Anne-Kathrin Schott is a Project Leader at ACA CELL Biotech GmbH in Heidelberg, Germany. At ACA CELL Biotech GmbH her role encompasses mainly protein research and the application of BD-PSCs in regenerative medicine.
She received her Bachelor's Degree from Karlsruhe Institute of Technology (KIT) and her PhD at the Technical University of Munich (TUM), Germany.
During training, Dr Anne-Kathrin gained comprehensive and extensive experience in the field of Protein Chemistry as a Post-Doctoral fellow in different reference laboratories throughout Europe (Global Kinase Initiative at AstraZeneca in Manchester (United Kingdom), Structural Biology Laboratory at the Centro de Investigation Principe Felipe in Valencia (Spain), Roland Schüle`s Lab at the University of Freiburg Medical Centre in Freiburg (Germany)).
Selected publications:
Becker-Kojić, Z. A., Schott, A. K., Zipančić, I., Hernándaz-Rabaza, V. GM-Free Generation of Blood-Derived Neuronal Cells. J. Vis. Exp. (168), e6134, doi:10.3791/61634 (2021).
Becker-Kojić ZA, Schott A, Zipančić I, Herrenz-Perez V, Hernándaz-Rabaza V, Ureña-Peralta JJ, Rubio MP, Rosello MG, Stojkovic M and Garcia-Verdugo JM. World 1st Neuro Congress in Basel 4-7 September 2014: Neuronal differentiation of human ACA-generated pluripotent stem cells and their potential application in cell replacement therapy.
Sukhikh GT, Becker-Kojić Z, Kogan EA, Demura TA, Faizullina NM, Nizyaeva NV, Schott A, Ureña-Peralta JJ, Askol'skaya SI, Popov YV. Expression and intracellular localization of ACA and TRA-1-81 in smooth muscle cell tumors. Bull Exp Biol Med. 2013 Aug;155(4):530-5.
Wagner, T., Greschik, H., Burgahn, T., Schmidtkunz, K., Schott, A. K., McMillan, J., Baranauskienė, L., Xiong, Y., Fedorov, O., Jin, J., Oppermann, U., Matulis, D., Schüle, R., & Jung, M. (2016). Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform. Nucleic acids research, 44(9).
Metzger E, Willmann D, McMillan J, Forne I, Metzger P, Gerhardt S, Petroll K, von Maessenhausen A, Urban S, Schott AK, Espejo A, Eberlin A, Wohlwend D, Schüle KM, Schleicher M, Perner S, Bedford MT, Jung M, Dengjel J, Flaig R, Imhof A, Einsle O, Schüle R. Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation. Nat Struct Mol Biol. 2016 Feb;23(2):132-9.
Roldós V, Carbajo RJ, Schott AK, Pineda-Lucena A, Ochoa-Callejero L, Martínez A, Ramos A, de Pascual-Teresa B. Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments. Eur J Med Chem. 2012 Sep;55:262-72.
Norman RA, Schott AK, Andrews DM, Breed J, Foote KM, Garner AP, Ogg D, Orme JP, Pink JH, Roberts K, Rudge DA, Thomas AP, Leach AG. Protein-ligand crystal structures can guide the design of selective inhibitors of the FGFR tyrosine kinase. J Med Chem. 2012 Jun 14;55(11):5003-12.
