Kai Zhu

Department of Cardiac Surgery, Fudan University

Affiliated withFudan University Shanghai Institute of Cardiovascular Disease Shanghai Institute of Cardiovascular Diseases

Research Area

MedicineBioengineering

Biography

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JoVE Journal Publications

Article Total : 3	Year
Publication title	2018
Publication title	2020
Publication title	2022

Other Publications

Article	Year
Combination of IGF‑1 gene manipulation and 5‑AZA treatment promotes differentiation of mesenchymal stem cells into cardiomyocyte‑like cells. Molecular medicine reports\| PubMed ID: 25351395	2015
[Value of preoperative barium contrast examination for the diagnosis and operative planning in gastric cancer]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery\| PubMed ID: 20422482	2010
Aqueous supercapacitors of high energy density based on MoO3 nanoplates as anode material. Chemical communications (Cambridge, England)\| PubMed ID: 21829794	2011
Novel hyperbranched polyamidoamine nanoparticles for transfecting skeletal myoblasts with vascular endothelial growth factor gene for cardiac repair. Journal of materials science. Materials in medicine\| PubMed ID: 21870080	2011
Metadherin promotes hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 21976539	2011
IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma. Molecular cancer\| PubMed ID: 22171994	2011
Novel hyperbranched polyamidoamine nanoparticle based gene delivery: transfection, cytotoxicity and in vitro evaluation. International journal of pharmaceutics\| PubMed ID: 22209826	2012
Novel vascular endothelial growth factor gene delivery system-manipulated mesenchymal stem cells repair infarcted myocardium. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 22728704	2012
High expression of Dickkopf-related protein 1 is related to lymphatic metastasis and indicates poor prognosis in intrahepatic cholangiocarcinoma patients after surgery. Cancer\| PubMed ID: 23132676	2013
A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses. PloS one\| PubMed ID: 23251663	2012
LiMn2O4 nanotube as cathode material of second-level charge capability for aqueous rechargeable batteries. Nano letters\| PubMed ID: 23537381	2013
Transplantation of novel vascular endothelial growth factor gene delivery system manipulated skeletal myoblasts promote myocardial repair. International journal of cardiology\| PubMed ID: 23578891	2013
Open triple-branched stent graft applied to patient of acute type A aortic dissection with aberrant right subclavian artery. Journal of cardiothoracic surgery\| PubMed ID: 23587108	2013
MiR-146a enhances angiogenic activity of endothelial cells in hepatocellular carcinoma by promoting PDGFRA expression. Carcinogenesis\| PubMed ID: 23671131	2013
Biomarkers for hepatocellular carcinoma: progression in early diagnosis, prognosis, and personalized therapy. Biomarker research\| PubMed ID: 24252133	2013
The cytokine and chemokine profiles in patients with hand, foot and mouth disease of different severities in Shanghai, China, 2010. PLoS neglected tropical diseases\| PubMed ID: 24367714	2013
Adenoviral delivery of recombinant hepatitis B virus expressing foreign antigenic epitopes for immunotherapy of persistent viral infection. Journal of virology\| PubMed ID: 24371056	2014
Aortic reoperation in a patient with Loeys-Dietz syndrome. Chinese medical journal\| PubMed ID: 24931266	2014
Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways. The Journal of pathology\| PubMed ID: 24962955	2014
MiR-302c inhibits tumor growth of hepatocellular carcinoma by suppressing the endothelial-mesenchymal transition of endothelial cells. Scientific reports\| PubMed ID: 25027009	2014
SCM-198 inhibits microglial overactivation and attenuates Aβ(1-40)-induced cognitive impairments in rats via JNK and NF-кB pathways. Journal of neuroinflammation\| PubMed ID: 25134526	2014
Nanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair. International journal of nanomedicine\| PubMed ID: 25429216	2014
Enhanced infarct myocardium repair mediated by thermosensitive copolymer hydrogel-based stem cell transplantation. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 25432986	2015
Reprogramming fibroblasts to pluripotency using arginine-terminated polyamidoamine nanoparticles based non-viral gene delivery system. International journal of nanomedicine\| PubMed ID: 25540584	2014
Palliative stent graft placement combined with subsequent open surgery for retrograde ascending dissection intra-thoracic endovascular aortic repair. Journal of thoracic disease\| PubMed ID: 25590002	2014
Fibrin patch-based insulin-like growth factor-1 gene-modified stem cell transplantation repairs ischemic myocardium. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 25767192	2015
