Department of Physiology and Pharmacology
Andrei S. Chagin has not added Biography.
If you are Andrei S. Chagin and would like to personalize this page please email our Author Liaison for assistance.
Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3'-kinase signaling pathway.
Endocrinology Mar, 2005 | Pubmed ID: 15576458
Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocyte proliferation and decreased apoptosis.
The Journal of endocrinology Feb, 2006 | Pubmed ID: 16461546
Tamoxifen induces permanent growth arrest through selective induction of apoptosis in growth plate chondrocytes in cultured rat metatarsal bones.
Bone May, 2007 | Pubmed ID: 17293177
Estrogens and growth: review.
Pediatric endocrinology reviews : PER Jun, 2007 | Pubmed ID: 17643080
Oestrogen receptors and linear bone growth.
Acta paediatrica (Oslo, Norway : 1992) Sep, 2007 | Pubmed ID: 17718780
GPR30 estrogen receptor expression in the growth plate declines as puberty progresses.
The Journal of clinical endocrinology and metabolism Dec, 2007 | Pubmed ID: 17878253
Effects of alendronate and pamidronate on cultured rat metatarsal bones: failure to prevent dexamethasone-induced growth retardation.
Bone Apr, 2008 | Pubmed ID: 18276203
Tamoxifen impairs both longitudinal and cortical bone growth in young male rats.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Aug, 2008 | Pubmed ID: 18348701
The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone.
The Journal of endocrinology May, 2008 | Pubmed ID: 18434348
Genes of importance in the hormonal regulation of growth plate cartilage.
Hormone research Apr, 2009 | Pubmed ID: 19407496
Catch-up growth after dexamethasone withdrawal occurs in cultured postnatal rat metatarsal bones.
The Journal of endocrinology Jan, 2010 | Pubmed ID: 19815587
Genetic regulation of the growth plate.
Frontiers in endocrinology , 2011 | Pubmed ID: 22654844
Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits.
PloS one , 2013 | Pubmed ID: 23840780
G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.
Nature communications Apr, 2014 | Pubmed ID: 24781502
Role of G-proteins in the differentiation of epiphyseal chondrocytes.
Journal of molecular endocrinology Oct, 2014 | Pubmed ID: 24982242
Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Dec, 2015 | Pubmed ID: 26077727
Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Autophagy , 2015 | Pubmed ID: 26259639
Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis.
Annals of the rheumatic diseases Mar, 2016 | Pubmed ID: 26438374
Effectors of mTOR-autophagy pathway: targeting cancer, affecting the skeleton.
Current opinion in pharmacology 06, 2016 | Pubmed ID: 26921601
Analysis of neural crest-derived clones reveals novel aspects of facial development.
Science advances Aug, 2016 | Pubmed ID: 27493992
Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 03, 2017 | Pubmed ID: 27965322
Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.
eLife 04, 2017 | Pubmed ID: 28414273
Regenerative medicine: Cartilage stem cells identified, but can they heal?
Nature reviews. Rheumatology 09, 2017 | Pubmed ID: 28794509
Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage.
eLife 06, 2018 | Pubmed ID: 29897331
Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.
Bone reports Jun, 2018 | Pubmed ID: 29955624
Genetic ablation of adenosine receptor A3 results in articular cartilage degeneration.
Journal of molecular medicine (Berlin, Germany) 10, 2018 | Pubmed ID: 30088034
Repair of Damaged Articular Cartilage: Current Approaches and Future Directions.
International journal of molecular sciences Aug, 2018 | Pubmed ID: 30103493
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.
Nature 03, 2019 | Pubmed ID: 30814736
Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2019 | Pubmed ID: 31285319
Effects of the selective GPER-1 agonist G1 on bone growth.
Endocrine connections Aug, 2019 | Pubmed ID: 31434056
1Department of Physiology and Pharmacology, Karolinska Institutet,
2Institute for Regenerative Medicine, Sechenov First Moscow State Medical University (Sechenov University),
3Department of Women's and Children's Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved