Takato Takenouchi

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells.

Cell culture on thin tissue sections commonly prepared for histopathology.

The chemical synthesis and binding affinity to the EGF receptor of the EGF-like domain of heparin-binding EGF-like growth factor (HB-EGF).

Alpha-synuclein up-regulates expression of caveolin-1 and down-regulates extracellular signal-regulated kinase activity in B103 neuroblastoma cells: role in the pathogenesis of Parkinson's disease.

Co-treatment with dexamethasone and octanoate induces adipogenesis in 3T3-L1 cells.

Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease.

Role of caveolin-1 and cytoskeletal proteins, actin and vimentin, in adipogenesis of bovine intramuscular preadipocyte cells.

Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line.

Establishment and characterization of SV40 large T antigen-immortalized cell lines derived from fetal bovine brain tissues after prolonged cryopreservation.

Microglial cell line established from prion protein-overexpressing mice is susceptible to various murine prion strains.

alpha-Synuclein stimulates differentiation of osteosarcoma cells: relevance to down-regulation of proteasome activity.

Lysophosphatidylcholine potentiates Ca2+ influx, pore formation and p44/42 MAP kinase phosphorylation mediated by P2X7 receptor activation in mouse microglial cells.

Prion infection correlates with hypersensitivity of P2X7 nucleotide receptor in a mouse microglial cell line.

Activin as an anti-inflammatory cytokine produced by microglia.

Lysophospholipids and ATP mutually suppress maturation and release of IL-1 beta in mouse microglial cells using a Rho-dependent pathway.

[Establishment and characterization of prion-infected microglial cells].

Lactoferrin induces cell surface retention of prion protein and inhibits prion accumulation.

Establishment of an SV40 large T antigen-immortalized bovine brain cell line and its neuronal differentiation by dibutyryl-cyclic AMP.

Differential microglial activation between acute stress and lipopolysaccharide treatment.

Microglial activation is inhibited by corticosterone in dopaminergic neurodegeneration.

The activation of P2X7 receptor impairs lysosomal functions and stimulates the release of autophagolysosomes in microglial cells.

The role of the P2X7 receptor signaling pathway for the release of autolysosomes in microglial cells.

Protective role of endogenous gangliosides for lysosomal pathology in a cellular model of synucleinopathies.

Modulation of the ATP-lnduced release and processing of IL-1beta in microglial cells.

Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models.

gamma-Irradiation induces P2X(7) receptor-dependent ATP release from B16 melanoma cells.

P2X7 receptor signaling pathway as a therapeutic target for neurodegenerative diseases.

A novel isolation method for macrophage-like cells from mixed primary cultures of adult rat liver cells.

A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain.

Cold stress induced morphological microglial activation and increased IL-1β expression in astroglial cells in rat brain.

Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-catenin.

Isolation and characterization of macrophages from a mixed primary culture of bovine liver cells.

The activation of P2X7 receptor induces cathepsin D-dependent production of a 20-kDa form of IL-1β under acidic extracellular pH in LPS-primed microglial cells.

Identification of Fyn as the binding partner for the WASP N-terminal domain in T cells.

Carnosic acid, a pro-electrophilic compound, inhibits LPS-induced activation of microglia.

Critical Roles of the WASP N-Terminal Domain and Btk in LPS-Induced Inflammatory Response in Macrophages.