Haematopoietic Stem Cell Laboratory
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WTX is rarely mutated in acute myeloid leukemia.
Haematologica Jun, 2008 | Pubmed ID: 18460646
Haematopoietic stem cells.
The Journal of pathology Jul, 2002 | Pubmed ID: 12115860
Male cells in female recipients of hematopoietic-cell transplants.
The New England journal of medicine Jul, 2002 | Pubmed ID: 12125713
C1qRp defines a new human stem cell population with hematopoietic and hepatic potential.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2002 | Pubmed ID: 12140365
Solid-phase synthesis of tetrahydro-beta-carbolinehydantoins via the N-acyliminium Pictet-Spengler reaction and cyclative cleavage.
Journal of combinatorial chemistry Nov-Dec, 2002 | Pubmed ID: 12425597
Simultaneous lipidation of a characterized peptide mixture by chemoselective ligation.
Bioconjugate chemistry Mar-Apr, 2003 | Pubmed ID: 12643762
Expansion of human SCID-repopulating cells under hypoxic conditions.
The Journal of clinical investigation Jul, 2003 | Pubmed ID: 12840067
Solid-phase functionalization of peptides by an alpha-hydrazinoacetyl group.
The Journal of organic chemistry Sep, 2003 | Pubmed ID: 12946145
Multiparameter analysis of murine bone marrow side population cells.
Blood Apr, 2004 | Pubmed ID: 14644998
Hematopoietic stem cells.
Birth defects research. Part C, Embryo today : reviews Aug, 2003 | Pubmed ID: 14671775
In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions.
Journal of cell science Nov, 2004 | Pubmed ID: 15494370
Development of a human acute myeloid leukaemia screening panel and consequent identification of novel gene mutation in FLT3 and CCND3.
British journal of haematology Feb, 2005 | Pubmed ID: 15667533
Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples.
Stem cells (Dayton, Ohio) Jun-Jul, 2005 | Pubmed ID: 15917471
Stem cells of the alveolar epithelium.
Lancet (London, England) Jul 16-22, 2005 | Pubmed ID: 16023517
Normal and leukaemic stem cells.
British journal of haematology Aug, 2005 | Pubmed ID: 16098060
Comparison of HIV- and EIAV-based vectors on their efficiency in transducing murine and human hematopoietic repopulating cells.
Molecular therapy : the journal of the American Society of Gene Therapy Sep, 2005 | Pubmed ID: 16099415
Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia.
Blood Dec, 2005 | Pubmed ID: 16131573
Effect of glycoamphiphiles on the solubilization and dendritic cell uptake of a lipopeptide: a preliminary study.
Molecular pharmaceutics Sep-Oct, 2005 | Pubmed ID: 16196495
AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML.
Blood Feb, 2006 | Pubmed ID: 16234360
Telomerase vaccination has no detectable effect on SCID-repopulating and colony-forming activities in the bone marrow of cancer patients.
Experimental hematology Nov, 2005 | Pubmed ID: 16263411
In vivo formation of unstable heterokaryons after liver damage and hematopoietic stem cell/progenitor transplantation.
Stem cells (Dayton, Ohio) Apr, 2006 | Pubmed ID: 16282440
Leukemic stem cells show the way.
Folia histochemica et cytobiologica , 2005 | Pubmed ID: 16382881
Implications of the expression of myeloid markers on normal and leukemic stem cells.
Cell cycle (Georgetown, Tex.) Feb, 2006 | Pubmed ID: 16397415
Development of a quantitative real-time polymerase chain reaction method for monitoring CEBPA mutations in normal karyotype acute myeloid leukaemia.
British journal of haematology Apr, 2006 | Pubmed ID: 16512836
Out of the blue: a comparison of Hoechst side population (SP) analysis of murine bone marrow using 325, 363 and 407 nm excitation sources.
Journal of immunological methods Mar, 2006 | Pubmed ID: 16513131
Nonhematopoietic/endothelial SSEA-1+ cells define the most primitive progenitors in the adult murine bone marrow mesenchymal compartment.
Blood Feb, 2007 | Pubmed ID: 17003364
Use of a fluorescent polarization based high throughput assay to identify new calmodulin ligands.
Biochimica et biophysica acta Nov, 2006 | Pubmed ID: 17081635
A rapid and versatile method to label receptor ligands using "click" chemistry: Validation with the muscarinic M1 antagonist pirenzepine.
Bioconjugate chemistry Nov-Dec, 2006 | Pubmed ID: 17105244
Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging.