Off-pump Skeletonized Versus Pedicled Left Internal Mammary Artery Grafting: Mid-term Results. Journal of cardiac surgery\| PubMed ID: 25873143	2015
The novel analogue of hirsutine as an anti-hypertension and vasodilatary agent both in vitro and in vivo. PloS one\| PubMed ID: 25909998	2015
Intramyocardial Autologous Bone Marrow-derived Stem Cells Injection for Ischemic Heart Disease Ineligible for Revascularization: A Systematic Review and Meta-analysis. Archives of medical research\| PubMed ID: 26070842	2015
Mitogen-activated protein kinase kinase kinase 4 deficiency in intrahepatic cholangiocarcinoma leads to invasive growth and epithelial-mesenchymal transition. Hepatology (Baltimore, Md.)\| PubMed ID: 26340507	2015
Nanoparticle-enhanced generation of gene-transfected mesenchymal stem cells for in vivo cardiac repair. Biomaterials\| PubMed ID: 26461114	2016
Severe aortic regurgitation and partial anomalous pulmonary venous connection in a Turner syndrome patient. Journal of thoracic disease\| PubMed ID: 26716053	2015
Tumour-suppressive role of PTPN13 in hepatocellular carcinoma and its clinical significance. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 26801674	2016
Nanoparticles-Assisted Stem Cell Therapy for Ischemic Heart Disease. Stem cells international\| PubMed ID: 26839552	2016
Direct 3D bioprinting of perfusable vascular constructs using a blend bioink. Biomaterials\| PubMed ID: 27552316	2016
Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip. Biomaterials\| PubMed ID: 27710832	2016
Developing miRNA therapeutics for cardiac repair in ischemic heart disease. Journal of thoracic disease\| PubMed ID: 27747027	2016
Rapid Continuous Multimaterial Extrusion Bioprinting. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 27859710	2017
Investigation of silk fibroin nanoparticle-decorated poly(l-lactic acid) composite scaffolds for osteoblast growth and differentiation. International journal of nanomedicine\| PubMed ID: 28331312	2017
Generation of an induced pluripotent stem cell line from a Loeys-Dietz syndrome patient with transforming growth factor-beta receptor-2 gene mutation. Stem cell research\| PubMed ID: 28395736	2017
Transcatheter aortic valve replacement in patients with high aortic anguation. Journal of thoracic disease\| PubMed ID: 28616338	2017
Contemporary In-Hospital and Long-Term Outcomes of Surgical Management for Fungal Endocarditis. International heart journal\| PubMed ID: 28690300	2017
Three-dimensional printing guided precise surgery for right-sided aortic arch associated with Kommerell's diverticulum. Journal of thoracic disease\| PubMed ID: 28740679	2017
Prostate-derived ETS factor improves prognosis and represses proliferation and invasion in hepatocellular carcinoma. Oncotarget\| PubMed ID: 28881746	2017
Blood-Vessel-on-a-Chip Platforms for Evaluating Nanoparticle Drug Delivery Systems. Current drug metabolism\| PubMed ID: 28952434	2018
Annuloplasty band implantation in adults with partial atrioventricular septal defect: a propensity-matched study. Interactive cardiovascular and thoracic surgery\| PubMed ID: 29069357	2018
Autologous Bone Marrow-Derived Stem Cells for Treating Diabetic Neuropathy in Metabolic Syndrome. BioMed research international\| PubMed ID: 29098161	2017
Should sinus of Valsalva be preserved in patients with bicuspid aortic valve and aortic dilation? Journal of thoracic disease\| PubMed ID: 29221290	2017
3D printing technique for guiding complicated cardiovascular surgery. Journal of thoracic disease\| PubMed ID: 29266100	2017
Molecular targets in aortic aneurysm for establishing novel management paradigms. Journal of thoracic disease\| PubMed ID: 29268541	2017
Patient-specific three-dimensional printing for Kommerell's diverticulum. International journal of cardiology\| PubMed ID: 29290421	2018
Smad1 promotes colorectal cancer cell migration through Ajuba transactivation. Oncotarget\| PubMed ID: 29299158	2017
Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma. Gastroenterology research and practice\| PubMed ID: 29333154	2017
Surgical and early outcomes for Type A aortic dissection with preoperative renal dysfunction stratified by estimated glomerular filtration rate. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery\| PubMed ID: 29672685	2018
Benefits of Early Surgery on Clinical Outcomes After Degenerative Mitral Valve Repair. The Annals of thoracic surgery\| PubMed ID: 29883645	2018
A General Strategy for Extrusion Bioprinting of Bio-Macromolecular Bioinks through Alginate-Templated Dual-Stage Crosslinking. Macromolecular bioscience\| PubMed ID: 29943499	2018
