Department of Cell Biology and Molecular Genetics
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The frameshift signal of HIV-1 involves a potential intramolecular triplex RNA structure.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2002 | Pubmed ID: 11959986
New targets for antivirals: the ribosomal A-site and the factors that interact with it.
Virology Aug, 2002 | Pubmed ID: 12202206
An "integrated model" of programmed ribosomal frameshifting.
Trends in biochemical sciences Sep, 2002 | Pubmed ID: 12217519
The 9-A solution: how mRNA pseudoknots promote efficient programmed -1 ribosomal frameshifting.
RNA (New York, N.Y.) Feb, 2003 | Pubmed ID: 12554858
Delayed rRNA processing results in significant ribosome biogenesis and functional defects.
Molecular and cellular biology Mar, 2003 | Pubmed ID: 12588980
Decreased peptidyltransferase activity correlates with increased programmed -1 ribosomal frameshifting and viral maintenance defects in the yeast Saccharomyces cerevisiae.
RNA (New York, N.Y.) Aug, 2003 | Pubmed ID: 12869709
An in vivo dual-luciferase assay system for studying translational recoding in the yeast Saccharomyces cerevisiae.
RNA (New York, N.Y.) Aug, 2003 | Pubmed ID: 12869712
A programmed -1 ribosomal frameshift signal can function as a cis-acting mRNA destabilizing element.
Nucleic acids research , 2004 | Pubmed ID: 14762205
Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough.
RNA (New York, N.Y.) Nov, 2004 | Pubmed ID: 15388879
Systematic analysis of bicistronic reporter assay data.
Nucleic acids research , 2004 | Pubmed ID: 15561995
Torsional restraint: a new twist on frameshifting pseudoknots.
Nucleic acids research , 2005 | Pubmed ID: 15800212
A three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signal.
PLoS biology Jun, 2005 | Pubmed ID: 15884978
Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae.
Molecular genetics and genomics : MGG Oct, 2005 | Pubmed ID: 16047201
Identification of functionally important amino acids of ribosomal protein L3 by saturation mutagenesis.
Molecular and cellular biology Dec, 2005 | Pubmed ID: 16314511
Comparative study of the effects of heptameric slippery site composition on -1 frameshifting among different eukaryotic systems.
RNA (New York, N.Y.) Apr, 2006 | Pubmed ID: 16497657
Specific effects of ribosome-tethered molecular chaperones on programmed -1 ribosomal frameshifting.
Eukaryotic cell Apr, 2006 | Pubmed ID: 16607023
Efficient expression of the 15-kDa form of infectious pancreatic necrosis virus VP5 by suppression of a UGA codon.
Virus research Dec, 2006 | Pubmed ID: 16891025
An arc of unpaired "hinge bases" facilitates information exchange among functional centers of the ribosome.
Molecular and cellular biology Dec, 2006 | Pubmed ID: 17000775
Identification of functional, endogenous programmed -1 ribosomal frameshift signals in the genome of Saccharomyces cerevisiae.
Nucleic acids research , 2007 | Pubmed ID: 17158156
Ribosomal protein L3: influence on ribosome structure and function.
RNA biology May, 2004 | Pubmed ID: 17194937
Optimization of ribosome structure and function by rRNA base modification.
PloS one , 2007 | Pubmed ID: 17245450
Ribosomal protein L3: gatekeeper to the A site.
Molecular cell Mar, 2007 | Pubmed ID: 17386264
Programmed Ribosomal Frameshifting Goes Beyond Viruses: Organisms from all three kingdoms use frameshifting to regulate gene expression, perhaps signaling a paradigm shift.
Microbe (Washington, D.C.) Nov, 2006 | Pubmed ID: 17541450
Differentiating between near- and non-cognate codons in Saccharomyces cerevisiae.
PloS one , 2007 | Pubmed ID: 17565370
Integration of residue-specific acid cleavage into proteomic workflows.
Journal of proteome research Nov, 2007 | Pubmed ID: 17902642
Human ribosomal protein L13a is dispensable for canonical ribosome function but indispensable for efficient rRNA methylation.
RNA (New York, N.Y.) Dec, 2007 | Pubmed ID: 17921318
5S rRNA: Structure and Function from Head to Toe.
