35764486
Toward a more complete understanding of who will benefit from prehospital transfusion.
Transfusion Aug, 2022 | Pubmed ID: 35796302
Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress.
Research and practice in thrombosis and haemostasis Jul, 2022 | Pubmed ID: 35814801
Association Between Time to Source Control in Sepsis and 90-Day Mortality.
JAMA surgery Sep, 2022 | Pubmed ID: 35830181
Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an α-antitrypsin-derived peptide motif.
Nature nanotechnology Sep, 2022 | Pubmed ID: 35851383
High Dimensional Multiomics Reveals Unique Characteristics of Early Plasma Administration in Polytrauma Patients With TBI.
Annals of surgery Oct, 2022 | Pubmed ID: 35861072
Platelet-Inspired Intravenous Nanomedicine for Injury-Targeted Direct Delivery of Thrombin to Augment Hemostasis in Coagulopathies.
ACS nano Oct, 2022 | Pubmed ID: 35916497
Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients.
Metabolites Aug, 2022 | Pubmed ID: 36144179
Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness.
Seminars in thrombosis and hemostasis Oct, 2022 | Pubmed ID: 36174604
Proteomics of Coagulopathy Following Injury Reveals Limitations of Using Laboratory Assessment to Define Trauma-Induced Coagulopathy to Predict Massive Transfusion.
Annals of surgery open : perspectives of surgical history, education, and clinical approaches Jun, 2022 | Pubmed ID: 36177090
Lipidomic signatures align with inflammatory patterns and outcomes in critical illness.
Nature communications Nov, 2022 | Pubmed ID: 36357394
EFFECT OF IRRIGATION FLUID COMPOSITION ON HEMOSTASIS IN MOUSE BLEEDING MODELS.
Shock (Augusta, Ga.) Dec, 2022 | Pubmed ID: 36399097
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
JAMA Jan, 2023 | Pubmed ID: 36525245
Plasma proteomics reveals early, broad release of chemokine, cytokine, TNF, and interferon mediators following trauma with delayed increases in a subset of chemokines and cytokines in patients that remain critically ill.
Frontiers in immunology , 2022 | Pubmed ID: 36532045
MACROPHAGE SWITCHING: POLARIZATION AND MOBILIZATION AFTER TRAUMA.
Shock (Augusta, Ga.) Feb, 2023 | Pubmed ID: 36669229
Evaluation of critical care burden following traumatic injury from two randomized controlled trials.
Scientific reports Jan, 2023 | Pubmed ID: 36670216
Anticoagulation in adult patients supported with extracorporeal membrane oxygenation: guidance from the Scientific and Standardization Committees on Perioperative and Critical Care Haemostasis and Thrombosis of the International Society on Thrombosis and Haemostasis.
Journal of thrombosis and haemostasis : JTH Feb, 2023 | Pubmed ID: 36700496
High-dimensional proteomics identifies organ injury patterns associated with outcomes in human trauma.
The journal of trauma and acute care surgery Jun, 2023 | Pubmed ID: 36787435
Long-term Outcomes of Parastomal Hernia Repair-The Defect in Knowledge (and Abdominal Wall) Remains.
JAMA surgery Apr, 2023 | Pubmed ID: 36790802
Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19.
JAMA Apr, 2023 | Pubmed ID: 36942550
Effects of the circulating environment of COVID-19 on platelet and neutrophil behavior.
Frontiers in immunology , 2023 | Pubmed ID: 36999030
Hemostatic In Vitro Properties of Novel Plasma Supernatants Produced from Late-storage Low-titer Type O Whole Blood.
Anesthesiology Jul, 2023 | Pubmed ID: 37027803
A rapid ABO and RhD test demonstrates high fidelity to blood bank testing for RhD typing.
Transfusion May, 2023 | Pubmed ID: 37067381
Prehospital tranexamic acid is associated with a dose-dependent decrease in syndecan-1 after trauma: A secondary analysis of a prospective randomized trial.