Bicuspid aortic valve with critical coarctation of the aorta: single- or two-stage operation? Journal of thoracic disease\| PubMed ID: 30174883	2018
Curved section modeling-based three-dimensional printing for guiding septal myectomy. Journal of thoracic disease\| PubMed ID: 30174927	2018
Gold Nanocomposite Bioink for Printing 3D Cardiac Constructs. Advanced functional materials\| PubMed ID: 30319321	2017
Sensor-free and Sensor-based Heart-on-a-chip Platform: A Review of Design and Applications. Current pharmaceutical design\| PubMed ID: 30734671	2018
EGR1-induced upregulation of lncRNA FOXD2-AS1 promotes the progression of hepatocellular carcinoma via epigenetically silencing DKK1 and activating Wnt/β-catenin signaling pathway. Cancer biology & therapy\| PubMed ID: 30929558	2019
Organ-on-A-Chip for Drug Screening and Personalized Medicine. Current pharmaceutical design\| PubMed ID: 31012397	2018
Highly Porous Microcarriers for Minimally Invasive In Situ Skeletal Muscle Cell Delivery. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 31066236	2019
Impacts of incomplete revascularization following off-pump coronary artery bypass grafting on clinical outcomes of patients with triple-vessel lesions: insights from a single-center study of... Journal of thoracic disease\| PubMed ID: 31179074	2019
SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycin. Apoptosis : an international journal on programmed cell death\| PubMed ID: 31227933	2019
Hydrogel Bioink with Multilayered Interfaces Improves Dispersibility of Encapsulated Cells in Extrusion Bioprinting. ACS applied materials & interfaces\| PubMed ID: 31378063	2019
Correction to: SPECT/CT imaging of apoptosis in aortic aneurysm with radiolabeled duramycin. Apoptosis : an international journal on programmed cell death\| PubMed ID: 31422488	2019
Metadherin-PRMT5 complex enhances the metastasis of hepatocellular carcinoma through the WNT-β-catenin signaling pathway. Carcinogenesis\| PubMed ID: 31498866	2020
Plasma hsa_circ_0027089 is a diagnostic biomarker for hepatitis B virus-related hepatocellular carcinoma. Carcinogenesis\| PubMed ID: 31535687	2019
Analysis of sternal healing after median sternotomy in low risk patients at midterm follow-up: retrospective cohort study from two centres. Journal of cardiothoracic surgery\| PubMed ID: 31711516	2019
TGM3 promotes epithelial-mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver\| PubMed ID: 31822388	2019
Bioprinting a 3D vascular construct for engineering a vessel-on-a-chip. Biomedical microdevices\| PubMed ID: 31875940	2019
Recurrence After Curative Resection of Hepatitis B Virus-Related Hepatocellular Carcinoma: Diagnostic Algorithms on Gadoxetic Acid-Enhanced Magnetic Resonance Imaging. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society\| PubMed ID: 31901208	2020
Complement activation in the arteries of patients with severe atherosclerosis. International journal of clinical and experimental pathology\| PubMed ID: 31938082	2018
A radiomics-based biomarker for cytokeratin 19 status of hepatocellular carcinoma with gadoxetic acid-enhanced MRI. European radiology\| PubMed ID: 32002645	2020
Mesoporous silica nanoparticles for glutathione-triggered long-range and stable release of hydrogen sulfide. Journal of materials chemistry. B\| PubMed ID: 32262789	2015
DCK is a promising prognostic biomarker and correlated with immune infiltrates in hepatocellular carcinoma. World journal of surgical oncology\| PubMed ID: 32690026	2020
Outcomes of emergency or urgent mitral valve repair in patients with papillary muscle rupture and active infective endocarditis. Asian cardiovascular & thoracic annals\| PubMed ID: 32938206	2020
Mitral valve repair for degenerative mitral regurgitation in patients with left ventricular systolic dysfunction: early and mid-term outcomes. Journal of cardiothoracic surgery\| PubMed ID: 33004041	2020
Toward a neurospheroid niche model: optimizing embedded 3D bioprinting for fabrication of neurospheroid brain-like co-culture constructs. Biofabrication\| PubMed ID: 33059333	2020
Pulmonary valve replacement in primary repair of tetralogy of Fallot in adult patients. Journal of thoracic disease\| PubMed ID: 33145056	2020
Modeling Endothelialized Hepatic Tumor Microtissues for Drug Screening. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 33173735	2020
Modeling aortic diseases using induced pluripotent stem cells. Stem cells translational medicine\| PubMed ID: 33179450	2021
Nano-Biomaterials for the Delivery of Therapeutic and Monitoring Cues for Aortic Diseases. Frontiers in bioengineering and biotechnology\| PubMed ID: 33224934	2020
Learning curve of mitral valve repair: cumulative sum failure analysis from single high-volume center. Journal of thoracic disease\| PubMed ID: 33282358	2020