Stem cells (Dayton, Ohio) Apr, 2007 | Pubmed ID: 17158238
Convenient method to access new 4,4-dialkoxy- and 4,4-diaryloxy-diaza-s-indacene dyes: Synthesis and spectroscopic evaluation.
The Journal of organic chemistry Jan, 2007 | Pubmed ID: 17194109
Solid-phase preparation of a pilot library derived from the 2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-amine scaffold.
Journal of combinatorial chemistry May-Jun, 2007 | Pubmed ID: 17358083
Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung.
Stem cells (Dayton, Ohio) Jun, 2007 | Pubmed ID: 17363552
Murine leukemia following irradiation conditioning for transplantation of lentivirally-modified hematopoietic stem cells.
European journal of haematology Apr, 2007 | Pubmed ID: 17378892
The combined use of Hoechst efflux ability and aldehyde dehydrogenase activity to identify murine and human hematopoietic stem cells.
Experimental hematology Sep, 2007 | Pubmed ID: 17656008
Flexible and dynamic organization of bone marrow stromal compartment.
British journal of haematology Nov, 2007 | Pubmed ID: 17910627
Ageing within the hematopoietic stem cell compartment.
Mechanisms of ageing and development Jan-Feb, 2009 | Pubmed ID: 18502471
Solid-phase organic tagging resins for labeling biomolecules by 1,3-dipolar cycloaddition: application to the synthesis of a fluorescent non-peptidic vasopressin receptor ligand.
Chemistry (Weinheim an der Bergstrasse, Germany) , 2008 | Pubmed ID: 18512866
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.
Blood Aug, 2008 | Pubmed ID: 18523148
Small neutralizing molecules to inhibit actions of the chemokine CXCL12.
The Journal of biological chemistry Aug, 2008 | Pubmed ID: 18556651
Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Nov, 2008 | Pubmed ID: 18591546
Isolation, culture, and differentiation potential of mouse marrow stromal cells.
Current protocols in stem cell biology Oct, 2008 | Pubmed ID: 18972375
In vivo evaluation of leukemic stem cells through the xenotransplantation model.
Current protocols in stem cell biology Dec, 2008 | Pubmed ID: 19085977
Humanized mouse models to study the human haematopoietic stem cell compartment.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19110636
Humanized model to study leukemic stem cells.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19277589
AZD1152 rapidly and negatively affects the growth and survival of human acute myeloid leukemia cells in vitro and in vivo.
Cancer research May, 2009 | Pubmed ID: 19366807
Biased agonist pharmacochaperones of the AVP V2 receptor may treat congenital nephrogenic diabetes insipidus.
Journal of the American Society of Nephrology : JASN Oct, 2009 | Pubmed ID: 19729439
Circulating microparticles and procoagulant activity in elderly patients.
The journals of gerontology. Series A, Biological sciences and medical sciences Apr, 2010 | Pubmed ID: 19942591
Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosis.
PloS one Nov, 2009 | Pubmed ID: 19956603
Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology May, 2010 | Pubmed ID: 20040517
Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
Blood Mar, 2010 | Pubmed ID: 20053758
alpha5beta1 integrin antagonists reduce chemotherapy-induced premature senescence and facilitate apoptosis in human glioblastoma cells.
International journal of cancer. Journal international du cancer Sep, 2010 | Pubmed ID: 20099278
Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications.
Pharmacology & therapeutics Apr, 2010 | Pubmed ID: 20117133
Bone marrow mesenchymal stromal cells non-selectively protect chronic myeloid leukemia cells from imatinib-induced apoptosis via the CXCR4/CXCL12 axis.
Haematologica Jul, 2010 | Pubmed ID: 20179085
"Microenvironmental contaminations" induced by fluorescent lipophilic dyes used for noninvasive in vitro and in vivo cell tracking.
Blood Jul, 2010 | Pubmed ID: 20215639
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.
The Journal of experimental medicine Jun, 2010 | Pubmed ID: 20479117
An antagonistic pair of FT homologs mediates the control of flowering time in sugar beet.
Science (New York, N.Y.) Dec, 2010 | Pubmed ID: 21127254
Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter.
PloS one Nov, 2010 | Pubmed ID: 21152427
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells.
Cancer cell Dec, 2010 | Pubmed ID: 21156284
Heterogeneous sensitivity of human acute myeloid leukemia to β-catenin down-modulation.
