Antonio Bertoletti

Emerging Infectious Diseases Program, DUKE-NUS Graduate Medical School

Affiliated withDUKE-NUS Graduate Medical School

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2019

Other Publications

Article	Year
Therapeutic vaccination and novel strategies to treat chronic HBV infection. Expert review of gastroenterology & hepatology\| PubMed ID: 19817676	2009
Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans. PLoS pathogens\| PubMed ID: 20808900	2010
Targeting hepatitis B virus-infected cells with a T-cell receptor-like antibody. Journal of virology\| PubMed ID: 21159876	2011
HBV-Specific Adaptive Immunity. Viruses\| PubMed ID: 21994540	2009
Preserved T-cell function in children and young adults with immune-tolerant chronic hepatitis B. Gastroenterology\| PubMed ID: 22710188	2012
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells. Immunity\| PubMed ID: 22795876	2012
Differential targeting of viral components by CD4+ versus CD8+ T lymphocytes in dengue virus infection. Journal of virology\| PubMed ID: 23255803	2013
Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases. European journal of immunology\| PubMed ID: 23280567	2013
IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease. PLoS pathogens\| PubMed ID: 23633957	2013
Mobilizing monocytes to cross-present circulating viral antigen in chronic infection. The Journal of clinical investigation\| PubMed ID: 23908113	2013
A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus. Molecular therapy. Nucleic acids\| PubMed ID: 23941866	2013
Reduction of HBV replication prolongs the early immunological response to IFNα therapy. Journal of hepatology\| PubMed ID: 23994382	2014
Immunoprevalence and immunodominance of HLA-Cw*0801-restricted T cell response targeting the hepatitis B virus envelope transmembrane region. Journal of virology\| PubMed ID: 24227846	2014
Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control? PLoS pathogens\| PubMed ID: 24367255	2013
Building and optimizing a virus-specific T cell receptor library for targeted immunotherapy in viral infections. Scientific reports\| PubMed ID: 24566718	2014
Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire. Nature communications\| PubMed ID: 24832684	2014
Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver. PLoS pathogens\| PubMed ID: 24967632	2014
Cancer immunotherapy: targeting the difference. Journal of hepatology\| PubMed ID: 24993529	2014
Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections. Hepatology (Baltimore, Md.)\| PubMed ID: 25048716	2015
The immune tolerant phase of chronic HBV infection: new perspectives on an old concept. Cellular & molecular immunology\| PubMed ID: 25176526	2015
Age-Dependent Immune Events during HBV Infection from Birth to Adulthood: An Alternative Interpretation. Frontiers in immunology\| PubMed ID: 25295036	2014
Hepatitis B: future curative strategies. Current opinion in infectious diseases\| PubMed ID: 25304392	2014
Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient. Journal of hepatology\| PubMed ID: 25308176	2015
Reply to: "To target or not to target viral antigens in HBV related HCC?". Journal of hepatology\| PubMed ID: 25711420	2015
Virus-specific T lymphocytes home to the skin during natural dengue infection. Science translational medicine\| PubMed ID: 25761891	2015
Trained immunity in newborn infants of HBV-infected mothers. Nature communications\| PubMed ID: 25807344	2015
Overview of the special issue on HBV immunity. Cellular & molecular immunology\| PubMed ID: 25864914	2015
Understanding the T cell immune response in SARS coronavirus infection. Emerging microbes & infections\| PubMed ID: 26038429	2012
Immune Response in Hepatitis B Virus Infection. Cold Spring Harbor perspectives in medicine\| PubMed ID: 26134480	2015
Advances in therapeutics for chronic hepatitis B. Hepatology international\| PubMed ID: 26363922	2016
T cell fitness in the liver: How can T cells keep it up? Journal of hepatology\| PubMed ID: 26943972	2016
Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection. Vaccine\| PubMed ID: 26954467	2016
Adaptive immunity in HBV infection. Journal of hepatology\| PubMed ID: 27084039	2016
Microfluidic models for adoptive cell-mediated cancer immunotherapies. Drug discovery today\| PubMed ID: 27185084	2016
Redirecting T Cell Specificity Using T Cell Receptor Messenger RNA Electroporation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 27236807	2016
Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 27357627	2016
HBV in 2016: Global and immunotherapeutic insights into hepatitis B. Nature reviews. Gastroenterology & hepatology\| PubMed ID: 28053337	2017
An accelerated rabies vaccine schedule based on toll-like receptor 3 (TLR3) agonist PIKA adjuvant augments rabies virus specific antibody and T cell response in healthy adult volunteers. Vaccine\| PubMed ID: 28118938	2017
Hepatitis C Virus-Specific T Cell Receptor mRNA-Engineered Human T Cells: Impact of Antigen Specificity on Functional Properties. Journal of virology\| PubMed ID: 28228595	2017
Immune Tolerant Chronic Hepatitis B: The Unrecognized Risks. Viruses\| PubMed ID: 28468285	2017
A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors. JCI insight\| PubMed ID: 28614795	2017
T-cell therapy for chronic viral hepatitis. Cytotherapy\| PubMed ID: 28847469	2017
Targeted Therapy of Hepatitis B Virus-Related Hepatocellular Carcinoma: Present and Future. Diseases (Basel, Switzerland)\| PubMed ID: 28933390	2016
CD137L dendritic cells induce potent response against cancer-associated viruses and polarize human CD8 T cells to Tc1 phenotype. Cancer immunology, immunotherapy : CII\| PubMed ID: 29508025	2018
Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3. Gastroenterology\| PubMed ID: 29550589	2018
Editorial overview: Antiviral strategies: Virological and immunological basis for HBV cure. Current opinion in virology\| PubMed ID: 29866361	2018
Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling. Nature communications\| PubMed ID: 30006605	2018
Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 30217730	2018
Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection. Journal of virology\| PubMed ID: 30518652	2019
Use of Expression Profiles of HBV DNA Integrated Into Genomes of Hepatocellular Carcinoma Cells to Select T Cells for Immunotherapy. Gastroenterology\| PubMed ID: 30711630	2019