Department of Chemical and Biomolecular Engineering,
Center for Lung Biology,
Department of Pharmacology
Dr. Silas Leavesley is a professor of Chemical and Biomolecular Engineering at the University of South Alabama Dr. Leavesley also holds appointments in the Department of Pharmacology and the Center for Lung Biology. Dr. Leavesley’s research focuses on the design and implementation of hyperspectral imaging technology for research, preclinical and clinical diagnostics – including microscopy and endoscopy platforms.
Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue.
Journal of biophotonics Jan, 2012 | Pubmed ID: 21987373
Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells.
American journal of physiology. Cell physiology Mar, 2012 | Pubmed ID: 22116306
Hyperspectral imaging of FRET-based cGMP probes.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23709027
An approach for characterizing and comparing hyperspectral microscopy systems.
Sensors (Basel, Switzerland) Jul, 2013 | Pubmed ID: 23877125
Assessing FRET using spectral techniques.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Oct, 2013 | Pubmed ID: 23929684
Thin-film tunable filters for hyperspectral fluorescence microscopy.
Journal of biomedical optics Jan, 2014 | Pubmed ID: 24077519
Can we decipher the information content contained within cyclic nucleotide signals?
The Journal of general physiology Jan, 2014 | Pubmed ID: 24378904
Excitation-scanning hyperspectral imaging microscope.
Journal of biomedical optics Apr, 2014 | Pubmed ID: 24727909
A device for performing automated balloon catheter inflation ischemia studies.
PloS one , 2014 | Pubmed ID: 24769885
FRET: signals hidden within the noise.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Nov, 2014 | Pubmed ID: 25241962
Automated image analysis of FRET signals for subcellular cAMP quantification.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25783877
Channel-based reporters for cAMP detection.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25783878
Estimating the magnitude of near-membrane PDE4 activity in living cells.
American journal of physiology. Cell physiology Sep, 2015 | Pubmed ID: 26201952
Overcoming limitations of FRET measurements.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Apr, 2016 | Pubmed ID: 27101317
Hyperspectral imaging fluorescence excitation scanning for colon cancer detection.
Journal of biomedical optics 10, 2016 | Pubmed ID: 27792808
infection liberates transmissible, cytotoxic prion amyloids.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 07, 2017 | Pubmed ID: 28314768
A theoretical-experimental methodology for assessing the sensitivity of biomedical spectral imaging platforms, assays, and analysis methods.
Journal of biophotonics Jan, 2018 | Pubmed ID: 28485093
Human ASIC1a mediates stronger acid-induced responses as compared with mouse ASIC1a.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2018 | Pubmed ID: 29447005
Feasibility of using thermal response to K band millimeter wave heating to assess skin blood flow.
Physiological measurement Apr, 2018 | Pubmed ID: 29513271
Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 10, 2018 | Pubmed ID: 30176184
Nosocomial Pneumonia Elicits an Endothelial Proteinopathy: Evidence for a Source of Neurotoxic Amyloids in Critically Ill Patients.
American journal of respiratory and critical care medicine Oct, 2018 | Pubmed ID: 30280916
Tycho Brahe's way to precision.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 10, 2018 | Pubmed ID: 30347520
Identifying molecular contributors to autofluorescence of neoplastic and normal colon sections using excitation-scanning hyperspectral imaging.
Journal of biomedical optics 12, 2018 | Pubmed ID: 30592190
Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Jun, 2019 | Pubmed ID: 31207046
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