Max Gassmann

Institute of Veterinary Physiology and Zurich Center of Integrative Human Physiology (ZIHP), University of Zurich

Research Area

Medicine

Biography

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JoVE Journal Publications

Article Total : 5	Year
Publication title	2017
Publication title	2017
Publication title	2017
Publication title	2017
Publication title	2018

Other Publications

Article	Year
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes & development\| PubMed ID: 9436976	1998
Erythropoietin modulates intracellular calcium in a human neuroblastoma cell line. The Journal of physiology\| PubMed ID: 10087335	1999
Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3) The Journal of clinical investigation\| PubMed ID: 10712429	2000
Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11027359	2000
From Genetically Altered Mice to Integrative Physiology. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society\| PubMed ID: 11390761	1998
Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 11790723	2002
Copper ion redox state is critical for its effects on ion transport pathways and methaemoglobin formation in trout erythrocytes. Chemico-biological interactions\| PubMed ID: 11803028	2002
Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 11923216	2002
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor. Cancer research\| PubMed ID: 12019179	2002
HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration. Nature medicine\| PubMed ID: 12068288	2002
Cerebral transcriptome analysis of transgenic mice overexpressing erythropoietin. Neuroscience letters\| PubMed ID: 12113907	2002
Extracellular signal-regulated protein kinase activation during reoxygenation is required to restore ischaemia-induced endothelial barrier failure. The Biochemical journal\| PubMed ID: 12137564	2002
DNA-binding activity of hypoxia-inducible factors (HIFs). Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12152189	2002
Pattern of prepro-endothelin-1 expression revealed by reporter-gene activity in kidneys of erythropoietin-overexpressing mice. Clinical science (London, England : 1979)\| PubMed ID: 12193052	2002
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12207001	2002
Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells. Biochemical and biophysical research communications\| PubMed ID: 12237125	2002
Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis. Immunity\| PubMed ID: 12354381	2002
Hypoxic up-regulation of erythroid 5-aminolevulinate synthase. Blood\| PubMed ID: 12393745	2003
Characterization of HIF-1 alpha overexpressing HeLa cells and implications for gene therapy. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP\| PubMed ID: 12458176	2002
Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function... The Journal of biological chemistry\| PubMed ID: 12482866	2003
Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12490547	2003
Ultrasound guided, pre-radiation oxygen measurements using polarographic oxygen needle electrodes in spontaneous canine soft tissue sarcomas. In vivo (Athens, Greece)\| PubMed ID: 12494886	2002
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12514119	2003
Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis. Blood\| PubMed ID: 12576335	2003
Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity. Blood\| PubMed ID: 12750170	2003
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Molecular and cellular biology\| PubMed ID: 12972594	2003
Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN. Molecular and cellular biology\| PubMed ID: 12972598	2003
Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5. The EMBO journal\| PubMed ID: 14517256	2003
Constitutive upregulation of hypoxia-inducible factor-1alpha mRNA occurring in highly metastatic lung carcinoma cells leads to vascular endothelial growth factor overexpression upon hypoxic ... Oncogene\| PubMed ID: 14555985	2003
Molecular mechanisms of oxygen-induced regulation of Na+/K+ pump. Advances in experimental medicine and biology\| PubMed ID: 14635672	2003
Hypoxia and high altitude. The molecular response. Advances in experimental medicine and biology\| PubMed ID: 14713116	2003
Non-erythroid functions of erythropoietin. Advances in experimental medicine and biology\| PubMed ID: 14713131	2003
Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis. Arthritis and rheumatism\| PubMed ID: 14730595	2004
HIFs and tumors--causes and consequences. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 15003941	2004
Differentiating embryonic stem cells into embryoid bodies. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15041757	2004
Oxygenation of spontaneous canine tumors during fractionated radiation therapy. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]\| PubMed ID: 15127160	2004
Simultaneous exposure of rats to dioxin and carbon monoxide reduces the xenobiotic but not the hypoxic response. Biological chemistry\| PubMed ID: 15134343	2004
