Gurdon Institute,
Department of Genetics
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Differential localization of HDAC4 orchestrates muscle differentiation.
Nucleic acids research Aug, 2001 | Pubmed ID: 11504882
Acetylation of beta-catenin by CREB-binding protein (CBP).
The Journal of biological chemistry Jul, 2002 | Pubmed ID: 11973335
How microRNAs control cell division, differentiation and death.
Current opinion in genetics & development Oct, 2005 | Pubmed ID: 16099643
MicroRNA functions in animal development and human disease.
Development (Cambridge, England) Nov, 2005 | Pubmed ID: 16224045
Caenorhabditis elegans and friends in Los Angeles.
Genome biology , 2005 | Pubmed ID: 16277759
Requirement of bic/microRNA-155 for normal immune function.
Science (New York, N.Y.) Apr, 2007 | Pubmed ID: 17463290
miRNAs in cancer: approaches, aetiology, diagnostics and therapy.
Human molecular genetics Apr, 2007 | Pubmed ID: 17613543
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.
Genes & development Aug, 2007 | Pubmed ID: 17626790
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype.
Genome biology , 2007 | Pubmed ID: 17922911
MicroRNA: implications for cancer.
Virchows Archiv : an international journal of pathology Jan, 2008 | Pubmed ID: 18040713
microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells.
Immunity Dec, 2007 | Pubmed ID: 18055230
MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.
PloS one Mar, 2008 | Pubmed ID: 18320056
A comparative metabolomic study of NHR-49 in Caenorhabditis elegans and PPAR-alpha in the mouse.
FEBS letters May, 2008 | Pubmed ID: 18435929
Functional genomic, computational and proteomic analysis of C. elegans microRNAs.
Briefings in functional genomics & proteomics May, 2008 | Pubmed ID: 18565984
Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline.
Molecular cell Jul, 2008 | Pubmed ID: 18571451
Two Piwi proteins, Xiwi and Xili, are expressed in the Xenopus female germline.
RNA (New York, N.Y.) Feb, 2009 | Pubmed ID: 19144913
Abundant and dynamically expressed miRNAs, piRNAs, and other small RNAs in the vertebrate Xenopus tropicalis.
Genome research Oct, 2009 | Pubmed ID: 19628731
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans.
Nature structural & molecular biology Oct, 2009 | Pubmed ID: 19713957
Characterisation of microRNA expression in post-natal mouse mammary gland development.
BMC genomics Nov, 2009 | Pubmed ID: 19930549
The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans.
Nucleic acids research Jun, 2010 | Pubmed ID: 20176573
The conserved miR-51 microRNA family is redundantly required for embryonic development and pharynx attachment in Caenorhabditis elegans.
Genetics Jul, 2010 | Pubmed ID: 20421599
The microRNAs of Caenorhabditis elegans.
Seminars in cell & developmental biology Sep, 2010 | Pubmed ID: 20637886
A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans.
Nature methods Oct, 2010 | Pubmed ID: 20835247
Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.
PLoS genetics Oct, 2010 | Pubmed ID: 20975942
Natural and experimental infection of Caenorhabditis nematodes by novel viruses related to nodaviruses.
PLoS biology Jan, 2011 | Pubmed ID: 21283608
Regulation of pre-miRNA processing.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 21627031
A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing.
Biochemistry Sep, 2011 | Pubmed ID: 21815640
miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones.
Nature neuroscience Dec, 2011 | Pubmed ID: 22138647
A metabolomic strategy defines the regulation of lipid content and global metabolism by Δ9 desaturases in Caenorhabditis elegans.
BMC genomics Jan, 2012 | Pubmed ID: 22264337
Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2.
PloS one , 2012 | Pubmed ID: 22448270
RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans.
Genome research Jul, 2012 | Pubmed ID: 22454234
Function, targets, and evolution of Caenorhabditis elegans piRNAs.
Science (New York, N.Y.) Aug, 2012 | Pubmed ID: 22700655
piRNAs can trigger a multigenerational epigenetic memory in the germline of C. elegans.
Cell Jul, 2012 | Pubmed ID: 22738725
Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans.
PLoS genetics , 2012 | Pubmed ID: 22829772
Post-developmental microRNA expression is required for normal physiology, and regulates aging in parallel to insulin/IGF-1 signaling in C. elegans.
RNA (New York, N.Y.) Dec, 2012 | Pubmed ID: 23097426
A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks.
Molecular bioSystems Jul, 2013 | Pubmed ID: 23475189
The shaping and functional consequences of the microRNA landscape in breast cancer.
Nature May, 2013 | Pubmed ID: 23644459
Competition between virus-derived and endogenous small RNAs regulates gene expression in Caenorhabditis elegans.
Genome research Aug, 2013 | Pubmed ID: 23811144
RNAi pathways in the recognition of foreign RNA: antiviral responses and host-parasite interactions in nematodes.
Biochemical Society transactions Aug, 2013 | Pubmed ID: 23863148
Molecular biology. Is there social RNA?
Science (New York, N.Y.) Aug, 2013 | Pubmed ID: 23908213
MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2013 | Pubmed ID: 23960236
A deletion polymorphism in the Caenorhabditis elegans RIG-I homolog disables viral RNA dicing and antiviral immunity.
eLife Oct, 2013 | Pubmed ID: 24137537
Antiviral RNA interference in animals: piecing together the evidence.
