Transgenic Oncogenesis and Genomics Section,
Laboratory of Cancer Biology and Genetics,
Transgenic Oncogenesis and Genomics Section, Laboratory of Cancer Biology and Genetics
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Development of PIN and prostate adenocarcinoma cell lines: a model system for multistage tumor progression.
Neoplasia (New York, N.Y.) Mar-Apr, 2002 | Pubmed ID: 11896566
Ventral prostate predominant l, a novel mouse gene expressed exclusively in the prostate.
The Prostate Apr, 2002 | Pubmed ID: 11920954
Initiating oncogenic event determines gene-expression patterns of human breast cancer models.
Proceedings of the National Academy of Sciences of the United States of America May, 2002 | Pubmed ID: 12011455
Adenovirus-mediated endostatin delivery results in inhibition of mammary gland tumor growth in C3(1)/SV40 T-antigen transgenic mice.
Cancer research Jul, 2002 | Pubmed ID: 12124322
Inhibition of the mammary carcinoma angiogenic switch in C3(1)/SV40 transgenic mice by a mutated form of human endostatin.
International journal of cancer. Journal international du cancer Sep, 2002 | Pubmed ID: 12209972
Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors.
Cancer research Sep, 2002 | Pubmed ID: 12235003
Validation of transgenic mammary cancer models: goals of the NCI Mouse Models of Human Cancer Consortium and the mammary cancer CD-ROM.
Transgenic research Dec, 2002 | Pubmed ID: 12509138
Development and characterization of a progressive series of mammary adenocarcinoma cell lines derived from the C3(1)/SV40 Large T-antigen transgenic mouse model.
Breast cancer research and treatment Jan, 2003 | Pubmed ID: 12602905
Comparative effects of lovastatin on mammary and prostate oncogenesis in transgenic mouse models.
Carcinogenesis Mar, 2003 | Pubmed ID: 12663504
Molecular differentiation of high- and moderate-grade human prostate cancer by cDNA microarray analysis.
Diagnostic molecular pathology : the American journal of surgical pathology, part B Jun, 2003 | Pubmed ID: 12766610
The use of genetically altered mice for breast cancer prevention studies.
The Journal of nutrition Jul, 2003 | Pubmed ID: 12840216
Induction of cre recombinase activity using modified androgen receptor ligand binding domains: a sensitive assay for ligand-receptor interactions.
Nucleic acids research Aug, 2003 | Pubmed ID: 12888538
Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.
Cancer research Aug, 2003 | Pubmed ID: 12907608
Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2004 | Pubmed ID: 14734487
Genomic approaches to understanding mammary tumor progression in transgenic mice and responses to therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2004 | Pubmed ID: 14734496
Interrogating mouse mammary cancer models: insights from gene expression profiling.
Journal of mammary gland biology and neoplasia Jul, 2003 | Pubmed ID: 14973376
Application of gene expression profiling for validating models of human breast cancer.
Toxicologic pathology Mar-Apr, 2004 | Pubmed ID: 15209407
Effects of pooling mRNA in microarray class comparisons.
Bioinformatics (Oxford, England) Dec, 2004 | Pubmed ID: 15247103
Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells.
The Journal of biological chemistry Oct, 2004 | Pubmed ID: 15294905
Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease.
Cancer research Sep, 2004 | Pubmed ID: 15342376
Gene expression profiling identifies a unique androgen-mediated inflammatory/immune signature and a PTEN (phosphatase and tensin homolog deleted on chromosome 10)-mediated apoptotic response specific to the rat ventral prostate.
Molecular endocrinology (Baltimore, Md.) Dec, 2004 | Pubmed ID: 15358834
Expression of the NF-kappaB-responsive gene BTG2 is aberrantly regulated in breast cancer.
Oncogene Oct, 2004 | Pubmed ID: 15378000
Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms.
Oncogene Jan, 2005 | Pubmed ID: 15592523
Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin.
International journal of cancer. Journal international du cancer May, 2005 | Pubmed ID: 15609296
Molecular mechanisms of breast cancer progression: lessons from mouse mammary cancer models and gene expression profiling.
Breast disease , 2004 | Pubmed ID: 15687699
The promise of genetically engineered mice for cancer prevention studies.
