Xenotransplantation Program/Department of Surgery
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Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning.
The Journal of reproduction and development Feb, 2017 | Pubmed ID: 27725344
Klotho attenuated antibody-mediated porcine endothelial cell activation and injury.
Xenotransplantation 01, 2017 | Pubmed ID: 28130792
Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future.
Cell transplantation 06, 2017 | Pubmed ID: 28155815
Human IL-6, IL-17, IL-1β, and TNF-α differently regulate the expression of pro-inflammatory related genes, tissue factor, and swine leukocyte antigen class I in porcine aortic endothelial cells.
Xenotransplantation 03, 2017 | Pubmed ID: 28303603
Thomas E. Starzl, MD, PhD, 1926-2017.
Xenotransplantation 03, 2017 | Pubmed ID: 28421680
Early clinical xenotransplantation experiences-An interview with Thomas E. Starzl, MD, PhD.
Xenotransplantation 03, 2017 | Pubmed ID: 28421681
Altered expression of eNOS, prostacyclin synthase, prostaglandin G/H synthase, and thromboxane synthase in porcine aortic endothelial cells after exposure to human serum-relevance to xenotransplantation.
Cell biology international Jul, 2017 | Pubmed ID: 28462511
Regulation of Clinical Xenotransplantation-Time for a Reappraisal.
Transplantation 08, 2017 | Pubmed ID: 28737658
Financial aspects of organ procurement from deceased donors in the USA-Relevance to xenotransplantation.
Xenotransplantation 07, 2017 | Pubmed ID: 28741700
Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model.
Scientific reports 08, 2017 | Pubmed ID: 28855711
Xenotransplantation: past, present, and future.
Current opinion in organ transplantation Dec, 2017 | Pubmed ID: 28901971
Low anti-pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient?
Xenotransplantation 11, 2017 | Pubmed ID: 29067714
The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation.
Journal of immunology research , 2017 | Pubmed ID: 29159187
Life's defining moment: Christiaan Barnard and the first human heart transplant.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 12, 2017 | Pubmed ID: 29173384
Joint FDA‐IXA Symposium, September 20, 2017.
Xenotransplantation 11, 2017 | Pubmed ID: 29193342
The Sda and Cad glycan antigens and their glycosyltransferase, β1,4GalNAcT-II, in xenotransplantation.
Xenotransplantation 03, 2018 | Pubmed ID: 29430727
Bringing Home The Bacon: Update on The State of Kidney Xenotransplantation.
Blood purification , 2018 | Pubmed ID: 29478054
Overcoming Coagulation Dysregulation in Pig Solid Organ Transplantation in Nonhuman Primates: Recent Progress.
Transplantation 07, 2018 | Pubmed ID: 29538262
Skin xenotransplantation: Historical review and clinical potential.
Burns : journal of the International Society for Burn Injuries 11, 2018 | Pubmed ID: 29602717
Reducing immunoreactivity of porcine bioprosthetic heart valves by genetically-deleting three major glycan antigens, GGTA1/β4GalNT2/CMAH.
Acta biomaterialia 05, 2018 | Pubmed ID: 29631050
Is sensitization to pig antigens detrimental to subsequent allotransplantation?
Xenotransplantation 05, 2018 | Pubmed ID: 29655276
Expression and Regulation Profile of Mature MicroRNA in the Pig: Relevance to Xenotransplantation.
BioMed research international , 2018 | Pubmed ID: 29750148
Corrigendum to "The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation".
Journal of immunology research , 2018 | Pubmed ID: 29767012
20th Anniversary of IXA, 1998-2018.
Xenotransplantation 05, 2018 | Pubmed ID: 29913043
Porcine IL-6, IL-1β, and TNF-α regulate the expression of pro-inflammatory-related genes and tissue factor in human umbilical vein endothelial cells.
Xenotransplantation 09, 2018 | Pubmed ID: 29932258
Transplant Tolerance: Current Insights and Strategies for Long-Term Survival of Xenografts.
Archivum immunologiae et therapiae experimentalis Jul, 2018 | Pubmed ID: 29992337
Christiaan Barnard-The surgeon who dared: The story of the first human-to-human heart transplant.
Global cardiology science & practice Jun, 2018 | Pubmed ID: 30083541
B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.
Transplant immunology 12, 2018 | Pubmed ID: 30092338
An approach to induction of tolerance to pig cardiac xenografts in neonates.
Xenotransplantation 11, 2018 | Pubmed ID: 30125392
Xenotransplantation research and the 'International Journal of Surgery'.
International journal of surgery (London, England) 10, 2018 | Pubmed ID: 30237083
Perspectives on the Optimal Genetically Engineered Pig in 2018 for Initial Clinical Trials of Kidney or Heart Xenotransplantation.
Transplantation 12, 2018 | Pubmed ID: 30247446
Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.
Data in brief Oct, 2018 | Pubmed ID: 30294651
The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome?
Pediatric cardiology Feb, 2019 | Pubmed ID: 30302505
Will donor-derived neoplasia be problematic after clinical pig organ or cell xenotransplantation?
Xenotransplantation 03, 2019 | Pubmed ID: 30411396
Chronic dialysis in patients with end-stage renal disease: Relevance to kidney xenotransplantation.
Xenotransplantation 03, 2019 | Pubmed ID: 30456901
Experimental Pig Heart Xenotransplantation-Recent Progress and Remaining Problems.
The Annals of thoracic surgery Apr, 2019 | Pubmed ID: 30471272
Episodes of hypovolemia/dehydration in baboons with pig kidney transplants: A new syndrome of clinical importance?
Xenotransplantation 03, 2019 | Pubmed ID: 30485551
Serum amyloid a as an indicator of impending xenograft failure: Experimental studies.