International journal of biomedical science : IJBS Jun, 2005 | Pubmed ID: 18074004
Evaluation of microwave-accelerated residue-specific acid cleavage for proteomic applications.
Journal of proteome research Feb, 2008 | Pubmed ID: 18189344
rRNA mutants in the yeast peptidyltransferase center reveal allosteric information networks and mechanisms of drug resistance.
Nucleic acids research Mar, 2008 | Pubmed ID: 18203742
Structure/function analysis of yeast ribosomal protein L2.
Nucleic acids research Apr, 2008 | Pubmed ID: 18263608
A new kinetic model reveals the synergistic effect of E-, P- and A-sites on +1 ribosomal frameshifting.
Nucleic acids research May, 2008 | Pubmed ID: 18344525
The role of programmed-1 ribosomal frameshifting in coronavirus propagation.
Frontiers in bioscience : a journal and virtual library , 2008 | Pubmed ID: 18508552
PRFdb: a database of computationally predicted eukaryotic programmed -1 ribosomal frameshift signals.
BMC genomics , 2008 | Pubmed ID: 18637175
Yeast ribosomal protein L10 helps coordinate tRNA movement through the large subunit.
Nucleic acids research Nov, 2008 | Pubmed ID: 18824477
The 3' proximal translational enhancer of Turnip crinkle virus binds to 60S ribosomal subunits.
RNA (New York, N.Y.) Nov, 2008 | Pubmed ID: 18824512
Ribosomal protein L3 functions as a 'rocker switch' to aid in coordinating of large subunit-associated functions in eukaryotes and Archaea.
Nucleic acids research Nov, 2008 | Pubmed ID: 18832371
The eukaryotic ribosome: current status and challenges.
The Journal of biological chemistry May, 2009 | Pubmed ID: 19117941
Expanding the ribosomal universe.
Structure (London, England : 1993) Dec, 2009 | Pubmed ID: 20004156
Achieving a golden mean: mechanisms by which coronaviruses ensure synthesis of the correct stoichiometric ratios of viral proteins.
Journal of virology May, 2010 | Pubmed ID: 20164235
Enhanced purity, activity and structural integrity of yeast ribosomes purified using a general chromatographic method.
RNA biology May-Jun, 2010 | Pubmed ID: 20404492
A molecular clamp ensures allosteric coordination of peptidyltransfer and ligand binding to the ribosomal A-site.
Nucleic acids research Nov, 2010 | Pubmed ID: 20660012
A flexible loop in yeast ribosomal protein L11 coordinates P-site tRNA binding.
Nucleic acids research Dec, 2010 | Pubmed ID: 20705654
The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed -1 ribosomal frameshifting.
Nucleic acids research Jan, 2011 | Pubmed ID: 20823091
Endogenous ribosomal frameshift signals operate as mRNA destabilizing elements through at least two molecular pathways in yeast.
Nucleic acids research Apr, 2011 | Pubmed ID: 21109528
Ribosome binding to a 5' translational enhancer is altered in the presence of the 3' untranslated region in cap-independent translation of turnip crinkle virus.
Journal of virology May, 2011 | Pubmed ID: 21389125
Mutations of highly conserved bases in the peptidyltransferase center induce compensatory rearrangements in yeast ribosomes.
RNA (New York, N.Y.) May, 2011 | Pubmed ID: 21441349
The central core region of yeast ribosomal protein L11 is important for subunit joining and translational fidelity.
Molecular genetics and genomics : MGG Jun, 2011 | Pubmed ID: 21519857
A rapid, inexpensive yeast-based dual-fluorescence assay of programmed--1 ribosomal frameshifting for high-throughput screening.
Nucleic acids research Aug, 2011 | Pubmed ID: 21602263
An extensive network of information flow through the B1b/c intersubunit bridge of the yeast ribosome.
PloS one , 2011 | Pubmed ID: 21625514
Evolution of a helper virus-derived, ribosome binding translational enhancer in an untranslated satellite RNA of Turnip crinkle virus.
Virology Oct, 2011 | Pubmed ID: 21862095
rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.
Molecular cell Nov, 2011 | Pubmed ID: 22099312
Control of gene expression by translational recoding.
Advances in protein chemistry and structural biology , 2012 | Pubmed ID: 22243583
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