Gergely Rona

Department of Biochemistry and Molecular Pharmacology,
Laura and Isaac Perlmutter Cancer Center,
Howard Hughes Medical Institute

New York University School of Medicine

BIOGRAPHY

Currently I work as a Postdoctoral Fellow at the NYU Grossman School of Medicine and at HHMI in the field of DNA Damage and Repair. As a molecular biologist, I am trying to gain a better understanding about the fundamental processes that maintain genomic integrity within our cells. I find it intriguing how information encoded in our genome is maintained with an unparalleled precision yet at the same time is plastic enough to be able to adopt to environmental changes. DNA repair is also crucial in cancer biology as mis-regulation of this process is often a driving force of several cancer types and diseases.

PUBLICATIONS

Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2.

Molecular cell Nov, 2016 | Pubmed ID: 27773672

Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins.

Scientific reports 02, 2017 | Pubmed ID: 28211907

PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading.

eLife 07, 2018 | Pubmed ID: 29985131

CRISPR/Cas9-Mediated Knock-Out of dUTPase in Mice Leads to Early Embryonic Lethality.

Biomolecules 04, 2019 | Pubmed ID: 30987342

Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells.

Cells 10, 2019 | Pubmed ID: 31671862

Mixed ubiquitin chains regulate DNA repair.

Genes & development 12, 2019 | Pubmed ID: 31792015

Interaction between NSMCE4A and GPS1 links the SMC5/6 complex to the COP9 signalosome.

BMC molecular and cell biology May, 2020 | Pubmed ID: 32384871

Genome-wide alterations of uracil distribution patterns in human DNA upon chemotherapeutic treatments.

eLife 09, 2020 | Pubmed ID: 32956035

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.

Nature Apr, 2021 | Pubmed ID: 33854232

CRL4 is a master regulator of D-type cyclins.

Nature Apr, 2021 | Pubmed ID: 33854235

The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.

Cell death and differentiation Feb, 2022 | Pubmed ID: 34862481

Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes.

Cancer discovery Apr, 2023 | Pubmed ID: 36715552

INSTITUTIONS

New York University School of Medicine

NYU Grossman School of Medicine

NYU Langone Health

HUN-REN Research Centre for Natural Sciences

JOVE ARTICLES

Laser Micro-Irradiation to Study DNA Recruitment During S Phase

Bearach Miwatani-Minter^1,2,

Gergely Rona^1,2,3

¹Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine,

²Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine,

³Howard Hughes Medical Institute, New York University School of Medicine

Biology

Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle

Qingyue Zhang^1,2,

Marc A. Kerzhnerman^1,2,

Nelson García-Vázquez^1,2,3,

Gergely Rona^1,2,4,5

¹Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine,

²The Laura and Isaac Perlmutter Cancer Center, NYU Langone Health,

³Department of Cell Biology, NYU Grossman School of Medicine,

⁴Howard Hughes Medical Institute, NYU Grossman School of Medicine,

⁵Institute of Enzymology, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences

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Gergely Rona

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Biochemistry and Molecular Pharmacology,Laura and Isaac Perlmutter Cancer Center,Howard Hughes Medical Institute

New York University School of Medicine

Laser Micro-Irradiation to Study DNA Recruitment During S Phase

Visualizing Single-Stranded DNA Foci in the G1 Phase of the Cell Cycle

Department of Biochemistry and Molecular Pharmacology,
Laura and Isaac Perlmutter Cancer Center,
Howard Hughes Medical Institute