Andrei S. Chagin

Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3'-kinase signaling pathway.

Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocyte proliferation and decreased apoptosis.

Tamoxifen induces permanent growth arrest through selective induction of apoptosis in growth plate chondrocytes in cultured rat metatarsal bones.

Estrogens and growth: review.

Oestrogen receptors and linear bone growth.

GPR30 estrogen receptor expression in the growth plate declines as puberty progresses.

Effects of alendronate and pamidronate on cultured rat metatarsal bones: failure to prevent dexamethasone-induced growth retardation.

Tamoxifen impairs both longitudinal and cortical bone growth in young male rats.

The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone.

Genes of importance in the hormonal regulation of growth plate cartilage.

Catch-up growth after dexamethasone withdrawal occurs in cultured postnatal rat metatarsal bones.

Genetic regulation of the growth plate.

Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits.

G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.

Role of G-proteins in the differentiation of epiphyseal chondrocytes.

Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation.

Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.

Targeted deletion of Atg5 in chondrocytes promotes age-related osteoarthritis.

Effectors of mTOR-autophagy pathway: targeting cancer, affecting the skeleton.

Analysis of neural crest-derived clones reveals novel aspects of facial development.

Superficial cells are self-renewing chondrocyte progenitors, which form the articular cartilage in juvenile mice.

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.

Regenerative medicine: Cartilage stem cells identified, but can they heal?

Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage.

Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.

Genetic ablation of adenosine receptor A3 results in articular cartilage degeneration.

Repair of Damaged Articular Cartilage: Current Approaches and Future Directions.

A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.

Schwann cell precursors contribute to skeletal formation during embryonic development in mice and zebrafish.

Effects of the selective GPER-1 agonist G1 on bone growth.