Joanne Young

Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors.

Reciprocal relationship between methylation status and loss of heterozygosity at the p14(ARF) locus in Australian and South African hepatocellular carcinomas.

Evolution of colorectal cancer: change of pace and change of direction.

Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers.

Association of the SULT1A1 R213H polymorphism with colorectal cancer.

Emerging concepts in colorectal neoplasia.

Hypermethylation of HPP1 is associated with hMLH1 hypermethylation in gastric adenocarcinomas.

Correspondence re: P. Laiho et al., Low-level microsatellite instability in most colorectal carcinomas. Cancer Res., 62: 1166-1170, 2002.

Morphological and molecular heterogeneity within nonmicrosatellite instability-high colorectal cancer.

Aberrant methylation of the HPP1 gene in ulcerative colitis-associated colorectal carcinoma.

Mutation searching in colorectal cancer studies: experience with a denaturing high-pressure liquid chromatography system for exon-by-exon scanning of tumour suppressor genes.

Analysis of the transcription regulator, CNOT7, as a candidate chromosome 8 tumor suppressor gene in colorectal cancer.

The impact of microsatellite instability on the molecular phenotype of colorectal tumors.

Peutz-Jeghers syndrome: genetic screening.

Fas ligand and tumour counter-attack in colorectal cancer stratified according to microsatellite instability status.

Role of inherited defects of MYH in the development of sporadic colorectal cancer.

Identification of genes uniquely involved in frequent microsatellite instability colon carcinogenesis by expression profiling combined with epigenetic scanning.

Mapping of a candidate colorectal cancer tumor-suppressor gene to a 900-kilobase region on the short arm of chromosome 8.

Cadherin/catenin complex appears to be intact in hepatocellular carcinomas from Australia and South Africa.

Regulation of microtubule-dependent recycling at the trans-Golgi network by Rab6A and Rab6A'.

Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation.

Conversion analysis for mutation detection in MLH1 and MSH2 in patients with colorectal cancer.

Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer.

Type 1 protein secretion in bacteria, the ABC-transporter dependent pathway (review).

Use of molecular tumor characteristics to prioritize mismatch repair gene testing in early-onset colorectal cancer.

DNA methylation patterns in adenomas from FAP, multiple adenoma and sporadic colorectal carcinoma patients.

Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation.

The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b.

Low somatic K-ras mutation frequency in colorectal cancer diagnosed under the age of 45 years.

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer.

Hyperplastic polyposis syndrome: phenotypic presentations and the role of MBD4 and MYH.

Vaccinia-virus-induced cellular contractility facilitates the subcellular localization of the viral replication sites.

The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature.

SnoN expression is differently regulated in microsatellite unstable compared with microsatellite stable colorectal cancers.

High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy.

Stability of BAT26 in Lynch syndrome colorectal tumours.

Epigenetic stem cell signature in cancer.

Silencing of O6-methylguanine DNA methyltransferase in the absence of promoter hypermethylation in hepatocellular carcinomas from Australia and South Africa.

The MUC13 cell surface mucin is highly expressed by human colorectal carcinomas.

Microsatellite instability markers for identifying early-onset colorectal cancers caused by germ-line mutations in DNA mismatch repair genes.

Serrated pathway colorectal cancer in the population: genetic consideration.

Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study.

Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.

Hyperplastic polyposis in the New Zealand population: a condition associated with increased colorectal cancer risk and European ancestry.

Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients.

Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development.

Serrated neoplasia of the colorectum and cigarette smoking.

The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations.

Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype.

Lynch syndrome in women less than 50 years of age with endometrial cancer.

Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening.

Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis.

The association of tumor microsatellite instability phenotype with family history of colorectal cancer.

Classifying MLH1 and MSH2 variants using bioinformatic prediction, splicing assays, segregation, and tumor characteristics.

A perspective on bi-allelic MUTYH mutations in patients with hyperplastic polyposis syndrome.

Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability.

HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers.

Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.

Varying etiologies lead to different molecular changes in Australian and South African hepatocellular carcinomas.

Screening for microsatellite instability identifies frequent 3'-untranslated region mutation of the RB1-inducible coiled-coil 1 gene in colon tumors.

Parent of origin effects on age at colorectal cancer diagnosis.

Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.

Risks of Lynch syndrome cancers for MSH6 mutation carriers.

RAB6C is a retrogene that encodes a centrosomal protein involved in cell cycle progression.

Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study.

Lynch syndrome-associated breast cancers: clinicopathologic characteristics of a case series from the colon cancer family registry.

Lessons from Lynch syndrome: a tumor biology-based approach to familial colorectal cancer.

Risk of endometrial cancer for women diagnosed with HNPCC-related colorectal carcinoma.

Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22.

A day at a time: caregiving on the edge in advanced COPD.

Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics.

Risk factors: Hyperplastic polyposis syndrome and risk of colorectal cancer.

Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome).

Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.

Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery.

Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients.

Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome.

Mutation deep within an intron of MSH2 causes Lynch syndrome.

Body mass index in early adulthood and endometrial cancer risk for mismatch repair gene mutation carriers.

Report of Endometrial Cancer in Australian BRCA1 and BRCA2 mutation-positive Families.

Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry.

Determining the frequency of de novo germline mutations in DNA mismatch repair genes.

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.

Serrated polyposis: an enigmatic model of colorectal cancer predisposition.

Hyperplastic polyp of the duodenum: a report of 9 cases with immunohistochemical and molecular findings.

Molecular change that distinguishes traditional serrated adenomas from sessile serrated adenomas.

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13.

Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry.

KRAS mutations in ovarian low-grade endometrioid adenocarcinoma: association with concurrent endometriosis.

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry.

Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study.