International journal of surgery (London, England) Dec, 2018 | Pubmed ID: 30521954
Financial support for xenotransplantation research.
Xenotransplantation 05, 2019 | Pubmed ID: 30605230
Life-supporting porcine cardiac xenotransplantation: The Munich study.
Xenotransplantation 05, 2019 | Pubmed ID: 30657207
Genetically-engineered pigs as sources for clinical red blood cell transfusion: What pathobiological barriers need to be overcome?
Blood reviews 05, 2019 | Pubmed ID: 30711308
A review of pig liver xenotransplantation: Current problems and recent progress.
Xenotransplantation 05, 2019 | Pubmed ID: 30767272
Carbohydrate antigen expression and anti-pig antibodies in New World capuchin monkeys: Relevance to studies of xenotransplantation.
Xenotransplantation 05, 2019 | Pubmed ID: 30770572
Potential pathological role of pro-inflammatory cytokines (IL-6, TNF-α, and IL-17) in xenotransplantation.
Xenotransplantation 05, 2019 | Pubmed ID: 30770591
In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic Degeneration.
The Annals of thoracic surgery Aug, 2019 | Pubmed ID: 30836101
Incidence of Neoplasia in Pigs and Its Relevance to Clinical Organ Xenotransplantation.
Comparative medicine Apr, 2019 | Pubmed ID: 30909988
The "Baby Fae" baboon heart transplant-Potential cause of rejection.
Xenotransplantation Apr, 2019 | Pubmed ID: 30932224
Justification of specific genetic modifications in pigs for clinical organ xenotransplantation.
Xenotransplantation Apr, 2019 | Pubmed ID: 30989742
The complex functioning of the complement system in xenotransplantation.
Xenotransplantation Apr, 2019 | Pubmed ID: 31033064
Circulating pig-specific DNA as a novel biomarker for monitoring xenograft rejection.
Xenotransplantation May, 2019 | Pubmed ID: 31077480
A potential role of TLR2 in xenograft rejection of porcine iliac endothelial cells: An in vitro study.
Xenotransplantation May, 2019 | Pubmed ID: 31127671
Evidence for the important role of inflammation in xenotransplantation.
Journal of inflammation (London, England) , 2019 | Pubmed ID: 31148951
LIFE-SUPPORTING KIDNEY XENOTRANSPLANTATION FROM GENETICALLY-ENGINEERED PIGS IN BABOONS: A COMPARISON OF TWO IMMUNOSUPPRESSIVE REGIMENS.
Transplantation Jun, 2019 | Pubmed ID: 31283686
TNF-α promotes human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells through downregulating P38-mediated Occludin expression.
Cell communication and signaling : CCS Jul, 2019 | Pubmed ID: 31307477
Is the renal subcapsular space the preferred site for clinical porcine islet xenotransplantation? Review article.
International journal of surgery (London, England) Jul, 2019 | Pubmed ID: 31369877
Downregulation of Gabarapl1 significantly attenuates antibody binding to porcine aortic endothelial cells.
Xenotransplantation Nov, 2019 | Pubmed ID: 31433094
Indicators of impending pig kidney and heart xenograft failure: Relevance to clinical organ xenotransplantation - Review article.
International journal of surgery (London, England) Oct, 2019 | Pubmed ID: 31445094
Human CTLA4-Ig therapy can give false-positive anti-pig antibody results in primates after xenotransplantation.
Transplant immunology 12, 2019 | Pubmed ID: 31472231
Anti-Pig Antibody in Infants: Can a Genetically Engineered Pig Heart Bridge to Allotransplantation?
The Annals of thoracic surgery Sep, 2019 | Pubmed ID: 31580857
Decellularization methods for developing porcine corneal xenografts and future perspectives.
Xenotransplantation Nov, 2019 | Pubmed ID: 31659811
Selective inhibition of cyclooxygenase-2 protects porcine aortic endothelial cells from human antibody-mediated complement-dependent cytotoxicity.
Xenotransplantation Nov, 2019 | Pubmed ID: 31724835
Is interleukin-6 receptor blockade (tocilizumab) beneficial or detrimental to pig-to-baboon organ xenotransplantation?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Nov, 2019 | Pubmed ID: 31733178
Clinical Pig Kidney Xenotransplantation: How Close Are We?
Journal of the American Society of Nephrology : JASN Jan, 2020 | Pubmed ID: 31792154
Meta-analysis of public perception toward xenotransplantation.
Xenotransplantation Jan, 2020 | Pubmed ID: 31957115
Introduction: The Present Status of Xenotransplantation Research.
Methods in molecular biology (Clifton, N.J.) , 2020 | Pubmed ID: 32002898
Pig-to-Macaque Islet Xenotransplantation.
Methods in molecular biology (Clifton, N.J.) , 2020 | Pubmed ID: 32002916
Yuanzheng Peng*,1,
Zhicheng Zou*,1,
Jiao Chen1,
Hancheng Zhang1,
Ying Lu1,
Rito Bittino2,
Hongxing Fu3,
David K. C. Cooper4,
Shan Lin1,
Mengtao Cao1,
Yifan Dai5,
Zhiming Cai1,
Lisha Mou1
1Shenzhen Xenotransplantation Medical Engineering Research and Development Center, Institute of Translational Medicine, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Health Science Center,
2Institute for Cellular Therapeutics, Allegheny-Singer Research Institute,
3School of Pharmaceutical Sciences, Wenzhou Medical University,
4Xenotransplantation Program/Department of Surgery, University of Alabama at Birmingham,
5Jiangsu Key Laboratory of Xenotransplantation, Nanjing Medical University