Leukemia May, 2011 | Pubmed ID: 21339756
Prospective identification and isolation of murine bone marrow derived multipotent mesenchymal progenitor cells.
Best practice & research. Clinical haematology Mar, 2011 | Pubmed ID: 21396589
Age-related changes in human hematopoietic stem/progenitor cells.
Aging cell Jun, 2011 | Pubmed ID: 21418508
Involvement of the TGFβ pathway in the regulation of α5 β1 integrins by caveolin-1 in human glioblastoma.
International journal of cancer. Journal international du cancer Aug, 2012 | Pubmed ID: 21901744
Aerodynamically assisted bio-jetting of hematopoietic stem cells.
The Analyst Mar, 2012 | Pubmed ID: 22297267
Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors.
Journal of medicinal chemistry Mar, 2012 | Pubmed ID: 22329602
Proper desensitization of CXCR4 is required for lymphocyte development and peripheral compartmentalization in mice.
Blood Jun, 2012 | Pubmed ID: 22438253
DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues.
Blood Jun, 2012 | Pubmed ID: 22442345
Combinatorial aid for underprivileged scaffolds: solution and solid-phase strategies for a rapid and efficient access to novel aza-diketopiperazines (Aza-DKP).
ACS combinatorial science May, 2012 | Pubmed ID: 22458603
Human mesenchymal stromal cells senesce with exogenous OCT4.
Cytotherapy Oct, 2012 | Pubmed ID: 22746537
Engraftment defect of cytokine-cultured adult human mobilized CD34(+) cells is related to reduced adhesion to bone marrow niche elements.
British journal of haematology Sep, 2012 | Pubmed ID: 22816563
Embryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanisms.
Stem cells (Dayton, Ohio) Oct, 2012 | Pubmed ID: 22851508
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis.
European journal of immunology Dec, 2012 | Pubmed ID: 22936024
Selective fluorescent nonpeptidic antagonists for vasopressin V₂ GPCR: application to ligand screening and oligomerization assays.
Journal of medicinal chemistry Oct, 2012 | Pubmed ID: 22984902
Cancer stem cell definitions and terminology: the devil is in the details.
Nature reviews. Cancer 11, 2012 | Pubmed ID: 23051844
Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications.
Cancer research Feb, 2013 | Pubmed ID: 23345162
Targeting of acute myeloid leukaemia by cytokine-induced killer cells redirected with a novel CD123-specific chimeric antigen receptor.
British journal of haematology May, 2013 | Pubmed ID: 23432359
An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice.
The Journal of biological chemistry Apr, 2013 | Pubmed ID: 23449983
Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands.
Molecular pharmacology Jul, 2013 | Pubmed ID: 23604140
Multimodal imaging reveals structural and functional heterogeneity in different bone marrow compartments: functional implications on hematopoietic stem cells.
Blood Sep, 2013 | Pubmed ID: 23814020
Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2013 | Pubmed ID: 23901108
CD34(-) cells at the apex of the human hematopoietic stem cell hierarchy have distinctive cellular and molecular signatures.
Cell stem cell Aug, 2013 | Pubmed ID: 23910083
DNA methylation analysis of murine hematopoietic side population cells during aging.
Epigenetics Oct, 2013 | Pubmed ID: 23949429
Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche.
Journal of biomedical science Sep, 2013 | Pubmed ID: 24024707
HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress.
Cell stem cell Nov, 2013 | Pubmed ID: 24095676
A novel model of dormancy for bone metastatic breast cancer cells.
Cancer research Dec, 2013 | Pubmed ID: 24145351
Forgotten gems: human CD34(-) hematopoietic stem cells.
Cell cycle (Georgetown, Tex.) , 2014 | Pubmed ID: 24419157
Red fluorescent turn-on ligands for imaging and quantifying G protein-coupled receptors in living cells.
Chembiochem : a European journal of chemical biology Feb, 2014 | Pubmed ID: 24449564
A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: a new tool to decipher their chemoresistance and self-renewal mechanisms.
Stem cells translational medicine Apr, 2014 | Pubmed ID: 24493855
Structure-activity relationship studies toward the discovery of selective apelin receptor agonists.
Journal of medicinal chemistry Apr, 2014 | Pubmed ID: 24625069
Mesenchymal stem cell biodistribution, migration, and homing in vivo.
Stem cells international , 2014 | Pubmed ID: 24738002
Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo.
ACS medicinal chemistry letters Jan, 2012 | Pubmed ID: 24900366
Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition process.
