David K. C. Cooper

Xenotransplantation Program/Department of Surgery, University of Alabama at Birmingham

Affiliated withUniversity of Alabama at Birmingham

Research Area

Medicine

Biography

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JoVE Journal Publications

Article Total : 1	Year
Publication title	2020

Other Publications

Article	Year
Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning. The Journal of reproduction and development\| PubMed ID: 27725344	2017
Klotho attenuated antibody-mediated porcine endothelial cell activation and injury. Xenotransplantation\| PubMed ID: 28130792	2017
Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future. Cell transplantation\| PubMed ID: 28155815	2017
Human IL-6, IL-17, IL-1β, and TNF-α differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial ce... Xenotransplantation\| PubMed ID: 28303603	2017
Thomas E. Starzl, MD, PhD, 1926-2017. Xenotransplantation\| PubMed ID: 28421680	2017
Early clinical xenotransplantation experiences-An interview with Thomas E. Starzl, MD, PhD. Xenotransplantation\| PubMed ID: 28421681	2017
Altered expression of eNOS, prostacyclin synthase, prostaglandin G/H synthase, and thromboxane synthase in porcine aortic endothelial cells after exposure to human serum-relevance to xenotra... Cell biology international\| PubMed ID: 28462511	2017
Regulation of Clinical Xenotransplantation-Time for a Reappraisal. Transplantation\| PubMed ID: 28737658	2017
Financial aspects of organ procurement from deceased donors in the USA-Relevance to xenotransplantation. Xenotransplantation\| PubMed ID: 28741700	2017
Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model. Scientific reports\| PubMed ID: 28855711	2017
Xenotransplantation: past, present, and future. Current opinion in organ transplantation\| PubMed ID: 28901971	2017
Low anti-pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient? Xenotransplantation\| PubMed ID: 29067714	2017
The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation. Journal of immunology research\| PubMed ID: 29159187	2017
Life's defining moment: Christiaan Barnard and the first human heart transplant. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation\| PubMed ID: 29173384	2017
Joint FDA‐IXA Symposium, September 20, 2017. Xenotransplantation\| PubMed ID: 29193342	2017
The Sda and Cad glycan antigens and their glycosyltransferase, β1,4GalNAcT-II, in xenotransplantation. Xenotransplantation\| PubMed ID: 29430727	2018
Bringing Home The Bacon: Update on The State of Kidney Xenotransplantation. Blood purification\| PubMed ID: 29478054	2018
Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates: Recent Progress. Transplantation\| PubMed ID: 29538262	2018
Skin xenotransplantation: Historical review and clinical potential. Burns : journal of the International Society for Burn Injuries\| PubMed ID: 29602717	2018
Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAH. Acta biomaterialia\| PubMed ID: 29631050	2018
Is sensitization to pig antigens detrimental to subsequent allotransplantation? Xenotransplantation\| PubMed ID: 29655276	2018
Expression and Regulation Profile of Mature MicroRNA in the Pig: Relevance to Xenotransplantation. BioMed research international\| PubMed ID: 29750148	2018
Corrigendum to "The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation". Journal of immunology research\| PubMed ID: 29767012	2018
20th Anniversary of IXA, 1998-2018. Xenotransplantation\| PubMed ID: 29913043	2018
Porcine IL-6, IL-1β, and TNF-α regulate the expression of pro-inflammatory-related genes and tissue factor in human umbilical vein endothelial cells. Xenotransplantation\| PubMed ID: 29932258	2018
Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenografts. Archivum immunologiae et therapiae experimentalis\| PubMed ID: 29992337	2018
Christiaan Barnard-The surgeon who dared: The story of the first human-to-human heart transplant. Global cardiology science & practice\| PubMed ID: 30083541	2018
B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy. Transplant immunology\| PubMed ID: 30092338	2018
An approach to induction of tolerance to pig cardiac xenografts in neonates. Xenotransplantation\| PubMed ID: 30125392	2018
Xenotransplantation research and the 'International Journal of Surgery'. International journal of surgery (London, England)\| PubMed ID: 30237083	2018
Perspectives on the Optimal Genetically Engineered Pig in 2018 for Initial Clinical Trials of Kidney or Heart Xenotransplantation. Transplantation\| PubMed ID: 30247446	2018
Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy. Data in brief\| PubMed ID: 30294651	2018
The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome? Pediatric cardiology\| PubMed ID: 30302505	2019
