Jeffrey E. Green

Development of PIN and prostate adenocarcinoma cell lines: a model system for multistage tumor progression.

Ventral prostate predominant l, a novel mouse gene expressed exclusively in the prostate.

Initiating oncogenic event determines gene-expression patterns of human breast cancer models.

Adenovirus-mediated endostatin delivery results in inhibition of mammary gland tumor growth in C3(1)/SV40 T-antigen transgenic mice.

Inhibition of the mammary carcinoma angiogenic switch in C3(1)/SV40 transgenic mice by a mutated form of human endostatin.

Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors.

Validation of transgenic mammary cancer models: goals of the NCI Mouse Models of Human Cancer Consortium and the mammary cancer CD-ROM.

Development and characterization of a progressive series of mammary adenocarcinoma cell lines derived from the C3(1)/SV40 Large T-antigen transgenic mouse model.

Comparative effects of lovastatin on mammary and prostate oncogenesis in transgenic mouse models.

Molecular differentiation of high- and moderate-grade human prostate cancer by cDNA microarray analysis.

The use of genetically altered mice for breast cancer prevention studies.

Induction of cre recombinase activity using modified androgen receptor ligand binding domains: a sensitive assay for ligand-receptor interactions.

Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.

Proceedings of the Third International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement.

Genomic approaches to understanding mammary tumor progression in transgenic mice and responses to therapy.

Interrogating mouse mammary cancer models: insights from gene expression profiling.

Application of gene expression profiling for validating models of human breast cancer.

Effects of pooling mRNA in microarray class comparisons.

Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells.

Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease.

Gene expression profiling identifies a unique androgen-mediated inflammatory/immune signature and a PTEN (phosphatase and tensin homolog deleted on chromosome 10)-mediated apoptotic response specific to the rat ventral prostate.

Expression of the NF-kappaB-responsive gene BTG2 is aberrantly regulated in breast cancer.

Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms.

Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin.

Molecular mechanisms of breast cancer progression: lessons from mouse mammary cancer models and gene expression profiling.

The promise of genetically engineered mice for cancer prevention studies.

Prostate cancer and the genomic revolution: Advances using microarray analyses.

Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.

Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.

Distinct tumor stage-specific inhibitory effects of 2-methoxyestradiol in a breast cancer mouse model associated with Id-1 expression.

Inhibition of estrogen-independent mammary carcinogenesis by disruption of growth hormone signaling.

2-methoxyestradiol induces mammary gland differentiation through amphiregulin-epithelial growth factor receptor-mediated signaling: molecular distinctions from the mammary gland of pregnant mice.

Increased expression of VEGF121/VEGF165-189 ratio results in a significant enhancement of human prostate tumor angiogenesis.

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.

Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.

Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms.

Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

Comparing genetically engineered mouse mammary cancer models with human breast cancer by expression profiling.

Identification of tumor-initiating cells in a p53-null mouse model of breast cancer.

Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models.

Human adrenomedullin up-regulates interleukin-13 receptor alpha2 chain in prostate cancer in vitro and in vivo: a novel approach to sensitize prostate cancer to anticancer therapy.

VEGF elicits epithelial-mesenchymal transition (EMT) in prostate intraepithelial neoplasia (PIN)-like cells via an autocrine loop.

Molecular characterization of the Ggamma-globin-Tag transgenic mouse model of hormone refractory prostate cancer: comparison to human prostate cancer.

Genomic analyses as a guide to target identification and preclinical testing of mouse models of breast cancer.

Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth.

Gastric cancer-specific protein profile identified using endoscopic biopsy samples via MALDI mass spectrometry.

Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment.

Modeling metastasis biology and therapy in real time in the mouse lung.

Identifying functional miRNA-mRNA regulatory modules with correspondence latent dirichlet allocation.

Multivariate analysis of a 3D mass spectral image for examining tissue heterogeneity.

A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients.

BMI1 suffers a degrading experience.

Distinctions in gastric cancer gene expression signatures derived from laser capture microdissection versus histologic macrodissection.

Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage.

MicroRNA regulation in cancer-associated fibroblasts.

miRNA signature associated with outcome of gastric cancer patients following chemotherapy.