Paul Hofman

Laboratory of Clinical and Experimental Pathology, Université Côte d’Azur

Affiliated withUniversité Côte d’Azur Université Côte d’Azur, CHU de Nice Université Côte d'Azur, Hôpital Pasteur, CHU de Nice

Research Area

Cancer ResearchBiology

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2018
Publication title	2023

Other Publications

Article	Year
KRAS Mutations in Lung Adenocarcinoma: Molecular and Epidemiological Characteristics, Methods for Detection, and Therapeutic Strategy Perspectives. Current molecular medicine\| PubMed ID: 25941815	2015
Reply to the letter to the editor 'ALK FISH rearranged and amplified tumor with negative immunohistochemistry: a rare and challenging case concerning ALK status screening in lung cancer' by ... Annals of oncology : official journal of the European Society for Medical Oncology\| PubMed ID: 25957328	2015
Sense and nonsense in the process of accreditation of a pathology laboratory. Virchows Archiv : an international journal of pathology\| PubMed ID: 26334197	2016
Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic str... Annals of oncology : official journal of the European Society for Medical Oncology\| PubMed ID: 26483045	2016
[Search for circulating tumor cells: Seriously, a real cancer screening tool?]. Journal des maladies vasculaires\| PubMed ID: 26526763	2015
Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patients. Virchows Archiv : an international journal of pathology\| PubMed ID: 26915032	2016
[Issues and current limits for immunohistochemical assessment of PD-L1 status in bronchial biopsies]. Bulletin du cancer\| PubMed ID: 26920041	2016
Pathologists and liquid biopsies: to be or not to be? Virchows Archiv : an international journal of pathology\| PubMed ID: 27553354	2016
Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition. Nucleic acids research\| PubMed ID: 27994032	2017
Fibronectin-guided migration of carcinoma collectives. Nature communications\| PubMed ID: 28102238	2017
[PD1/PD-L1 immunohistochemistry in thoracic oncology: Where are we?] Annales de pathologie\| PubMed ID: 28159404	2017
Pathology of infectious diseases: what does the future hold? Virchows Archiv : an international journal of pathology\| PubMed ID: 28188440	2017
Expression of MET in circulating tumor cells correlates with expression in tumor tissue from advanced-stage lung cancer patients. Oncotarget\| PubMed ID: 28212540	2017
Annales de pathologie\| PubMed ID: 28778623	2017
Use of the 22C3 anti-PD-L1 antibody to determine PD-L1 expression in multiple automated immunohistochemistry platforms. PloS one\| PubMed ID: 28797130	2017
ALK Status Assessment with Liquid Biopsies of Lung Cancer Patients. Cancers\| PubMed ID: 28805673	2017
ALK in Non-Small Cell Lung Cancer (NSCLC) Pathobiology, Epidemiology, Detection from Tumor Tissue and Algorithm Diagnosis in a Daily Practice. Cancers\| PubMed ID: 28805682	2017
MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma. Oncotarget\| PubMed ID: 28915663	2017
Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer. Oncoimmunology\| PubMed ID: 28932641	2017
Liquid Biopsy and Therapeutic Targets: Present and Future Issues in Thoracic Oncology. Cancers\| PubMed ID: 29125548	2017
Atezolizumab in advanced non-small cell lung cancer. Journal of thoracic disease\| PubMed ID: 29268352	2017
Circulating tumour cells as a potential screening tool for lung cancer (the AIR study): protocol of a prospective multicentre cohort study in France. BMJ open\| PubMed ID: 29282271	2017
Reproducibility of PD-L1 assessment in non-small cell lung cancer-know your limits but never stop trying to exceed them. Translational lung cancer research\| PubMed ID: 29299411	2017
Use of circulating tumor cells in prospective clinical trials for NSCLC patients - standardization of the pre-analytical conditions. Clinical chemistry and laboratory medicine\| PubMed ID: 29397019	2018
Any Place for Immunohistochemistry within the Predictive Biomarkers of Treatment in Lung Cancer Patients? Cancers\| PubMed ID: 29534030	2018
Use of the Ion PGM and the GeneReader NGS Systems in Daily Routine Practice for Advanced Lung Adenocarcinoma Patients: A Practical Point of View Reporting a Comparative Study and Assessment ... Cancers\| PubMed ID: 29561830	2018
Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition. Nucleic acids research\| PubMed ID: 29562367	2018
E2F1 inhibition mediates cell death of metastatic melanoma. Cell death & disease\| PubMed ID: 29743521	2018
Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 29858030	2018
Ensuring the Safety and Security of Frozen Lung Cancer Tissue Collections through the Encapsulation of Dried DNA. Cancers\| PubMed ID: 29891792	2018
Establishing a Dedicated Lung Cancer Biobank at the University Center Hospital of Nice (France). Why and How? Cancers\| PubMed ID: 29966305	2018
Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma. Cancers\| PubMed ID: 30216999	2018
Lung Cancer Screening, Towards a Multidimensional Approach: Why and How? Cancers\| PubMed ID: 30759893	2019
[The age of artificial intelligence in lung cancer pathology: Between hope, gloom and perspectives]. Annales de pathologie\| PubMed ID: 30772062	2019
[Tumor banks and complex data management: Current and future challenges]. Annales de pathologie\| PubMed ID: 30819623	2019
