Cameron S. Metcalf

Department of Pharmacology and Toxicology, University of Utah

Research Area

MedicineNeuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2011
Publication title	2022

Other Publications

Article	Year
Increased dietary sodium enhances activation of neurons in the medullary cardiovascular pathway during acute sodium loading in the rat. Autonomic neuroscience : basic & clinical\| PubMed ID: 15620568	2005
Increased dietary sodium alters Fos expression in the lamina terminalis during intravenous angiotensin II infusion. Experimental neurology\| PubMed ID: 17214984	2007
Differential regional effects of methamphetamine on dopamine transport. European journal of pharmacology\| PubMed ID: 18599036	2008
Status epilepticus produces chronic alterations in cardiac sympathovagal balance. Epilepsia\| PubMed ID: 18727681	2009
Status epilepticus induces cardiac myofilament damage and increased susceptibility to arrhythmias in rats. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 19820194	2009
Autonomic and cellular mechanisms mediating detrimental cardiac effects of status epilepticus. Epilepsy research\| PubMed ID: 20650612	2010
Incorporation of monodisperse oligoethyleneglycol amino acids into anticonvulsant analogues of galanin and neuropeptide y provides peripherally acting analgesics. Molecular pharmaceutics\| PubMed ID: 23259957	2013
Analgesic properties of a peripherally acting and GalR2 receptor-preferring galanin analog in inflammatory, neuropathic, and acute pain models. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 25347995	2015
Preclinical evaluation of intravenous NAX 810-2, a novel GalR2-preferring analog, for anticonvulsant efficacy and pharmacokinetics. Epilepsia\| PubMed ID: 28098336	2017
Efficacy of mGlu -positive allosteric modulators alone and in combination with levetiracetam in the mouse 6 Hz model of psychomotor seizures. Epilepsia\| PubMed ID: 28166368	2017
Preclinical Analgesic and Safety Evaluation of the GalR2-preferring Analog, NAX 810-2. Neurochemical research\| PubMed ID: 28382595	2017
Development and pharmacologic characterization of the rat 6 Hz model of partial seizures. Epilepsia\| PubMed ID: 28449218	2017
Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP). Neurochemical research\| PubMed ID: 28478594	2017
Novel Targets for Developing Antiseizure and, Potentially, Antiepileptogenic Drugs. Epilepsy currents\| PubMed ID: 29225544	2017
Potent and selective pharmacodynamic synergy between the metabotropic glutamate receptor subtype 2-positive allosteric modulator JNJ-46356479 and levetiracetam in the mouse 6-Hz (44-mA) mode... Epilepsia\| PubMed ID: 29360159	2018
Recurrent epileptiform discharges in the medial entorhinal cortex of kainate-treated rats are differentially sensitive to antiseizure drugs. Epilepsia\| PubMed ID: 30328622	2018
Music-Enhanced Analgesia and Antiseizure Activities in Animal Models of Pain and Epilepsy: Toward Preclinical Studies Supporting Development of Digital Therapeutics and Their Combinations Wi... Frontiers in neurology\| PubMed ID: 30972009	2019
Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine-resistant amygdala kindling model. Epilepsia open\| PubMed ID: 31440726	2019
The current approach of the Epilepsy Therapy Screening Program contract site for identifying improved therapies for the treatment of pharmacoresistant seizures in epilepsy. Neuropharmacology\| PubMed ID: 31790717	2020
Discovery of the First Vitamin K Analogue as a Potential Treatment of Pharmacoresistant Seizures. Journal of medicinal chemistry\| PubMed ID: 32390424	2020
Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats. Epilepsia\| PubMed ID: 32420627	2020
Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model. International journal of pharmaceutics\| PubMed ID: 32739385	2020
Accurate detection of spontaneous seizures using a generalized linear model with external validation. Epilepsia\| PubMed ID: 32761902	2020
Preventing neuronal edema increases network excitability after traumatic brain injury. The Journal of clinical investigation\| PubMed ID: 33044227	2020
Cannabidiolic acid exhibits entourage-like improvements of anticonvulsant activity in an acute rat model of seizures. Epilepsy research\| PubMed ID: 33310415	2021
Response: Usefulness of the post-kainate spontaneous recurrent seizure model for screening for antiseizure and for neuroprotective effects. Epilepsia\| PubMed ID: 33778946	2021
Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program. Epilepsia\| PubMed ID: 34002394	2021
Screening of prototype antiseizure and anti-inflammatory compounds in the Theiler's murine encephalomyelitis virus model of epilepsy. Epilepsia open\| PubMed ID: 34668659	2022
Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs. Experimental neurology\| PubMed ID: 34922908	2022
Anticonvulsive properties of soticlestat, a novel cholesterol 24-hydroxylase inhibitor. Epilepsia\| PubMed ID: 35316533	2022
Precision medicine for genetic epilepsy on the horizon: recent advances, present challenges and suggestions for continued progress. Epilepsia\| PubMed ID: 35716052	2022