Nature structural & molecular biology Nov, 2013 | Pubmed ID: 24197164
Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans.
Nature neuroscience Dec, 2013 | Pubmed ID: 24212673
PRDE-1 is a nuclear factor essential for the biogenesis of Ruby motif-dependent piRNAs in C. elegans.
Genes & development Apr, 2014 | Pubmed ID: 24696457
Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants.
Cell reports May, 2014 | Pubmed ID: 24767993
Getting a grip on piRNA cluster transcription.
Cell Jun, 2014 | Pubmed ID: 24906143
Small RNAs break out: the molecular cell biology of mobile small RNAs.
Nature reviews. Molecular cell biology Aug, 2014 | Pubmed ID: 25053358
Considerations when investigating lncRNA function in vivo.
eLife Aug, 2014 | Pubmed ID: 25124674
piRNAs: from biogenesis to function.
Development (Cambridge, England) Sep, 2014 | Pubmed ID: 25183868
Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2014 | Pubmed ID: 25258416
Formation and abundance of 5-hydroxymethylcytosine in RNA.
Chembiochem : a European journal of chemical biology Mar, 2015 | Pubmed ID: 25676849
Tertiary siRNAs mediate paramutation in C. elegans.
PLoS genetics Mar, 2015 | Pubmed ID: 25811365
E. coli OxyS non-coding RNA does not trigger RNAi in C. elegans.
Scientific reports Apr, 2015 | Pubmed ID: 25873159
Antiviral RNA Interference against Orsay Virus Is neither Systemic nor Transgenerational in Caenorhabditis elegans.
Journal of virology Dec, 2015 | Pubmed ID: 26401037
Genomic islands of speciation separate cichlid ecomorphs in an East African crater lake.
Science (New York, N.Y.) Dec, 2015 | Pubmed ID: 26680190
Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications.
RNA biology 05, 2017 | Pubmed ID: 26786754
tRNA fragments: novel players in intergenerational inheritance.
Cell research Apr, 2016 | Pubmed ID: 26902286
Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways.
PLoS pathogens Apr, 2016 | Pubmed ID: 27089431
Identification of small molecule inhibitors of the Lin28-mediated blockage of pre-let-7g processing.
Organic & biomolecular chemistry Nov, 2016 | Pubmed ID: 27731469
Transgenerational inheritance: Models and mechanisms of non-DNA sequence-based inheritance.
Science (New York, N.Y.) 10, 2016 | Pubmed ID: 27846492
Oral transfer of chemical cues, growth proteins and hormones in social insects.
eLife 11, 2016 | Pubmed ID: 27894417
2'-O-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA.
Journal of the American Chemical Society 02, 2017 | Pubmed ID: 28107630
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.
eLife 03, 2017 | Pubmed ID: 28294943
The Profile and Dynamics of RNA Modifications in Animals.
Chembiochem : a European journal of chemical biology 06, 2017 | Pubmed ID: 28449301
The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.
Developmental cell 08, 2017 | Pubmed ID: 28787591
An Alternative STAT Signaling Pathway Acts in Viral Immunity in .
mBio 09, 2017 | Pubmed ID: 28874466
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements.
Nature ecology & evolution Jan, 2018 | Pubmed ID: 29203920
SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting.
Development (Cambridge, England) 07, 2018 | Pubmed ID: 29945865
Terminal uridylyltransferases target RNA viruses as part of the innate immune system.
Nature structural & molecular biology 09, 2018 | Pubmed ID: 30104661
COMRADES determines in vivo RNA structures and interactions.
Nature methods 10, 2018 | Pubmed ID: 30202058
Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma.
Molecular psychiatry Oct, 2018 | Pubmed ID: 30374190
Whole-genome sequences of Malawi cichlids reveal multiple radiations interconnected by gene flow.
Nature ecology & evolution 12, 2018 | Pubmed ID: 30455444
The USTC co-opts an ancient machinery to drive piRNA transcription in .
Genes & development 01, 2019 | Pubmed ID: 30567997
Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment.
PLoS genetics 02, 2019 | Pubmed ID: 30735500
Identification of functional long non-coding RNAs in C. elegans.
BMC biology 02, 2019 | Pubmed ID: 30777050
A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly.
Molecular cell 05, 2019 | Pubmed ID: 31051140
Mature sperm small-RNA profile in the sparrow: implications for transgenerational effects of age on fitness.
Environmental epigenetics Apr, 2019 | Pubmed ID: 31139435
Sequencing cell-type-specific transcriptomes with SLAM-ITseq.
Nature protocols 08, 2019 | Pubmed ID: 31243395
NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs.
Nucleic acids research 09, 2019 | Pubmed ID: 31276587
Publisher Correction: Sequencing cell-type-specific transcriptomes with SLAM-ITseq.
Nature protocols Aug, 2019 | Pubmed ID: 31296964
Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration.
Nature cell biology 11, 2019 | Pubmed ID: 31685987
Ancestral Hybridization Facilitated Species Diversification in the Lake Malawi Cichlid Fish Adaptive Radiation.
Molecular biology and evolution Apr, 2020 | Pubmed ID: 31821500
Cysteine synthases CYSL-1 and CYSL-2 mediate C. elegans heritable adaptation to P. vranovensis infection.
Nature communications Apr, 2020 | Pubmed ID: 32269224
A Family of Argonaute-Interacting Proteins Gates Nuclear RNAi.
Molecular cell Apr, 2020 | Pubmed ID: 32348780
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