Krzysztof Pyrc

Recent antiviral strategies against human coronavirus-related respiratory illnesses.

Human coronavirus NL63 and 229E seroconversion in children.

Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures.

Infection with human coronavirus NL63 enhances streptococcal adherence to epithelial cells.

Development of loop-mediated isothermal amplification assay for detection of human coronavirus-NL63.

Porphyromonas gingivalis enzymes enhance infection with human metapneumovirus in vitro.

Use of sensitive, broad-spectrum molecular assays and human airway epithelium cultures for detection of respiratory pathogens.

Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63.

Bacterial proteases in disease - role in intracellular survival, evasion of coagulation/ fibrinolysis innate defenses, toxicoses and viral infections.

Inactivation of epidermal growth factor by Porphyromonas gingivalis as a potential mechanism for periodontal tissue damage.

Novel polymeric inhibitors of HCoV-NL63.

HexaPrime: a novel method for detection of coronaviruses.

Staphylococcus aureus proteases degrade lung surfactant protein A potentially impairing innate immunity of the lung.

Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD).

Stability of infectious human coronavirus NL63.

Citrullination alters immunomodulatory function of LL-37 essential for prevention of endotoxin-induced sepsis.

Human coronavirus NL63 utilizes heparan sulfate proteoglycans for attachment to target cells.

The nucleocapsid protein of human coronavirus NL63.

The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular traps.

Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme.

Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems.

Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis.

Novel Polyanions Inhibiting Replication of Influenza Viruses.

HTCC: Broad Range Inhibitor of Coronavirus Entry.

Type III CRISPR complexes from Thermus thermophilus.

Substrate profiling of Zika virus NS2B-NS3 protease.

Structural Characterization of Human Coronavirus NL63 N Protein.

Biopolymeric nano/microspheres for selective and reversible adsorption of coronaviruses.

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

Novel peptidyl α-aminoalkylphosphonates as inhibitors of hepatitis C virus NS3/4A protease.

Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) RNAs in the Porphyromonas gingivalis CRISPR-Cas I-C System.

Inhibition of Herpes Simplex Viruses by Cationic Dextran Derivatives.

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells.

Entry of Human Coronavirus NL63 into the Cell.

APOBEC3-mediated restriction of RNA virus replication.

Early events during human coronavirus OC43 entry to the cell.

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells.

Novel coronavirus-like particles targeting cells lining the respiratory tract.

One Step Beyond: Design of Substrates Spanning Primed Positions of Zika Virus NS2B-NS3 Protease.

Phosphonate inhibitors of West Nile virus NS2B/NS3 protease.

Synthetic sulfonated derivatives of poly(allylamine hydrochloride) as inhibitors of human metapneumovirus.

Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors.

Zika virus: mapping and reprogramming the entry.

Detection of legal highs in the urine of methadone-treated patient by LC-MS.

Highly Effective and Safe Polymeric Inhibitors of Herpes Simplex Virus in Vitro and in Vivo.

Membrane Protein of Human Coronavirus NL63 Is Responsible for Interaction with the Adhesion Receptor.

Cat flu: Broad spectrum polymeric antivirals.

MASS SPECTROMETRY IN VIROLOGICAL SCIENCES.

Berberine Hampers Influenza A Replication through Inhibition of MAPK/ERK Pathway.

Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection.

Replication of Severe Acute Respiratory Syndrome Coronavirus 2 in Human Respiratory Epithelium.

Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions.

Effects of host genetic variations on response to, susceptibility and severity of respiratory infections.

Effectiveness of Lung Transplantation in Patients With Interstitial Lung Diseases.

Visualizing Coronavirus Entry into Cells.

In Vitro Inhibition of Zika Virus Replication with Poly(Sodium 4-Styrenesulfonate).

Electrochemical Immunosensors Based on Screen-Printed Gold and Glassy Carbon Electrodes: Comparison of Performance for Respiratory Syncytial Virus Detection.

HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV.

Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1.

Battle at the entrance gate: CIITA as a weapon to prevent the internalization of SARS-CoV-2 and Ebola viruses.

The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans.