Department of Molecular Biophysics and Biochemistry,
Department of Molecular Biophysics & Biochemistry,
Department of Physics
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A brief scientific biography of Prof. Alan J. Hunt.
Cellular and molecular bioengineering Dec, 2013 | Pubmed ID: 24683426
Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs.
Biophysical journal Jun, 2014 | Pubmed ID: 24896122
Stu2, the budding yeast XMAP215/Dis1 homolog, promotes assembly of yeast microtubules by increasing growth rate and decreasing catastrophe frequency.
The Journal of biological chemistry Oct, 2014 | Pubmed ID: 25172511
Quantitative cell biology: the essential role of theory.
Molecular biology of the cell Nov, 2014 | Pubmed ID: 25368416
The microtubule-based cytoskeleton is a component of a mechanical signaling pathway in fly campaniform receptors.
Biophysical journal Dec, 2014 | Pubmed ID: 25517144
The motility of axonemal dynein is regulated by the tubulin code.
Biophysical journal Dec, 2014 | Pubmed ID: 25658008
Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe.
eLife Nov, 2015 | Pubmed ID: 26576948
Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment.
Trends in cell biology Dec, 2015 | Pubmed ID: 26616192
Splicing of Nascent RNA Coincides with Intron Exit from RNA Polymerase II.
Cell Apr, 2016 | Pubmed ID: 27020755
Independent Control of the Static and Dynamic Components of the Chlamydomonas Flagellar Beat.
Current biology : CB 04, 2016 | Pubmed ID: 27040779
Microtubules: 50 years on from the discovery of tubulin.
Nature reviews. Molecular cell biology 04, 2016 | Pubmed ID: 27103327
Automatic optimal filament segmentation with sub-pixel accuracy using generalized linear models and B-spline level-sets.
Medical image analysis 08, 2016 | Pubmed ID: 27104582
Broken detailed balance at mesoscopic scales in active biological systems.
Science (New York, N.Y.) Apr, 2016 | Pubmed ID: 27126047
Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella.
eLife 05, 2016 | Pubmed ID: 27166516
A force-generating machinery maintains the spindle at the cell center during mitosis.
Science (New York, N.Y.) May, 2016 | Pubmed ID: 27230381
The Mitotic Spindle in the One-Cell C. elegans Embryo Is Positioned with High Precision and Stability.
Biophysical journal Oct, 2016 | Pubmed ID: 27760363
Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1.
Proceedings of the National Academy of Sciences of the United States of America 11, 2016 | Pubmed ID: 27803321
Curvature regulation of the ciliary beat through axonemal twist.
Physical review. E Oct, 2016 | Pubmed ID: 27841522
Structural Biology: A Force-Sensitive Ion Channel Springs to Life.
Current biology : CB 09, 2017 | Pubmed ID: 28950085
Physical Limits on the Precision of Mitotic Spindle Positioning by Microtubule Pushing forces: Mechanics of mitotic spindle positioning.
BioEssays : news and reviews in molecular, cellular and developmental biology 11, 2017 | Pubmed ID: 28960439
Structural Biology: Piezo Senses Tension through Curvature.
Current biology : CB Apr, 2018 | Pubmed ID: 29689211
Label-free high-speed wide-field imaging of single microtubules using interference reflection microscopy.
Journal of microscopy Oct, 2018 | Pubmed ID: 30044498
Heat Oscillations Driven by the Embryonic Cell Cycle Reveal the Energetic Costs of Signaling.
Developmental cell Mar, 2019 | Pubmed ID: 30713074
Spastin is a dual-function enzyme that severs microtubules and promotes their regrowth to increase the number and mass of microtubules.
Proceedings of the National Academy of Sciences of the United States of America 03, 2019 | Pubmed ID: 30837315
The dynamic and structural properties of axonemal tubulins support the high length stability of cilia.
Nature communications 04, 2019 | Pubmed ID: 31015426
Force Generated by Two Kinesin Motors Depends on the Load Direction and Intermolecular Coupling.
Physical review letters May, 2019 | Pubmed ID: 31144901
Nicotinamide adenine dinucleotides and their precursor NMN have no direct effect on microtubule dynamics in purified brain tubulin.
PloS one , 2019 | Pubmed ID: 31393939
The Kinetics of Nucleotide Binding to Isolated Chlamydomonas Axonemes Using UV-TIRF Microscopy.
Biophysical journal 08, 2019 | Pubmed ID: 31400919
Predicted Effects of Severing Enzymes on the Length Distribution and Total Mass of Microtubules.
Biophysical journal 12, 2019 | Pubmed ID: 31708162
Three Beads Are Better Than One.
Biophysical journal 01, 2020 | Pubmed ID: 31951531
Contribution of increasing plasma membrane to the energetic cost of early zebrafish embryogenesis.
Molecular biology of the cell 03, 2020 | Pubmed ID: 32049586
Purification of Ciliary Tubulin from Chlamydomonas reinhardtii.
Current protocols in protein science 06, 2020 | Pubmed ID: 32568459
Cutting, Amplifying, and Aligning Microtubules with Severing Enzymes.
Trends in cell biology 01, 2021 | Pubmed ID: 33183955
Physical bioenergetics: Energy fluxes, budgets, and constraints in cells.
Proceedings of the National Academy of Sciences of the United States of America 06, 2021 | Pubmed ID: 34140336
Focal laser stimulation of fly nociceptors activates distinct axonal and dendritic Ca signals.
Biophysical journal 08, 2021 | Pubmed ID: 34175294
The narrowing of dendrite branches across nodes follows a well-defined scaling law.
Proceedings of the National Academy of Sciences of the United States of America 07, 2021 | Pubmed ID: 34215693
Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nature structural & molecular biology 10, 2021 | Pubmed ID: 34556869
Counting fluorescently labeled proteins in tissues in the spinning disk microscope using single-molecule calibrations.
Molecular biology of the cell Mar, 2022 | Pubmed ID: 35323029
In Vitro Reconstitution of Microtubule Dynamics and Severing Imaged by Label-Free Interference-Reflection Microscopy.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35476326
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