The journal of trauma and acute care surgery Nov, 2023 | Pubmed ID: 37125811
Early lyophilized cryoprecipitate enhances the ADAMTS13/VWF ratio to reduce systemic endotheliopathy and lessen lung injury in a mouse multiple-trauma hemorrhage model.
The journal of trauma and acute care surgery Aug, 2023 | Pubmed ID: 37211640
Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.
JAMA network open May, 2023 | Pubmed ID: 37227729
Effect of the P-Selectin Inhibitor Crizanlizumab on Survival Free of Organ Support in Patients Hospitalized for COVID-19: A Randomized Controlled Trial.
Circulation Aug, 2023 | Pubmed ID: 37356038
High Dose of Metformin Decreases Susceptibility to Occlusive Arterial Thrombosis in Diabetic Mice.
Research square Jul, 2023 | Pubmed ID: 37503167
Mechanisms and management of the coagulopathy of trauma and sepsis: trauma-induced coagulopathy, sepsis-induced coagulopathy, and disseminated intravascular coagulation.
Journal of thrombosis and haemostasis : JTH Dec, 2023 | Pubmed ID: 37722532
Effect of therapeutic-dose heparin on severe acute kidney injury and death in noncritically ill patients hospitalized for COVID-19: a prespecified secondary analysis of the ACTIV4a and ATTACC randomized trial.
Research and practice in thrombosis and haemostasis Aug, 2023 | Pubmed ID: 37727846
Evaluating potential disparities in geospatial access to American College of Surgeons/American Association for the Surgery of Trauma-verified emergency general surgery centers.
The journal of trauma and acute care surgery Feb, 2024 | Pubmed ID: 37751150
Precision in Transfusion Medicine.
JAMA Nov, 2023 | Pubmed ID: 37824169
Effects of inflammation on thrombosis and outcomes in COVID-19: secondary analysis of the ATTACC/ACTIV-4a trial.
Research and practice in thrombosis and haemostasis Oct, 2023 | Pubmed ID: 37854455
Simvastatin in Critically Ill Patients with Covid-19.
The New England journal of medicine Oct, 2023 | Pubmed ID: 37888913
High Dose of Metformin Decreases Susceptibility to Occlusive Arterial Thrombosis in Diabetic Mice.
Journal of pharmacy and pharmacology research , 2023 | Pubmed ID: 37975061
Symptoms and Impaired Quality of Life After COVID-19 Hospitalization: Effect of Therapeutic Heparin in Non-ICU Patients in the Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 Acute Trial: Effect on 3-Month Symptoms and Quality of Life.
Chest Apr, 2024 | Pubmed ID: 37979717
Platelet-inspired synthetic nanoparticles improve hemostasis and hemodynamics in a rabbit model of abdominal hemorrhage.
The journal of trauma and acute care surgery Jan, 2024 | Pubmed ID: 38057963
Long wavelength light exposure reduces systemic inflammation coagulopathy and acute organ injury following multiple injuries in mice.
The journal of trauma and acute care surgery Jun, 2024 | Pubmed ID: 38079258
Restoring glucose balance: Conditional HMGB1 knockdown mitigates hyperglycemia in a Streptozotocin induced mouse model.
Heliyon Jan, 2024 | Pubmed ID: 38187339
Contemporary management of major haemorrhage in critical care.
Intensive care medicine Jan, 2024 | Pubmed ID: 38189930
The Hemostatic Resuscitation and Trauma Induced Coagulopathy (HERETIC) meeting: challenging dogma.
Trauma surgery & acute care open , 2024 | Pubmed ID: 38196933
Therapeutic plasma exchange is feasible and tolerable in severely injured patients with trauma-induced coagulopathy.
Trauma surgery & acute care open , 2024 | Pubmed ID: 38196934
Correction: Contemporary management of major haemorrhage in critical care.
Intensive care medicine Mar, 2024 | Pubmed ID: 38285053
Time to First Whole Blood Associated With Survival-First (Whole) Blood?
JAMA surgery Apr, 2024 | Pubmed ID: 38294800
Lung Epithelium Releases Growth Differentiation Factor 15 in Response to Pathogen-mediated Injury.
