Dr Rui Monteiro is a BHF Intermediate Basic Science Research Fellow and Birmingham Fellow at the University of Birmingham, UK. He graduated in Biochemistry from the University of Lisbon, Portugal and earned his PhD in Developmental Biology with Prof Christine Mummery at the Hubrecht Institute in Utrecht, The Netherlands.
During his PhD he developed a keen interest in the TGF/BMP signalling pathway. There, he generated transgenic reporters in mice to map BMP activity during embryonic development in mice and also identified the two zebrafish BMP type II receptors required for left-right asymmetry. In 2006, he joined Profr Roger Patient’s lab at the Weatherall Institute, University of Oxford to learn about developmental haematopoiesis and transcriptional regulation of cell fate decisions.
Dr Monteiro received a BHF Intermediate Basic Science Fellowship in 2014 to establish his own research group in the Radcliffe Department of Medicine at the University of Oxford, investigating TGF signalling and its role in the formation on blood stem cells. In 2016 he became a University Research Lecturer at Oxford and in 2018 he was recruited as faculty at the Institute of Cancer and Genomic Sciences, University of Birmingham. His lab research programme is focussed on the study of transcription factors and DNA elements (enhancers) that function to establish the genetic programming of haemogenic endothelial cells and blood stem cells, both in development and in disease.