Luis A. Pardo

Role of voltage-gated potassium channels in cancer.

Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference.

Different relevance of inactivation and F468 residue in the mechanisms of hEag1 channel blockage by astemizole, imipramine and dofetilide.

Re-expression of a developmentally restricted potassium channel in autoimmune demyelination: Kv1.4 is implicated in oligodendroglial proliferation.

Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity.

Eag1: an emerging oncological target.

Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis.

The voltage dependence of hEag currents is not determined solely by membrane-spanning domains.

Eag1 as a cancer target.

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors.

The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia.

Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots.

K(+) channels as therapeutic targets in oncology.

A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia.

Functional K(v)10.1 channels localize to the inner nuclear membrane.

Rapid internalization of the oncogenic K+ channel K(V)10.1.

Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy.

Physical and functional interaction of KV10.1 with Rabaptin-5 impacts ion channel trafficking.

Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1.

TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells.

Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice.

Human glioma-initiating cells show a distinct immature phenotype resembling but not identical to NG2 glia.

PIST (GOPC) modulates the oncogenic voltage-gated potassium channel KV10.1.

KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons.

The roles of K(+) channels in cancer.

Potassium channels in cell cycle and cell proliferation.

KV 10.1 opposes activity-dependent increase in Ca²⁺ influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.

Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.

CD133 Expression Is Not Synonymous to Immunoreactivity for AC133 and Fluctuates throughout the Cell Cycle in Glioma Stem-Like Cells.

Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes.

Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival.

Kv10.1 K(+) channel: from physiology to cancer.

SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments.

Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.

Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium.

Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin.

Ion channels, transporters and cancer ("INCA2015"): an international meeting in honor of Prof. Dr. Walter Stühmer.

In vivo imaging of tumour xenografts with an antibody targeting the potassium channel K10.1.

A new mechanism of voltage-dependent gating exposed by K10.1 channels interrupted between voltage sensor and pore.

Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer.

APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel K10.1.

Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel KV10.1.

New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question.