Nature reviews. Cancer Mar, 2005 | Pubmed ID: 15738982
Prostate cancer and the genomic revolution: Advances using microarray analyses.
Mutation research Aug, 2005 | Pubmed ID: 15950992
Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.
Endocrinology Dec, 2005 | Pubmed ID: 16141391
Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.
Genome biology , 2005 | Pubmed ID: 16207355
Distinct tumor stage-specific inhibitory effects of 2-methoxyestradiol in a breast cancer mouse model associated with Id-1 expression.
Cancer research Apr, 2006 | Pubmed ID: 16585173
Inhibition of estrogen-independent mammary carcinogenesis by disruption of growth hormone signaling.
Carcinogenesis Jan, 2007 | Pubmed ID: 16916863
2-methoxyestradiol induces mammary gland differentiation through amphiregulin-epithelial growth factor receptor-mediated signaling: molecular distinctions from the mammary gland of pregnant mice.
Endocrinology Mar, 2007 | Pubmed ID: 17158205
Increased expression of VEGF121/VEGF165-189 ratio results in a significant enhancement of human prostate tumor angiogenesis.
International journal of cancer. Journal international du cancer May, 2007 | Pubmed ID: 17278099
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.
Genome biology , 2007 | Pubmed ID: 17493263
Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.
Cancer research Sep, 2007 | Pubmed ID: 17804718
Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms.
Cancer research Sep, 2007 | Pubmed ID: 17804756
Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.
Cancer research Nov, 2007 | Pubmed ID: 17974970
Comparing genetically engineered mouse mammary cancer models with human breast cancer by expression profiling.
Breast disease , 2007 | Pubmed ID: 18057542
Identification of tumor-initiating cells in a p53-null mouse model of breast cancer.
Cancer research Jun, 2008 | Pubmed ID: 18559513
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.
Cancer research Aug, 2008 | Pubmed ID: 18676848
Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models.
Breast cancer research : BCR , 2008 | Pubmed ID: 18828875
Human adrenomedullin up-regulates interleukin-13 receptor alpha2 chain in prostate cancer in vitro and in vivo: a novel approach to sensitize prostate cancer to anticancer therapy.
Cancer research Nov, 2008 | Pubmed ID: 19010904
VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop.
Experimental cell research Feb, 2010 | Pubmed ID: 20006606
Molecular characterization of the Ggamma-globin-Tag transgenic mouse model of hormone refractory prostate cancer: comparison to human prostate cancer.
The Prostate May, 2010 | Pubmed ID: 20058236
Genomic analyses as a guide to target identification and preclinical testing of mouse models of breast cancer.
Toxicologic pathology Jan, 2010 | Pubmed ID: 20080934
Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth.
European journal of cancer (Oxford, England : 1990) May, 2010 | Pubmed ID: 20304630
Gastric cancer-specific protein profile identified using endoscopic biopsy samples via MALDI mass spectrometry.
Journal of proteome research Aug, 2010 | Pubmed ID: 20557134
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment.
Cancer research Jul, 2010 | Pubmed ID: 20570886
Modeling metastasis biology and therapy in real time in the mouse lung.
The Journal of clinical investigation Aug, 2010 | Pubmed ID: 20644255
Identifying functional miRNA-mRNA regulatory modules with correspondence latent dirichlet allocation.
Bioinformatics (Oxford, England) Dec, 2010 | Pubmed ID: 20956247
Multivariate analysis of a 3D mass spectral image for examining tissue heterogeneity.
Integrative biology : quantitative biosciences from nano to macro Apr, 2011 | Pubmed ID: 21212877
A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.
PloS one , 2011 | Pubmed ID: 21364753
BMI1 suffers a degrading experience.
Cell cycle (Georgetown, Tex.) Jun, 2011 | Pubmed ID: 21593587
Distinctions in gastric cancer gene expression signatures derived from laser capture microdissection versus histologic macrodissection.
BMC medical genomics , 2011 | Pubmed ID: 21635755
Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage.
Genome biology , 2011 | Pubmed ID: 21846369
MicroRNA regulation in cancer-associated fibroblasts.
Cancer immunology, immunotherapy : CII Feb, 2012 | Pubmed ID: 22083346
miRNA signature associated with outcome of gastric cancer patients following chemotherapy.
BMC medical genomics Nov, 2011 | Pubmed ID: 22112324
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