[Pseudotumor lesions induced by infectious agents. Introduction]. Annales de pathologie\| PubMed ID: 31003708	2019
Liquid biopsy in the era of immuno-oncology: is it ready for prime-time use for cancer patients? Annals of oncology : official journal of the European Society for Medical Oncology\| PubMed ID: 31228184	2019
[Pseudo-tumor lesions induced by infectious agents. Case no. 7]. Annales de pathologie\| PubMed ID: 31255413	2019
[Pseudo-tumor lesions induced by infectious agents. Case no. 8]. Annales de pathologie\| PubMed ID: 31255414	2019
Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment. Cells\| PubMed ID: 31337010	2019
In-house Implementation of Tumor Mutational Burden Testing to Predict Durable Clinical Benefit in Non-small Cell Lung Cancer and Melanoma Patients. Cancers\| PubMed ID: 31470674	2019
EGFR Mutation Analysis in Non-small Cell Lung Carcinoma from Tissue Samples Using the Fully Automated Idylla™ qPCR System. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 31482454	2019
Critical Assessment in Routine Clinical Practice of Liquid Biopsy for EGFR Status Testing in Non-Small-Cell Lung Cancer: A Single-Laboratory Experience (LPCE, Nice, France). Clinical lung cancer\| PubMed ID: 31519454	2020
Prospective evaluation of NGS-based liquid biopsy in untreated late stage non-squamous lung carcinoma in a single institution. Journal of translational medicine\| PubMed ID: 32066459	2020
Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry. Nature medicine\| PubMed ID: 32382152	2020
Real-world assessment of the BRAF status in non-squamous cell lung carcinoma using VE1 immunohistochemistry: A single laboratory experience (LPCE, Nice, France). Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 32408133	2020
Comparison of Three Sequencing Panels Used for the Assessment of Tumor Mutational Burden in NSCLC Reveals Low Comparability. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 32450274	2020
Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype? Autophagy\| PubMed ID: 32521191	2020
Using Genetics To Dissect SARS-CoV-2 Infection. Trends in genetics : TIG\| PubMed ID: 33309104	2021
Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future. ESMO open\| PubMed ID: 33399086	2021
[Histopathological features due to the SARS-CoV-2]. Annales de pathologie\| PubMed ID: 33446414	2021
Prospective Multicenter Validation of the Detection of ALK Rearrangements of Circulating Tumor Cells for Noninvasive Longitudinal Management of Patients With Advanced NSCLC. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 33545389	2021
The Carcinogen Cadmium Activates Lysine 63 (K63)-Linked Ubiquitin-Dependent Signaling and Inhibits Selective Autophagy. Cancers\| PubMed ID: 34065348	2021
A rapid near-patient RT-PCR test for suspected COVID-19: a study of the diagnostic accuracy. Annals of translational medicine\| PubMed ID: 34350236	2021
Salivary detection of COVID-19: clinical performance of oral sponge sampling for SARS-CoV-2 testing. ERJ open research\| PubMed ID: 34877351	2021
Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis. Cancer discovery\| PubMed ID: 34930787	2022
Analytical validation of automated multiplex chromogenic immunohistochemistry for diagnostic and predictive purpose in non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 35134710	2022
Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases. Autophagy\| PubMed ID: 35383530	2022
Expression of NOTCH1, NOTCH4, HLA-DMA and HLA-DRA is synergistically associated with T cell exclusion, immune checkpoint blockade efficacy and recurrence risk in ER-negative breast cancer. Cellular oncology (Dordrecht)\| PubMed ID: 35543859	2022
Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 35550950	2022
Host genetic variability and determinants of severe COVID-19. Trends in genetics : TIG\| PubMed ID: 36379742	2023
Lack of correlation between MET and PD-L1 expression in non-small cell lung cancer revealed by comparative study of matched biopsies and surgical resection samples. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 37150140	2023
The significance of co-mutations in EGFR-mutated non-small cell lung cancer: Optimizing the efficacy of targeted therapies? Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 37244040	2023
Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion. Cell stem cell\| PubMed ID: 37267915	2023
Quantitative multiplexed imaging technologies for single-cell analysis to assess predictive markers for immunotherapy in thoracic immuno-oncology: promises and challenges. British journal of cancer\| PubMed ID: 37391504	2023
Matched tissue and liquid biopsies for advanced non-small cell lung cancer patients A potentially indispensable complementary approach. Translational oncology\| PubMed ID: 37413719	2023
Should evidence of an autolysosomal de-acidification defect in Alzheimer and Parkinson diseases call for caution in prescribing chronic PPI and DMARD? Autophagy\| PubMed ID: 37482676	2023
The Need to Set up a Biobank Dedicated to Lymphoid Malignancies: Experience of a Single Center (Laboratory of Clinical and Experimental Pathology, University Côte d'Azur, Nice, France). Journal of personalized medicine\| PubMed ID: 37511690	2023