American journal of respiratory cell and molecular biology May, 2024 | Pubmed ID: 38301257
Mechanism matters: mortality and endothelial cell damage marker differences between blunt and penetrating traumatic injuries across three prehospital clinical trials.
Scientific reports Feb, 2024 | Pubmed ID: 38302619
Transforming research to improve therapies for trauma in the twenty-first century.
Critical care (London, England) Feb, 2024 | Pubmed ID: 38350971
Missingness matters: a secondary analysis of thromboelastography measurements from a recent prehospital randomized tranexamic acid clinical trial.
Trauma surgery & acute care open , 2024 | Pubmed ID: 38375027
Advanced and alternative research methods for the acute care surgeon scientist.
Trauma surgery & acute care open , 2024 | Pubmed ID: 38390469
Tranexamic acid in trauma: After 3 hours from injury, when is it safe and effective to use again?
Transfusion May, 2024 | Pubmed ID: 38461482
Prehospital tranexamic acid is associated with a survival benefit without an increase in complications: Results of two harmonized randomized clinical trials.
The journal of trauma and acute care surgery Nov, 2024 | Pubmed ID: 38523128
Sex dimorphisms in coagulation: Implications in trauma-induced coagulopathy and trauma resuscitation.
American journal of hematology Apr, 2024 | Pubmed ID: 38567625
Four-factor prothrombin complex concentrate is not inferior to andexanet alfa for the reversal or oral factor Xa inhibitors: An Eastern Association for the Surgery of Trauma multicenter study.
The journal of trauma and acute care surgery Oct, 2024 | Pubmed ID: 38685190
Early Cold Stored Platelet Transfusion Following Severe Injury: A Randomized Clinical Trial.
Annals of surgery Aug, 2024 | Pubmed ID: 38708880
Whole Blood and Blood Component Resuscitation in Trauma: Interaction and Association with Mortality.
Annals of surgery May, 2024 | Pubmed ID: 38708894
A comparison of computational algorithms for the Bayesian analysis of clinical trials.
Clinical trials (London, England) Dec, 2024 | Pubmed ID: 38752434
Characterization of adverse events in injured patients at risk of hemorrhagic shock: a secondary analysis of three harmonized prehospital randomized clinical trials.
Trauma surgery & acute care open , 2024 | Pubmed ID: 38933603
Heparin Dose Intensity and Organ Support-Free Days in Patients Hospitalized for COVID-19.
JACC. Advances Mar, 2024 | Pubmed ID: 38938844
Trauma patients have reduced ex vivo flow-dependent platelet hemostatic capacity in a microfluidic model of vessel injury.
PloS one , 2024 | Pubmed ID: 38985805
Association between timing of operative interventions and mortality in emergency general surgery.
Trauma surgery & acute care open , 2024 | Pubmed ID: 39027653
Early GFAP and UCH-L1 point-of-care biomarker measurements for the prediction of traumatic brain injury and progression in patients with polytrauma and hemorrhagic shock.
Journal of neurosurgery May, 2024 | Pubmed ID: 39076152
Effect of sodium-glucose co-transporter-2 inhibitors on survival free of organ support in patients hospitalised for COVID-19 (ACTIV-4a): a pragmatic, multicentre, open-label, randomised, controlled, platform trial.
The lancet. Diabetes & endocrinology Oct, 2024 | Pubmed ID: 39250922
Sodium-glucose co-transporter-2 inhibitors for hospitalised patients with COVID-19: a prospective meta-analysis of randomised trials.
The lancet. Diabetes & endocrinology Oct, 2024 | Pubmed ID: 39250923
TEMPORARY REMOVAL: Alterations in visible light exposure modulate platelet function and regulate thrombus formation.
Journal of thrombosis and haemostasis : JTH Sep, 2024 | Pubmed ID: 39299611
A surface-functionalized whole blood-based dielectric microsensor for assessment of clot firmness in a fibrinolytic environment.
Biosensors & bioelectronics Jan, 2025 | Pubmed ID: 39332249
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