Jordan K. Vance
Department of Microbiology,
Immunology,
& Cell Biology,
Department of Microbiology, Immunology, & Cell Biology
West Virginia University School of Medicine
Jordan Vance is a graduate student at West Virginia University in the Department of Microbiology, Immunology, and Cell Biology. She received her B.S. in immunology and medical microbiology in 2020 from WVU. She is currently pursuing a PhD in immunology and microbial pathogenesis. Under the mentorship of Dr. Cory Robinson, she has helped develop a neonatal mouse model of gram-negative bacterial sepsis. Using this model, she has characterized elements of the neonatal immune system. Specifically, her research has focused on myeloid-derived suppressor cells and the immune-suppressive cytokine interleukin-27. Her graduate work focuses on the mechanisms behind IL-27 and other elements that characterize differences between adult and neonatal immunity.
Murine myeloid-derived suppressor cells are a source of elevated levels of interleukin-27 in early life and compromise control of bacterial infection.
Immunology and cell biology 05, 2019 | Pubmed ID: 30575117
Elevated Levels of Interleukin-27 in Early Life Compromise Protective Immunity in a Mouse Model of Gram-Negative Neonatal Sepsis.
Infection and immunity 02, 2020 | Pubmed ID: 31818960
Neonatal low-density granulocytes internalize and kill bacteria but suppress monocyte function using extracellular DNA.
Journal of cell science Mar, 2021 | Pubmed ID: 33589502
Myeloid-Derived Suppressor Cells Gain Suppressive Function during Neonatal Bacterial Sepsis.
International journal of molecular sciences Jun, 2021 | Pubmed ID: 34208904
Interleukin-27-dependent transcriptome signatures during neonatal sepsis.
Frontiers in immunology , 2023 | Pubmed ID: 36891292
Neonatal Mouse Bone Marrow Isolation and Preparation of Bone Marrow-Derived Macrophages
