Department of Neurobiology
Lu Zhou MD is a Life Science Research Professional in the Neurobiology Department at Stanford University School of Medicine. She obtained her medical degree from Capital Medical University in China. She then received a master’s degree in Immunology from San Francisco State University, with her thesis research performed in Carol Clayberger and Alan Krensky’s lab at Stanford University.
During the years in Ben Barres lab (2006-present), Dr. Zhou has focused on studying the development and function of different glial cell types in the central nervous system. Her work is pivotal in the establishment of multiple glia culturing systems and she is also specialized in neural transcriptomics. Her previous work on pericytes and endothelial cells has contributed to our understanding of blood-brain barrier formation and function. Dr. Zhou is currently pursuing basic research in neuroimmunology. By taking advantage of single-cell RNA sequencing, she is trying to dissect the vital roles microglia play in brain development, aging and disease, with hopes of finding new therapeutics for devastating brain disorders.
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2009 | Pubmed ID: 19129494
The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells.
PloS one Oct, 2010 | Pubmed ID: 21060791
Development of a method for the purification and culture of rodent astrocytes.
Neuron Sep, 2011 | Pubmed ID: 21903074
Genomic analysis of reactive astrogliosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2012 | Pubmed ID: 22553043
Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2012 | Pubmed ID: 22787045
Biomechanical properties and associated collagen composition in vaginal tissue of women with pelvic organ prolapse.
The Journal of urology Sep, 2012 | Pubmed ID: 22819408
Reprogramming of fibroblasts from older women with pelvic floor disorders alters cellular behavior associated with donor age.
Stem cells translational medicine Feb, 2013 | Pubmed ID: 23341439
Purification and culture of central nervous system endothelial cells.
Cold Spring Harbor protocols Jan, 2014 | Pubmed ID: 24371313
Purification of endothelial cells from rodent brain by immunopanning.
Cold Spring Harbor protocols Jan, 2014 | Pubmed ID: 24371317
Purification of pericytes from rodent optic nerve by immunopanning.
Cold Spring Harbor protocols Jun, 2014 | Pubmed ID: 24890207
Purification and culture of central nervous system pericytes.
Cold Spring Harbor protocols Jun, 2014 | Pubmed ID: 24890216
Proliferative behavior of vaginal fibroblasts from women with pelvic organ prolapse.
European journal of obstetrics, gynecology, and reproductive biology Dec, 2014 | Pubmed ID: 25461341
Schwann cells use TAM receptor-mediated phagocytosis in addition to autophagy to clear myelin in a mouse model of nerve injury.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2017 | Pubmed ID: 28874532
Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris.
Nature 10, 2018 | Pubmed ID: 30283141
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing.
Neuron 01, 2019 | Pubmed ID: 30606613
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