Chemical communications (Cambridge, England) Sep, 2014 | Pubmed ID: 25019687
CD123 AML targeting by chimeric antigen receptors: A novel magic bullet for AML therapeutics?
Oncoimmunology , 2014 | Pubmed ID: 25083319
Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer.
ACS chemical biology Feb, 2015 | Pubmed ID: 25350273
Fluorogenic squaraine dimers with polarity-sensitive folding as bright far-red probes for background-free bioimaging.
Journal of the American Chemical Society Jan, 2015 | Pubmed ID: 25506627
Increasing cellular immunogenicity to peptide-based vaccine candidates using a fluorocarbon antigen delivery system.
Vaccine Feb, 2015 | Pubmed ID: 25573036
Selective nonpeptidic fluorescent ligands for oxytocin receptor: design, synthesis, and application to time-resolved FRET binding assay.
Journal of medicinal chemistry Mar, 2015 | Pubmed ID: 25642985
APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.
PloS one , 2015 | Pubmed ID: 25807502
Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo.
Blood Jun, 2015 | Pubmed ID: 25896651
Characteristics of human primary mantle cell lymphoma engraftment in NSG mice.
British journal of haematology Apr, 2016 | Pubmed ID: 26215849
New fluorescein precursors for live bacteria detection.
Analytical chemistry Sep, 2015 | Pubmed ID: 26260548
[Heroin makes asthma difficult and sometimes nearly fatal].
Presse medicale (Paris, France : 1983) Oct, 2015 | Pubmed ID: 26337357
A strategy to discover decoy chemokine ligands with an anti-inflammatory activity.
Scientific reports Oct, 2015 | Pubmed ID: 26442456
Different Motile Behaviors of Human Hematopoietic Stem versus Progenitor Cells at the Osteoblastic Niche.
Stem cell reports Nov, 2015 | Pubmed ID: 26455414
Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model.
PloS one , 2015 | Pubmed ID: 26465138
The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia.
Annals of hematology Jan, 2016 | Pubmed ID: 26499507
A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia.
British journal of haematology Feb, 2016 | Pubmed ID: 26597595
SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment.
Nature communications Dec, 2015 | Pubmed ID: 26643973
Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact.
Expert opinion on biological therapy , 2016 | Pubmed ID: 26679619
Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging.
Chemistry (Weinheim an der Bergstrasse, Germany) Jan, 2016 | Pubmed ID: 26682530
Frequency and Dynamics of Leukemia-Initiating Cells during Short-term Ex Vivo Culture Informs Outcomes in Acute Myeloid Leukemia Patients.
Cancer research 04, 2016 | Pubmed ID: 26960976
Perturbed hematopoiesis in mice lacking ATMIN.
Blood Oct, 2016 | Pubmed ID: 27581360
A step-economical multicomponent synthesis of 3D-shaped aza-diketopiperazines and their drug-like chemical space analysis.
Organic & biomolecular chemistry Sep, 2016 | Pubmed ID: 27722636
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.
Nature 10, 2016 | Pubmed ID: 27750279
Myelodysplastic syndrome can propagate from the multipotent progenitor compartment.
Haematologica Jan, 2017 | Pubmed ID: 27758823
Development of original metabolically stable apelin-17 analogs with diuretic and cardiovascular effects.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Feb, 2017 | Pubmed ID: 27815337
Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells.
Blood Feb, 2017 | Pubmed ID: 27899358
Versatile humanized niche model enables study of normal and malignant human hematopoiesis.
The Journal of clinical investigation Feb, 2017 | Pubmed ID: 28067666
Comparative Study of the Synthesis and Structural and Physicochemical Properties of Diketopiperazines vs Aza-diketopiperazines.
The Journal of organic chemistry Mar, 2017 | Pubmed ID: 28230990
A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor.
ChemMedChem Jun, 2017 | Pubmed ID: 28374567
Acute myeloid leukemia including favorable-risk group samples engraft in NSG mice: just be patient.
Haematologica May, 2017 | Pubmed ID: 28458252
Push-pull dioxaborine as fluorescent molecular rotor: far-red fluorogenic probe for ligand-receptor interactions.
Journal of materials chemistry. C, Materials for optical and electronic devices Apr, 2016 | Pubmed ID: 28491320
Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation.
Stem cell reports Jul, 2017 | Pubmed ID: 28648895
Dendritic Cell Lineage Potential in Human Early Hematopoietic Progenitors.
Cell reports Jul, 2017 | Pubmed ID: 28723558
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