Rescue of lethal c-KitW/W mice by erythropoietin. Blood\| PubMed ID: 15178584	2004
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circulation research\| PubMed ID: 15178641	2004
Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15215287	2004
High altitude training of dogs results in elevated erythropoietin and endothelin-1 serum levels. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology\| PubMed ID: 15313491	2004
Hypoxia enhances human B19 erythrovirus gene expression in primary erythroid cells. Virology\| PubMed ID: 15327892	2004
HIF-1alpha expression follows microvascular loss in advanced murine adriamycin nephrosis. American journal of physiology. Renal physiology\| PubMed ID: 15383400	2005
HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius. Respiratory physiology & neurobiology\| PubMed ID: 15522704	2004
Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15556972	2005
Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia. Cell transplantation\| PubMed ID: 15789664	2005
Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies. The Journal of physiology\| PubMed ID: 16051624	2005
NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biological chemistry\| PubMed ID: 16164411	2005
Preserved placental oxygenation and development during severe systemic hypoxia. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 16195499	2006
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16207820	2005
Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia. Thrombosis and haemostasis\| PubMed ID: 16268482	2005
Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions. European journal of applied physiology\| PubMed ID: 16284786	2006
The effect of erythropoietin on gentamicin-induced auditory hair cell loss. The Laryngoscope\| PubMed ID: 16467726	2006
Sensing and responding to hypoxia via HIF in model invertebrates. Journal of insect physiology\| PubMed ID: 16500673	2006
Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species. Journal of cell science\| PubMed ID: 16507596	2006
Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 16690772	2006
Regulating cellular oxygen sensing by hydroxylation. Cardiovascular research\| PubMed ID: 16780822	2006
Reduced cerebral blood flow but elevated cerebral glucose metabolic rate in erythropoietin overexpressing transgenic mice with excessive erythrocytosis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 16804549	2007
Permanently increased conductance of the murine uterine arcade after the first pregnancy. European journal of morphology\| PubMed ID: 16982480	2005
The yeast genome may harbor hypoxia response elements (HRE). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP\| PubMed ID: 17035097	2007
Hypoxic preconditioning and erythropoietin protect retinal neurons from degeneration. Advances in experimental medicine and biology\| PubMed ID: 17089884	2006
Hypoxia-induced gene activity in disused oxidative muscle. Advances in experimental medicine and biology\| PubMed ID: 17089889	2006
Excessive erythrocytosis does not elevate capillary oxygen delivery in subcutaneous mouse tissue. Microcirculation (New York, N.Y. : 1994)\| PubMed ID: 17365666	2007
Enhanced erythro-phagocytosis in polycythemic mice overexpressing erythropoietin. Blood\| PubMed ID: 17395782	2007
Simultaneous application of the vascular endothelial growth factor (VEGF) receptor inhibitor PTK787/ZK 222584 and ionizing radiation does not further reduce the growth of canine oral melanom... Veterinary journal (London, England : 1997)\| PubMed ID: 17449301	2007
Erythropoietin enhances immune responses in mice. European journal of immunology\| PubMed ID: 17458859	2007
Enhanced susceptibility to suicidal death of erythrocytes from transgenic mice overexpressing erythropoietin. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 17567717	2007
Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia. The Journal of physiology\| PubMed ID: 17584830	2007
Acute and chronic exposure to hypoxia alters ventilatory pattern but not minute ventilation of mice overexpressing erythropoietin. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 17652365	2007
Oxygen-induced Regulation of Na/K ATPase in cerebellar granule cells. The Journal of general physiology\| PubMed ID: 17893192	2007
Constitutively overexpressed erythropoietin reduces infarct size in a mouse model of permanent coronary artery ligation. Methods in enzymology\| PubMed ID: 17998053	2007
Nociceptive tuning by stem cell factor/c-Kit signaling. Neuron\| PubMed ID: 18054864	2007
Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the b... NeuroImage\| PubMed ID: 18077185	2008
Oxygen supply and retinal function: insights from a transgenic animal model. Advances in experimental medicine and biology\| PubMed ID: 18188942	2008
Abortion in mice with excessive erythrocytosis is due to impaired arteriogenesis of the uterine arcade. Biology of reproduction\| PubMed ID: 18256329	2008
HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam. Brain research\| PubMed ID: 18281021	2008
Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression. Molecular cancer research : MCR\| PubMed ID: 18314489	2008
Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18509100	2008
Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18614764	2008
Placental HIFs as markers of cerebral hypoxic distress in fetal mice. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 18832080	2008
Non-erythroid activities of erythropoietin: Functional effects on murine dendritic cells. Molecular immunology\| PubMed ID: 19027957	2009
Erythropoietin protects from reperfusion-induced myocardial injury by enhancing coronary endothelial nitric oxide production. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 19237290	2009
Sex-dependent regulation of hypoxic ventilation in mice and humans is mediated by erythropoietin. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 19321698	2009
Moderate altitude but not additional endurance training increases markers of oxidative stress in exhaled breath condensate. European journal of applied physiology\| PubMed ID: 19363619	2009
Non-erythroid effects of erythropoietin: are neutrophils a target? Leukemia research\| PubMed ID: 19376577	2009
The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain. Brain & development\| PubMed ID: 19398180	2009
Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain. Brain research\| PubMed ID: 19450570	2009
Erythropoietin activates nitric oxide synthase in murine erythrocytes. American journal of physiology. Cell physiology\| PubMed ID: 19515903	2009
Quantifying Western blots: pitfalls of densitometry. Electrophoresis\| PubMed ID: 19517440	2009
Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1)--invited article. Advances in experimental medicine and biology\| PubMed ID: 19536482	2009
Optimized surgical techniques and postoperative care improve survival rates and permit accurate telemetric recording in exercising mice. BMC veterinary research\| PubMed ID: 19646283	2009
Mast cells and macrophages in duodenal mucosa of mice overexpressing erythropoietin. Journal of anatomy\| PubMed ID: 19691658	2009
The impact of hypoxia on our body: from integrative physiology to human disease. Cellular and molecular life sciences : CMLS\| PubMed ID: 19730799	2009
Erythropoietin modulates the neural control of hypoxic ventilation. Cellular and molecular life sciences : CMLS\| PubMed ID: 19756385	2009
Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear. Cellular and molecular life sciences : CMLS\| PubMed ID: 19763398	2009
The neuronal control of hypoxic ventilation: erythropoietin and sexual dimorphism. Annals of the New York Academy of Sciences\| PubMed ID: 19845617	2009
Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19966291	2010
Erythropoietin treatment leads to reduced blood glucose levels and body mass: insights from murine models. The Journal of endocrinology\| PubMed ID: 20061512	2010
Oxygen-induced regulation of the intracellular glutathione levels in erythrocytes. European journal of applied physiology\| PubMed ID: 20091336	2010
Functional NMDA receptors in rat erythrocytes. American journal of physiology. Cell physiology\| PubMed ID: 20457837	2010
Macrophages as novel target cells for erythropoietin. Haematologica\| PubMed ID: 20595096	2010
Erythropoietin: not just about erythropoiesis. Lancet\| PubMed ID: 20609950	2010
Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 20827262	2011
Impaired ventilatory acclimatization to hypoxia in female mice overexpressing erythropoietin: unexpected deleterious effect of estradiol in carotid bodies. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 20861276	2010
Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 20926767	2010
Cdk5 interacts with Hif-1α in neurons: a new hypoxic signalling mechanism? Brain research\| PubMed ID: 20977891	2011
The role of excessive versus acute administration of erythropoietin in attenuating hepatic ischemia-reperfusion injury. Canadian journal of physiology and pharmacology\| PubMed ID: 21164559	2010
Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain : a journal of neurology\| PubMed ID: 21186263	2011
Erythropoietic and non-erythropoietic functions of erythropoietin in mouse models. The Journal of physiology\| PubMed ID: 21282290	2011
Interventricular heterogeneity in rat heart responses to hypoxia: the tuning of glucose metabolism, ion gradients, and function. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 21398597	2011
Respiratory plasticity in response to changes in oxygen supply and demand. Integrative and comparative biology\| PubMed ID: 21672862	2007
Hypoxia: adapting to high altitude by mutating EPAS-1, the gene encoding HIF-2α. High altitude medicine & biology\| PubMed ID: 21718164	2011
Oxygen 2011. High altitude medicine & biology\| PubMed ID: 21718167	2011