Cardiac Tissue Engineering on the Nanoscale. ACS biomaterials science & engineering\| PubMed ID: 33418765	2018
Coaxial Extrusion of Tubular Tissue Constructs Using a Gelatin/GelMA Blend Bioink. ACS biomaterials science & engineering\| PubMed ID: 33464071	2019
Engineering a Human Pluripotent Stem Cell-Based Microphysiological System for Studying the Metformin Response in Aortic Smooth Muscle Cells. Frontiers in bioengineering and biotechnology\| PubMed ID: 33816448	2021
Using deep learning to predict microvascular invasion in hepatocellular carcinoma based on dynamic contrast-enhanced MRI combined with clinical parameters. Journal of cancer research and clinical oncology\| PubMed ID: 33839938	2021
Feasibility of compressed sensing technique for isotropic dynamic contrast-enhanced liver magnetic resonance imaging. European journal of radiology\| PubMed ID: 33905976	2021
TM2D1 contributes the epithelial-mesenchymal transition of hepatocellular carcinoma via modulating AKT/β-catenin axis. American journal of cancer research\| PubMed ID: 33948373	2021
Current Pharmacological Management of Aortic Aneurysm. Journal of cardiovascular pharmacology\| PubMed ID: 33990514	2021
Clinical Performance of a Powered Surgical Stapler for Left Atrial Appendage Resection in a Video-Assisted Thoracoscopic Ablation for Patients with Nonvalvular Atrial Fibrillation. International heart journal\| PubMed ID: 34276010	2021
Inhibition of RhoA/MRTF-A signaling alleviates nucleus pulposus fibrosis induced by mechanical stress overload. Connective tissue research\| PubMed ID: 34420462	2022
Newly detected liver nodules with a history of colorectal cancer: are they metastatic? Review of 2,632 cases in a single center. Annals of translational medicine\| PubMed ID: 34422991	2021
Plasma proteomic profiling reveals biomarkers associated with aortic dilation in patients with bicuspid aortic valve. Annals of translational medicine\| PubMed ID: 34430623	2021
Minimally invasive co-injection of modular micro-muscular and micro-vascular tissues improves in situ skeletal muscle regeneration. Biomaterials\| PubMed ID: 34454373	2021
Enlargement of left ventricular outflow tract using an autologous pericardial patch for anterior mitral valve leaflet and septal myectomy through trans-mitral approach for the treatment of h... Journal of cardiac surgery\| PubMed ID: 34463383	2021
Aorta smooth muscle-on-a-chip reveals impaired mitochondrial dynamics as a therapeutic target for aortic aneurysm in bicuspid aortic valve disease. eLife\| PubMed ID: 34486519	2021
Interleukin-18 accelerates cardiac inflammation and dysfunction during ischemia/reperfusion injury by transcriptional activation of CXCL16. Cellular signalling\| PubMed ID: 34487815	2021
Global blue carbon accumulation in tidal wetlands increases with climate change. National science review\| PubMed ID: 34691731	2021
Minimally Invasive Bio-Chimney Technique for Postrepair Mitral Stenosis. The Annals of thoracic surgery\| PubMed ID: 34793764	2021
A predictive model integrating deep and radiomics features based on gadobenate dimeglumine-enhanced MRI for postoperative early recurrence of hepatocellular carcinoma. La Radiologia medica\| PubMed ID: 35129757	2022
A Multiparametric Fusion Deep Learning Model Based on DCE-MRI for Preoperative Prediction of Microvascular Invasion in Intrahepatic Cholangiocarcinoma. Journal of magnetic resonance imaging : JMRI\| PubMed ID: 35191550	2022
Cardiac tamponade caused by an ectopic intrapericardial thymic carcinoma. Cardiology journal\| PubMed ID: 35224716	2022
Gender differences in the dissection properties of ascending thoracic aortic aneurysms. Interactive cardiovascular and thoracic surgery\| PubMed ID: 35285896	2022
CD11b-Based Pre-Targeted SPECT/CT Imaging Allows for the Detection of Inflammation in Aortic Aneurysm. Journal of inflammation research\| PubMed ID: 35321320	2022
Electromechanical integrated recording of single cardiomyocyte in situ by multimodal microelectrode biosensing system. Biosensors & bioelectronics\| PubMed ID: 35635972	2022
Mechanical characterization and material modeling of ascending aortic aneurysm with different bicuspid aortic cusp fusion morphologies. Journal of the mechanical behavior of biomedical materials\| PubMed ID: 35636121	2022
Patient-derived microphysiological model identifies the therapeutic potential of metformin for thoracic aortic aneurysm. EBioMedicine\| PubMed ID: 35636318	2022
Associations of exposure to lead and cadmium with risk of all-cause and cardiovascular disease mortality among patients with type 2 diabetes. Environmental science and pollution research international\| PubMed ID: 35670945	2022