Will donor-derived neoplasia be problematic after clinical pig organ or cell xenotransplantation? Xenotransplantation\| PubMed ID: 30411396	2019
Chronic dialysis in patients with end-stage renal disease: Relevance to kidney xenotransplantation. Xenotransplantation\| PubMed ID: 30456901	2019
Experimental Pig Heart Xenotransplantation-Recent Progress and Remaining Problems. The Annals of thoracic surgery\| PubMed ID: 30471272	2019
Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: A new syndrome of clinical importance? Xenotransplantation\| PubMed ID: 30485551	2019
Serum amyloid a as an indicator of impending xenograft failure: Experimental studies. International journal of surgery (London, England)\| PubMed ID: 30521954	2018
Financial support for xenotransplantation research. Xenotransplantation\| PubMed ID: 30605230	2019
Life-supporting porcine cardiac xenotransplantation: The Munich study. Xenotransplantation\| PubMed ID: 30657207	2019
Genetically-engineered pigs as sources for clinical red blood cell transfusion: What pathobiological barriers need to be overcome? Blood reviews\| PubMed ID: 30711308	2019
A review of pig liver xenotransplantation: Current problems and recent progress. Xenotransplantation\| PubMed ID: 30767272	2019
Carbohydrate antigen expression and anti-pig antibodies in New World capuchin monkeys: Relevance to studies of xenotransplantation. Xenotransplantation\| PubMed ID: 30770572	2019
Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation. Xenotransplantation\| PubMed ID: 30770591	2019
In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic Degeneration. The Annals of thoracic surgery\| PubMed ID: 30836101	2019
Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ Xenotransplantation. Comparative medicine\| PubMed ID: 30909988	2019
The "Baby Fae" baboon heart transplant-Potential cause of rejection. Xenotransplantation\| PubMed ID: 30932224	2019
Justification of specific genetic modifications in pigs for clinical organ xenotransplantation. Xenotransplantation\| PubMed ID: 30989742	2019
The complex functioning of the complement system in xenotransplantation. Xenotransplantation\| PubMed ID: 31033064	2019
Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejection. Xenotransplantation\| PubMed ID: 31077480	2019
A potential role of TLR2 in xenograft rejection of porcine iliac endothelial cells: An in vitro study. Xenotransplantation\| PubMed ID: 31127671	2019
Evidence for the important role of inflammation in xenotransplantation. Journal of inflammation (London, England)\| PubMed ID: 31148951	2019
LIFE-SUPPORTING KIDNEY XENOTRANSPLANTATION FROM GENETICALLY-ENGINEERED PIGS IN BABOONS: A COMPARISON OF TWO IMMUNOSUPPRESSIVE REGIMENS. Transplantation\| PubMed ID: 31283686	2019
TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression. Cell communication and signaling : CCS\| PubMed ID: 31307477	2019
Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article. International journal of surgery (London, England)\| PubMed ID: 31369877	2019
Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells. Xenotransplantation\| PubMed ID: 31433094	2019
Indicators of impending pig kidney and heart xenograft failure: Relevance to clinical organ xenotransplantation - Review article. International journal of surgery (London, England)\| PubMed ID: 31445094	2019
Human CTLA4-Ig therapy can give false-positive anti-pig antibody results in primates after xenotransplantation. Transplant immunology\| PubMed ID: 31472231	2019
Anti-Pig Antibody in Infants: Can a Genetically Engineered Pig Heart Bridge to Allotransplantation? The Annals of thoracic surgery\| PubMed ID: 31580857	2019
Decellularization methods for developing porcine corneal xenografts and future perspectives. Xenotransplantation\| PubMed ID: 31659811	2019
Selective inhibition of cyclooxygenase-2 protects porcine aortic endothelial cells from human antibody-mediated complement-dependent cytotoxicity. Xenotransplantation\| PubMed ID: 31724835	2019
Is interleukin-6 receptor blockade (tocilizumab) beneficial or detrimental to pig-to-baboon organ xenotransplantation? American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 31733178	2019
Clinical Pig Kidney Xenotransplantation: How Close Are We? Journal of the American Society of Nephrology : JASN\| PubMed ID: 31792154	2020
Meta-analysis of public perception toward xenotransplantation. Xenotransplantation\| PubMed ID: 31957115	2020
Introduction: The Present Status of Xenotransplantation Research. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32002898	2020
Pig-to-Macaque Islet Xenotransplantation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32002916	2020