Systemic hypoxia differentially affects neurogenesis during early mouse brain maturation. Brain & development\| PubMed ID: 21824737	2012
Excessive erythrocytosis compromises the blood-endothelium interface in erythropoietin-overexpressing mice. The Journal of physiology\| PubMed ID: 21859826	2011
Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism. Circulation research\| PubMed ID: 21921268	2011
Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression? The Journal of biological chemistry\| PubMed ID: 21930697	2011
Interaction of HIF and USF signaling pathways in human genes flanked by hypoxia-response elements and E-box palindromes. Molecular cancer research : MCR\| PubMed ID: 21984181	2011
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nature medicine\| PubMed ID: 22037645	2011
The impact of hypoxia on cells, mice, and men. High altitude medicine & biology\| PubMed ID: 22429236	2012
AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension. European heart journal\| PubMed ID: 22450430	2014
Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22490927	2012
Acute hypoxia modifies regulation of neuroglobin in the neonatal mouse brain. Experimental neurology\| PubMed ID: 22548980	2012
Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones. European journal of nutrition\| PubMed ID: 22573211	2012
Involvement of oxidative stress in hypoxia-induced blood-brain barrier breakdown. Microvascular research\| PubMed ID: 22668821	2012
Acute and chronic elevation of erythropoietin in the brain improves exercise performance in mice without inducing erythropoiesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22683849	2012
Red blood cell volume and the capacity for exercise at moderate to high altitude. Sports medicine (Auckland, N.Z.)\| PubMed ID: 22741918	2012
S-glutathionylation of the Na,K-ATPase catalytic α subunit is a determinant of the enzyme redox sensitivity. The Journal of biological chemistry\| PubMed ID: 22798075	2012
Cross talk between S-nitrosylation and S-glutathionylation in control of the Na,K-ATPase regulation in hypoxic heart. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 22982781	2012
The hypoxic placenta. High altitude medicine & biology\| PubMed ID: 22994517	2012
The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. Experimental physiology\| PubMed ID: 23180810	2013
Evidence of synergistic/additive effects of sildenafil and erythropoietin in enhancing survival and migration of hypoxic endothelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 23204066	2013
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood\| PubMed ID: 23264599	2013
Leh symposium 2012 and PVRI India annual symposium. High altitude medicine & biology\| PubMed ID: 23270450	2012
Fast-twitch glycolytic skeletal muscle is predisposed to age-induced impairments in mitochondrial function. The journals of gerontology. Series A, Biological sciences and medical sciences\| PubMed ID: 23371970	2013
Using plethysmography to determine erythropoietin's impact on neural control of ventilation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23456876	2013
Erythropoietin contributes to slow oxidative muscle fiber specification via PGC-1α and AMPK activation. The international journal of biochemistry & cell biology\| PubMed ID: 23523698	2013
Erythrocytosis: the HIF pathway in control. Blood\| PubMed ID: 23733342	2013
Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice. Hepatology (Baltimore, Md.)\| PubMed ID: 23744538	2013
Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers. Hepatology (Baltimore, Md.)\| PubMed ID: 23787477	2013
Neuropilin-1 modulates vascular endothelial growth factor-induced poly(ADP-ribose)-polymerase leading to reduced cerebrovascular apoptosis. Neurobiology of disease\| PubMed ID: 23816753	2013
Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development. International journal of cancer\| PubMed ID: 23913502	2014
N-methyl-D-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation. American journal of physiology. Cell physiology\| PubMed ID: 24048732	2013
Reduced insulin sensitivity as a marker for acute mountain sickness? High altitude medicine & biology\| PubMed ID: 24067185	2013
Restraint stress enhances arterial thrombosis in vivo--role of the sympathetic nervous system. Stress (Amsterdam, Netherlands)\| PubMed ID: 24215418	2014
Decreased stability of erythroblastic islands in integrin β3-deficient mice. Physiological reports\| PubMed ID: 24303107	2013
Hypoxia selectively disrupts brain microvascular endothelial tight junction complexes through a hypoxia-inducible factor-1 (HIF-1) dependent mechanism. Journal of cellular physiology\| PubMed ID: 24375098	2014
Presence of the Gpr179(nob5) allele in a C3H-derived transgenic mouse. Molecular vision\| PubMed ID: 24415894	2013
Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway. Journal of cardiothoracic surgery\| PubMed ID: 24885948	2014
Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 24970780	2014
Combination of erythropoietin and sildenafil can effectively attenuate hypoxia-induced pulmonary hypertension in mice. Pulmonary circulation\| PubMed ID: 25006406	2013
Red blood cells of sickle cell disease patients exhibit abnormally high abundance of N-methyl D-aspartate receptors mediating excessive calcium uptake. British journal of haematology\| PubMed ID: 25041184	2014
Mice over-expressing human erythropoietin indicate that erythropoietin enhances expression of its receptor via up-regulated Gata1 and Tal1. Haematologica\| PubMed ID: 25085352	2014
Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. British journal of haematology\| PubMed ID: 25283956	2015
Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 25519735	2015
Erythropoietin directly stimulates osteoclast precursors and induces bone loss. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 25630969	2015
The hypoxia-induced microRNA-130a controls pulmonary smooth muscle cell proliferation by directly targeting CDKN1A. The international journal of biochemistry & cell biology\| PubMed ID: 25681685	2015
Moderate hypothermia during ex vivo machine perfusion promotes recovery of hearts donated after cardiocirculatory death†. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 25740820	2016
The effects of short-term and long-term testosterone supplementation on blood viscosity and erythrocyte deformability in healthy adult mice. Endocrinology\| PubMed ID: 25774550	2015
Functional plasticity of the N-methyl-d-aspartate receptor in differentiating human erythroid precursor cells. American journal of physiology. Cell physiology\| PubMed ID: 25788577	2015
Featured Article: microRNA-125a in pulmonary hypertension: Regulator of a proliferative phenotype of endothelial cells. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 25854878	2015
Differential responses of blood-brain barrier associated cells to hypoxia and ischemia: a comparative study. Fluids and barriers of the CNS\| PubMed ID: 25879623	2015
PHYSIOLOGY. Regulation of breathing by CO₂ requires the proton-activated receptor GPR4 in retrotrapezoid nucleus neurons. Science (New York, N.Y.)\| PubMed ID: 26068853	2015
Adaptation of iron requirement to hypoxic conditions at high altitude. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 26183475	2015
Elevated hepcidin serum level in response to inflammatory and iron signals in exercising athletes is independent of moderate supplementation with vitamin C and E. Physiological reports\| PubMed ID: 26243212	2015
Neuronal erythropoietin overexpression protects mice against age-related hearing loss (presbycusis). Neurobiology of aging\| PubMed ID: 26364734	2015
Temporal Rac1 - HIF-1 crosstalk modulates hypoxic survival of aged neurons. Brain research\| PubMed ID: 27018294	2016
Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 27082941	2016
Comparing the impact of an acute exercise bout on plasma amino acid composition, intraerythrocytic Ca(2+) handling, and red cell function in athletes and untrained subjects. Cell calcium\| PubMed ID: 27292137	2016
Pregnancy at high altitude in the Andes leads to increased total vessel density in healthy newborns. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 27445300	2016
Cardiac N-methyl D-aspartate Receptors as a Pharmacological Target. Journal of cardiovascular pharmacology\| PubMed ID: 27525575	2016
Kinetic mRNA Profiling in a Rat Model of Left-Ventricular Hypertrophy Reveals Early Expression of Chemokines and Their Receptors. PloS one\| PubMed ID: 27525724	2016
Hypercapnic ventilatory response is decreased in a mouse model of excessive erythrocytosis. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 27605561	2016
Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice. Stem cell reports\| PubMed ID: 27618723	2016
Arginine-vasopressin marker copeptin is a sensitive plasma surrogate of hypoxic exposure. Hypoxia (Auckland, N.Z.)\| PubMed ID: 27774473	2014
Analysis of hypoxia-induced noncoding RNAs reveals metastasis-associated lung adenocarcinoma transcript 1 as an important regulator of vascular smooth muscle cell proliferation. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 28056547	2017
Protocol for a prospective, controlled, observational study to evaluate the influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease: the Altitude IBD Study. BMJ open\| PubMed ID: 28057654	2017
Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension. Basic research in cardiology\| PubMed ID: 28409279	2017
Erythropoietin enhances Kupffer cell number and activity in the challenged liver. Scientific reports\| PubMed ID: 28871174	2017
Biological aortic valve replacement: advantages and optimal indications of stentless compared to stented valve substitutes. A review. General thoracic and cardiovascular surgery\| PubMed ID: 29322433	2018